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P32943 (CGS6_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 114. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
S-phase entry cyclin-6
Gene names
Name:CLB6
Ordered Locus Names:YGR109C
ORF Names:G5970
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length380 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Involved in G1/S and or S phase progression. Interacts with CDC28.

Developmental stage

Maximally expressed just before cell cycle start.

Sequence similarities

Belongs to the cyclin family. Cyclin AB subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 380380S-phase entry cyclin-6
PRO_0000080409

Experimental info

Sequence conflict771T → S in CAA51408. Ref.2
Sequence conflict921P → S in CAA51408. Ref.2
Sequence conflict1091I → M in CAA51408. Ref.2
Sequence conflict2231F → L in CAA49894. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P32943 [UniParc].

Last modified October 1, 1996. Version 2.
Checksum: C8A4284091C64F87

FASTA38044,145
        10         20         30         40         50         60 
MNCIPSPISE RKIQINNEDC IGKENAFHTI PRESSINLTP HSTNEKKVLS EVNSNKIDSL 

        70         80         90        100        110        120 
QLPRGKLQRD STHLEKTRKR QLSNDSTDPI EPKTVKKIKC HQWKNLDSIE MDDPFMVAEY 

       130        140        150        160        170        180 
TDSIFSHLYE KEIQMLPTHN YLMDTQSPYH LKSSMRALLI DWLVEVHEKF HCLPETLFLA 

       190        200        210        220        230        240 
INLLDRFLSQ NVVKLNKLQL LCITCLFIAC KFEEVKLPKI TNFAYVTDGA ATVEGIRKAE 

       250        260        270        280        290        300 
LFVLSSLGYN ISLPNPLNFI RRISKADNYC IETRNMAKFI MEYSICCNKF IHLKPSYLAA 

       310        320        330        340        350        360 
MSMYIARKIK NENSKWDETF IHYSGGIDIE SDPAFKDFIS ELVEDIAVPD TNLDSLRLKY 

       370        380 
KKPKHGMVYF KVFDWCKQKR 

« Hide

References

« Hide 'large scale' references
[1]"CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae."
Schwob E., Nasmyth K.
Genes Dev. 7:1160-1175(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: K1107.
[2]"A new pair of B-type cyclins from Saccharomyces cerevisiae that function early in the cell cycle."
Kuehne C., Linder P.
EMBO J. 12:3437-3447(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]Kuehne C.
Submitted (JAN-1994) to the EMBL/GenBank/DDBJ databases
Cited for: SEQUENCE REVISION TO C-TERMINUS.
[4]"The sequence of a 23.4 kb segment on the right arm of chromosome VII from Saccharomyces cerevisiae reveals CLB6, SPT6, RP28A and NUP57 genes, a Ty3 element and 11 new open reading frames."
Hansen M., Albers M., Backes U., Coblenz A., Leuther H., Neu R., Schreer A., Schaefer B., Zimmermann M., Wolf K.
Yeast 12:1273-1277(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[5]"The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E. expand/collapse author list , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[6]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[7]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X70436 Genomic DNA. Translation: CAA49894.1.
X72890 Genomic DNA. Translation: CAA51408.1.
Z72894 Genomic DNA. Translation: CAA97113.1.
AY693095 Genomic DNA. Translation: AAT93114.1.
BK006941 Genomic DNA. Translation: DAA08201.1.
PIRS64417.
RefSeqNP_011623.3. NM_001181238.3.

3D structure databases

ProteinModelPortalP32943.
SMRP32943. Positions 114-367.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid33353. 46 interactions.
IntActP32943. 8 interactions.
MINTMINT-4808884.
STRING4932.YGR109C.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYGR109C; YGR109C; YGR109C.
GeneID853003.
KEGGsce:YGR109C.

Organism-specific databases

CYGDYGR109c.
SGDS000003341. CLB6.

Phylogenomic databases

eggNOGCOG5024.
GeneTreeENSGT00750000117276.
HOGENOMHOG000000929.
KOK06651.
OMAHTIPRES.
OrthoDBEOG7FNCJX.

Enzyme and pathway databases

BioCycYEAST:G3O-30818-MONOMER.

Gene expression databases

GenevestigatorP32943.

Family and domain databases

Gene3D1.10.472.10. 2 hits.
InterProIPR013763. Cyclin-like.
IPR014400. Cyclin_A/B/D/E/F.
IPR004367. Cyclin_C-dom.
IPR006671. Cyclin_N.
[Graphical view]
PfamPF02984. Cyclin_C. 1 hit.
PF00134. Cyclin_N. 1 hit.
[Graphical view]
PIRSFPIRSF001771. Cyclin_A_B_D_E. 1 hit.
SMARTSM00385. CYCLIN. 2 hits.
[Graphical view]
SUPFAMSSF47954. SSF47954. 2 hits.
PROSITEPS00292. CYCLINS. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio972849.

Entry information

Entry nameCGS6_YEAST
AccessionPrimary (citable) accession number: P32943
Secondary accession number(s): D6VUP0
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1996
Last modified: July 9, 2014
This is version 114 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome VII

Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families