P32922 (SIGM2_REOVJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Inner capsid protein sigma-2
Short name=Sigma2

Gene names

Name:

S2

Organism

Reovirus type 2 (strain D5/Jones) (T2J) (Mammalian orthoreovirus 2) [Complete proteome]

Taxonomic identifier

10885 [NCBI]

Taxonomic lineage

Viruses › dsRNA viruses › Reoviridae › Spinareovirinae › Orthoreovirus › Mammalian orthoreovirus › Mammalian orthoreovirus 2

Virus host

Mammalia [TaxID: 40674]

Protein attributes

Sequence length	418 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Inner capsid (core) component.
Subunit structure	Interacts with protein mu-NS; in viral inclusions By similarity.
Subcellular location	Virion Potential. Note: Found in the inner capsid (150 copies).
Sequence similarities	Belongs to the orthoreovirus sigma-1 protein family.

Ontologies

Keywords
Cellular component	Virion
Molecular function	Capsid protein
Technical term	Complete proteome
Gene Ontology (GO)
Cellular_component	viral capsid Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 418	418	Inner capsid protein sigma-2		PRO_0000222750

Sequences

	Sequence		Length	Mass (Da)
	P32922 [UniParc]. Last modified October 1, 1993. Version 1. Checksum: E3D4351F55524213	FASTA	418	47,045
	10 20 30 40 50 60 MARAAFLFKT VGFGGLQNVP INDELASHLL RAGNSPWQLT QFLDWISLGR GLATSALVPT 70 80 90 100 110 120 AGSRYYQMSC LLSGTLQIPF RPNHRWGDVR FLRLVWSAPT LDGLVIAPPP ILAQPAIQAQ 130 140 150 160 170 180 ADRAYDCDDY PFLARDPRFK HRVYQQLSAI TLLNLTGFGP ISYVRVDEDM WSGDVSQLLM 190 200 210 220 230 240 NYFGHTFAEI AYTLCQASAN RPWEHDGTYA RMTQIVLSLF WLSYVGVIHQ HNTYRTFYFQ 250 260 270 280 290 300 CNRRGDAAEV WILSCSLTHS AQIRAGNRSL FVMPTSPDWN MDVNLILSST LTGCLCSGSQ 310 320 330 340 350 360 LPLIDNNSVP NVSRNIHGWT GRGGNQLHGF QVRRMITEYC DRLRRDGVMT PAQQMQIEAL 370 380 390 400 410 GDQTQQFKRD KLEAWALEDD QYNRAHPNST MFRTKPFTNA QWGRGNTAAT SAAIAALI

References

[1]

"The S2 gene nucleotide sequences of prototype strains of the three reovirus serotypes: characterization of reovirus core protein sigma 2." Dermody T.S., Schiff L.A., Nibert M.L., Coombs K.M., Fields B.N. J. Virol. 65:5721-5731(1991) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	L19775 Genomic RNA. Translation: AAA47248.1.
PIR	FOXRJS. B41306.
3D structure databases
ProteinModelPortal	P32922.
SMR	P32922. Positions 2-418.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR004317. Sigma_1_2_reovir. [Graphical view]
Pfam	PF03084. Sigma_1_2. 1 hit. [Graphical view]
ProDom	PD004419. Sigma_1_2_reovir. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

SIGM2_REOVJ

Accession

Primary (citable) accession number: P32922

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1993
Last sequence update:	October 1, 1993
Last modified:	April 3, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program