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P32922

- SIGM2_REOVJ

UniProt

P32922 - SIGM2_REOVJ

Protein

Inner capsid protein sigma-2

Gene

S2

Organism
Reovirus type 2 (strain D5/Jones) (T2J) (Mammalian orthoreovirus 2)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 45 (01 Oct 2014)
      Sequence version 1 (01 Oct 1993)
      Previous versions | rss
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    Functioni

    Inner capsid (core) component.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Inner capsid protein sigma-2
    Short name:
    Sigma2
    Gene namesi
    Name:S2
    OrganismiReovirus type 2 (strain D5/Jones) (T2J) (Mammalian orthoreovirus 2)
    Taxonomic identifieri10885 [NCBI]
    Taxonomic lineageiVirusesdsRNA virusesReoviridaeSpinareovirinaeOrthoreovirus
    Virus hostiMammalia [TaxID: 40674]
    ProteomesiUP000006370: Genome

    Subcellular locationi

    Virion Curated
    Note: Found in the inner capsid (150 copies).

    GO - Cellular componenti

    1. viral inner capsid Source: UniProtKB-KW

    Keywords - Cellular componenti

    Capsid protein, Inner capsid protein, Virion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 418418Inner capsid protein sigma-2PRO_0000222750Add
    BLAST

    Interactioni

    Subunit structurei

    Interacts with protein mu-NS; in viral inclusions.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliP32922.
    SMRiP32922. Positions 2-418.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    InterProiIPR004317. Sigma_1_2_reovir.
    [Graphical view]
    PfamiPF03084. Sigma_1_2. 1 hit.
    [Graphical view]
    ProDomiPD004419. Sigma_1_2_reovir. 1 hit.
    [Graphical view] [Entries sharing at least one domain]

    Sequencei

    Sequence statusi: Complete.

    P32922-1 [UniParc]FASTAAdd to Basket

    « Hide

    MARAAFLFKT VGFGGLQNVP INDELASHLL RAGNSPWQLT QFLDWISLGR    50
    GLATSALVPT AGSRYYQMSC LLSGTLQIPF RPNHRWGDVR FLRLVWSAPT 100
    LDGLVIAPPP ILAQPAIQAQ ADRAYDCDDY PFLARDPRFK HRVYQQLSAI 150
    TLLNLTGFGP ISYVRVDEDM WSGDVSQLLM NYFGHTFAEI AYTLCQASAN 200
    RPWEHDGTYA RMTQIVLSLF WLSYVGVIHQ HNTYRTFYFQ CNRRGDAAEV 250
    WILSCSLTHS AQIRAGNRSL FVMPTSPDWN MDVNLILSST LTGCLCSGSQ 300
    LPLIDNNSVP NVSRNIHGWT GRGGNQLHGF QVRRMITEYC DRLRRDGVMT 350
    PAQQMQIEAL GDQTQQFKRD KLEAWALEDD QYNRAHPNST MFRTKPFTNA 400
    QWGRGNTAAT SAAIAALI 418
    Length:418
    Mass (Da):47,045
    Last modified:October 1, 1993 - v1
    Checksum:iE3D4351F55524213
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L19775 Genomic RNA. Translation: AAA47248.1.
    PIRiB41306. FOXRJS.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L19775 Genomic RNA. Translation: AAA47248.1 .
    PIRi B41306. FOXRJS.

    3D structure databases

    ProteinModelPortali P32922.
    SMRi P32922. Positions 2-418.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR004317. Sigma_1_2_reovir.
    [Graphical view ]
    Pfami PF03084. Sigma_1_2. 1 hit.
    [Graphical view ]
    ProDomi PD004419. Sigma_1_2_reovir. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    ProtoNeti Search...

    Publicationsi

    1. "The S2 gene nucleotide sequences of prototype strains of the three reovirus serotypes: characterization of reovirus core protein sigma 2."
      Dermody T.S., Schiff L.A., Nibert M.L., Coombs K.M., Fields B.N.
      J. Virol. 65:5721-5731(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

    Entry informationi

    Entry nameiSIGM2_REOVJ
    AccessioniPrimary (citable) accession number: P32922
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1993
    Last sequence update: October 1, 1993
    Last modified: October 1, 2014
    This is version 45 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3