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P32922 (SIGM2_REOVJ) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Inner capsid protein sigma-2

Short name=Sigma2
Gene names
Name:S2
OrganismReovirus type 2 (strain D5/Jones) (T2J) (Mammalian orthoreovirus 2) [Complete proteome]
Taxonomic identifier10885 [NCBI]
Taxonomic lineageVirusesdsRNA virusesReoviridaeSpinareovirinaeOrthoreovirus
Virus hostMammalia [TaxID: 40674]

Protein attributes

Sequence length418 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Inner capsid (core) component.

Subunit structure

Interacts with protein mu-NS; in viral inclusions By similarity.

Subcellular location

Virion Potential. Note: Found in the inner capsid (150 copies).

Sequence similarities

Belongs to the orthoreovirus sigma-1 protein family.

Ontologies

Keywords
   Cellular componentCapsid protein
Inner capsid protein
Virion
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentviral inner capsid

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 418418Inner capsid protein sigma-2
PRO_0000222750

Sequences

Sequence LengthMass (Da)Tools
P32922 [UniParc].

Last modified October 1, 1993. Version 1.
Checksum: E3D4351F55524213

FASTA41847,045
        10         20         30         40         50         60 
MARAAFLFKT VGFGGLQNVP INDELASHLL RAGNSPWQLT QFLDWISLGR GLATSALVPT 

        70         80         90        100        110        120 
AGSRYYQMSC LLSGTLQIPF RPNHRWGDVR FLRLVWSAPT LDGLVIAPPP ILAQPAIQAQ 

       130        140        150        160        170        180 
ADRAYDCDDY PFLARDPRFK HRVYQQLSAI TLLNLTGFGP ISYVRVDEDM WSGDVSQLLM 

       190        200        210        220        230        240 
NYFGHTFAEI AYTLCQASAN RPWEHDGTYA RMTQIVLSLF WLSYVGVIHQ HNTYRTFYFQ 

       250        260        270        280        290        300 
CNRRGDAAEV WILSCSLTHS AQIRAGNRSL FVMPTSPDWN MDVNLILSST LTGCLCSGSQ 

       310        320        330        340        350        360 
LPLIDNNSVP NVSRNIHGWT GRGGNQLHGF QVRRMITEYC DRLRRDGVMT PAQQMQIEAL 

       370        380        390        400        410 
GDQTQQFKRD KLEAWALEDD QYNRAHPNST MFRTKPFTNA QWGRGNTAAT SAAIAALI 

« Hide

References

[1]"The S2 gene nucleotide sequences of prototype strains of the three reovirus serotypes: characterization of reovirus core protein sigma 2."
Dermody T.S., Schiff L.A., Nibert M.L., Coombs K.M., Fields B.N.
J. Virol. 65:5721-5731(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L19775 Genomic RNA. Translation: AAA47248.1.
PIRFOXRJS. B41306.

3D structure databases

ProteinModelPortalP32922.
SMRP32922. Positions 2-418.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR004317. Sigma_1_2_reovir.
[Graphical view]
PfamPF03084. Sigma_1_2. 1 hit.
[Graphical view]
ProDomPD004419. Sigma_1_2_reovir. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetSearch...

Entry information

Entry nameSIGM2_REOVJ
AccessionPrimary (citable) accession number: P32922
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: October 16, 2013
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families