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Protein

Protein SSO1

Gene

SSO1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Required for vesicle fusion with the plasma membrane.

GO - Molecular functioni

  • phosphatidic acid binding Source: SGD
  • phosphatidylinositol-3,4-bisphosphate binding Source: SGD
  • phosphatidylinositol-3,5-bisphosphate binding Source: SGD
  • phosphatidylinositol-4,5-bisphosphate binding Source: SGD
  • SNAP receptor activity Source: SGD
  • SNARE binding Source: GO_Central

GO - Biological processi

  • ascospore formation Source: SGD
  • ascospore-type prospore assembly Source: SGD
  • intracellular protein transport Source: GO_Central
  • vesicle docking Source: GO_Central
  • vesicle fusion Source: SGD
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-34119-MONOMER.
ReactomeiR-SCE-114516. Disinhibition of SNARE formation.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein SSO1
Gene namesi
Name:SSO1
Ordered Locus Names:YPL232W
ORF Names:P1405
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XVI

Organism-specific databases

EuPathDBiFungiDB:YPL232W.
SGDiS000006153. SSO1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 265CytoplasmicSequence analysisAdd BLAST265
Transmembranei266 – 287Helical; Anchor for type IV membrane proteinSequence analysisAdd BLAST22
Topological domaini288 – 290ExtracellularSequence analysis3

GO - Cellular componenti

  • endomembrane system Source: GO_Central
  • fungal-type vacuole membrane Source: SGD
  • integral component of membrane Source: GO_Central
  • plasma membrane Source: SGD
  • prospore membrane Source: SGD
  • SNARE complex Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002102741 – 290Protein SSO1Add BLAST290

Proteomic databases

MaxQBiP32867.
PRIDEiP32867.

PTM databases

iPTMnetiP32867.
SwissPalmiP32867.

Interactioni

GO - Molecular functioni

  • SNAP receptor activity Source: SGD
  • SNARE binding Source: GO_Central

Protein-protein interaction databases

BioGridi35930. 91 interactors.
DIPiDIP-2494N.
IntActiP32867. 2 interactors.
MINTiMINT-4505526.

Structurei

Secondary structure

1290
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi31 – 64Combined sources34
Helixi70 – 104Combined sources35
Turni105 – 107Combined sources3
Helixi109 – 151Combined sources43
Helixi157 – 163Combined sources7
Helixi166 – 176Combined sources11
Helixi190 – 256Combined sources67

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1FIOX-ray2.10A31-225[»]
3B5NX-ray1.60B/F/J189-257[»]
ProteinModelPortaliP32867.
SMRiP32867.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP32867.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini190 – 252t-SNARE coiled-coil homologyPROSITE-ProRule annotationAdd BLAST63

Sequence similaritiesi

Belongs to the syntaxin family.Curated
Contains 1 t-SNARE coiled-coil homology domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00760000119200.
HOGENOMiHOG000246774.
InParanoidiP32867.
KOiK08486.
OMAiDFVGFMN.
OrthoDBiEOG092C42X0.

Family and domain databases

InterProiIPR006012. Syntaxin/epimorphin_CS.
IPR006011. Syntaxin_N.
IPR010989. t-SNARE.
IPR000727. T_SNARE_dom.
[Graphical view]
PfamiPF05739. SNARE. 1 hit.
PF00804. Syntaxin. 1 hit.
[Graphical view]
SMARTiSM00503. SynN. 1 hit.
SM00397. t_SNARE. 1 hit.
[Graphical view]
SUPFAMiSSF47661. SSF47661. 1 hit.
PROSITEiPS00914. SYNTAXIN. 1 hit.
PS50192. T_SNARE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P32867-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYNNPYQLE TPFEESYELD EGSSAIGAEG HDFVGFMNKI SQINRDLDKY
60 70 80 90 100
DHTINQVDSL HKRLLTEVNE EQASHLRHSL DNFVAQATDL QFKLKNEIKS
110 120 130 140 150
AQRDGIHDTN KQAQAENSRQ RFLKLIQDYR IVDSNYKEEN KEQAKRQYMI
160 170 180 190 200
IQPEATEDEV EAAISDVGGQ QIFSQALLNA NRRGEAKTAL AEVQARHQEL
210 220 230 240 250
LKLEKSMAEL TQLFNDMEEL VIEQQENVDV IDKNVEDAQL DVEQGVGHTD
260 270 280 290
KAVKSARKAR KNKIRCWLIV FAIIVVVVVV VVVPAVVKTR
Length:290
Mass (Da):33,106
Last modified:February 1, 1995 - v2
Checksum:i6E4C6D35C3CD9D94
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti97E → G no nucleotide entry (PubMed:2900835).Curated1
Sequence conflicti105G → V no nucleotide entry (PubMed:2900835).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X67729 mRNA. Translation: CAA47959.1.
X76890 Genomic DNA. Translation: CAA54217.1.
X94561 Genomic DNA. Translation: CAA64255.1.
Z73588 Genomic DNA. Translation: CAA97949.1.
J03936 Genomic DNA. No translation available.
BK006949 Genomic DNA. Translation: DAA11204.1.
PIRiS39569.
RefSeqiNP_015092.1. NM_001184046.1.

Genome annotation databases

EnsemblFungiiYPL232W; YPL232W; YPL232W.
GeneIDi855844.
KEGGisce:YPL232W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X67729 mRNA. Translation: CAA47959.1.
X76890 Genomic DNA. Translation: CAA54217.1.
X94561 Genomic DNA. Translation: CAA64255.1.
Z73588 Genomic DNA. Translation: CAA97949.1.
J03936 Genomic DNA. No translation available.
BK006949 Genomic DNA. Translation: DAA11204.1.
PIRiS39569.
RefSeqiNP_015092.1. NM_001184046.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1FIOX-ray2.10A31-225[»]
3B5NX-ray1.60B/F/J189-257[»]
ProteinModelPortaliP32867.
SMRiP32867.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi35930. 91 interactors.
DIPiDIP-2494N.
IntActiP32867. 2 interactors.
MINTiMINT-4505526.

PTM databases

iPTMnetiP32867.
SwissPalmiP32867.

Proteomic databases

MaxQBiP32867.
PRIDEiP32867.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYPL232W; YPL232W; YPL232W.
GeneIDi855844.
KEGGisce:YPL232W.

Organism-specific databases

EuPathDBiFungiDB:YPL232W.
SGDiS000006153. SSO1.

Phylogenomic databases

GeneTreeiENSGT00760000119200.
HOGENOMiHOG000246774.
InParanoidiP32867.
KOiK08486.
OMAiDFVGFMN.
OrthoDBiEOG092C42X0.

Enzyme and pathway databases

BioCyciYEAST:G3O-34119-MONOMER.
ReactomeiR-SCE-114516. Disinhibition of SNARE formation.

Miscellaneous databases

EvolutionaryTraceiP32867.
PROiP32867.

Family and domain databases

InterProiIPR006012. Syntaxin/epimorphin_CS.
IPR006011. Syntaxin_N.
IPR010989. t-SNARE.
IPR000727. T_SNARE_dom.
[Graphical view]
PfamiPF05739. SNARE. 1 hit.
PF00804. Syntaxin. 1 hit.
[Graphical view]
SMARTiSM00503. SynN. 1 hit.
SM00397. t_SNARE. 1 hit.
[Graphical view]
SUPFAMiSSF47661. SSF47661. 1 hit.
PROSITEiPS00914. SYNTAXIN. 1 hit.
PS50192. T_SNARE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSSO1_YEAST
AccessioniPrimary (citable) accession number: P32867
Secondary accession number(s): D6W3D8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: February 1, 1995
Last modified: November 2, 2016
This is version 141 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 450 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome XVI
    Yeast (Saccharomyces cerevisiae) chromosome XVI: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.