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P32805 (FZF1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 119. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Zinc finger protein FZF1
Alternative name(s):
Sulfite resistance protein 1
Gene names
Name:FZF1
Synonyms:SUL1
Ordered Locus Names:YGL254W
ORF Names:NCR299
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length299 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

May function as a transcription factor.

Subcellular location

Nucleus Potential.

Miscellaneous

Present with 2120 molecules/cell in log phase SD medium.

Sequence similarities

Contains 5 C2H2-type zinc fingers.

Sequence caution

The sequence CAA47998.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 299299Zinc finger protein FZF1
PRO_0000046805

Regions

Zinc finger12 – 3625C2H2-type 1
Zinc finger42 – 6625C2H2-type 2
Zinc finger72 – 9423C2H2-type 3
Zinc finger155 – 17925C2H2-type 4
Zinc finger246 – 27126C2H2-type 5
Motif96 – 10712Nuclear localization signal Potential

Natural variations

Natural variant1101G → E in strain: Sgu52E and Sgu52F.
Natural variant1201N → D in strain: MMW1-15h2, MMW1-2h2, Sgu52E and Sgu52F.
Natural variant2281V → I in strain: MMW1-15h2, MMW1-2h2, Sgu52E and Sgu52F.
Natural variant2381D → N in strain: MMW1-15h2 and MMW1-2h2.

Experimental info

Sequence conflict1801H → D in CAA54996. Ref.2
Sequence conflict2351T → W Ref.1
Sequence conflict2461N → Y in CAA54996. Ref.2

Sequences

Sequence LengthMass (Da)Tools
P32805 [UniParc].

Last modified October 1, 1996. Version 2.
Checksum: A4E7257F012B32FF

FASTA29933,994
        10         20         30         40         50         60 
MTDIGRTKSR NYKCSFDGCE KVYNRPSLLQ QHQNSHTNQK PYHCDEPGCG KKFIRPCHLR 

        70         80         90        100        110        120 
VHKWTHSQIK PKACTLCQKR FVTNQQLRRH LNSHERKSKL ASRIDRKHEG VNANVKAELN 

       130        140        150        160        170        180 
GKEGGFDPKL PSGSPMCGEE FSQGHLPGYD DMQVLQCPYK SCQKVTSFND DLINHMLQHH 

       190        200        210        220        230        240 
IASKLVVPSG DPSLKESLPT SEKSSSTDTT SIPQLSFSTT GTSSSESVDS TTAQTPTDPE 

       250        260        270        280        290 
SYWSDNRCKH SDCQELSPFA SVFDLIDHYD HTHAFIPETL VKYSYIHLYK PSVWDLFEY 

« Hide

References

« Hide 'large scale' references
[1]"Identification of a gene encoding a novel zinc finger protein in Saccharomyces cerevisiae."
Breitwieser W., Price C., Schuster T.
Yeast 9:551-556(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 200060 / W303.
[2]"Cloning and characterization of a sulphite-resistance gene of Saccharomyces cerevisiae."
Casalone E., Colella C.M., Daly S., Fontana S., Torricelli I., Polsinelli M.
Yeast 10:1101-1110(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]"Population structure and gene evolution in Saccharomyces cerevisiae."
Aa E., Townsend J.P., Adams R.I., Nielsen K.M., Taylor J.W.
FEMS Yeast Res. 6:702-715(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 76625 / YPH499, MMW1-15, MMW1-15h2, MMW1-2, MMW1-2h2, Sgu52E, Sgu52F, YPS396, YPS400, YPS598, YPS600, YPS602, YPS604, YPS606, YPS608 and YPS610.
[4]"Sequence of a 39,411 bp DNA fragment covering the left end of chromosome VII of Saccharomyces cerevisiae."
Coissac E., Maillier E., Robineau S., Netter P.
Yeast 12:1555-1562(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 96604 / S288c / FY1679.
[5]"The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E. expand/collapse author list , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[6]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[7]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X67787 Genomic DNA. Translation: CAA47998.1. Sequence problems.
X78104 Genomic DNA. Translation: CAA54996.1.
AY949902 Genomic DNA. Translation: AAY27304.1.
AY949903 Genomic DNA. Translation: AAY27305.1.
AY949905 Genomic DNA. Translation: AAY27307.1.
AY949906 Genomic DNA. Translation: AAY27308.1.
AY949908 Genomic DNA. Translation: AAY27310.1.
AY949909 Genomic DNA. Translation: AAY27311.1.
AY949910 Genomic DNA. Translation: AAY27312.1.
AY949911 Genomic DNA. Translation: AAY27313.1.
AY949912 Genomic DNA. Translation: AAY27314.1.
AY949913 Genomic DNA. Translation: AAY27315.1.
AY949914 Genomic DNA. Translation: AAY27316.1.
AY949915 Genomic DNA. Translation: AAY27317.1.
AY949916 Genomic DNA. Translation: AAY27318.1.
AY949917 Genomic DNA. Translation: AAY27319.1.
AY949918 Genomic DNA. Translation: AAY27320.1.
AY949919 Genomic DNA. Translation: AAY27321.1.
X94357 Genomic DNA. Translation: CAA64133.1.
Z72776 Genomic DNA. Translation: CAA96974.1.
BK006941 Genomic DNA. Translation: DAA07865.1.
PIRS61607.
RefSeqNP_011260.1. NM_001181120.1.

3D structure databases

ProteinModelPortalP32805.
SMRP32805. Positions 6-179.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid33025. 25 interactions.
DIPDIP-1324N.
IntActP32805. 8 interactions.
MINTMINT-402589.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYGL254W; YGL254W; YGL254W.
GeneID852638.
KEGGsce:YGL254W.

Organism-specific databases

CYGDYGL254w.
SGDS000003223. FZF1.

Phylogenomic databases

GeneTreeENSGT00550000074555.
OMARVHKWTH.
OrthoDBEOG751NSX.

Enzyme and pathway databases

BioCycYEAST:G3O-30723-MONOMER.

Gene expression databases

GenevestigatorP32805.

Family and domain databases

Gene3D3.30.160.60. 3 hits.
InterProIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamPF00096. zf-C2H2. 2 hits.
[Graphical view]
SMARTSM00355. ZnF_C2H2. 5 hits.
[Graphical view]
PROSITEPS00028. ZINC_FINGER_C2H2_1. 3 hits.
PS50157. ZINC_FINGER_C2H2_2. 3 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio971885.

Entry information

Entry nameFZF1_YEAST
AccessionPrimary (citable) accession number: P32805
Secondary accession number(s): D6VV81 expand/collapse secondary AC list , Q2VQB9, Q2VQC2, Q2VQC3
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1996
Last modified: April 16, 2014
This is version 119 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome VII

Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families