P32800 (PEX2_YEAST) Reviewed, UniProtKB/Swiss-Prot
Last modified
December 14, 2011.
Version 100.
History...
Names·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Peroxisomal biogenesis factor 2 Alternative name(s): Peroxin-2 Peroxisomal protein PAS5 Protein CRT1 | ||||||||
| Gene names |
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| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | ||||||||
| Taxonomic identifier | 559292 [NCBI] | ||||||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces |
Protein attributes
| Sequence length | 271 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Function | Required for the import of several proteins into peroxisomes. |
| Subcellular location | |
| Miscellaneous | Present with 339 molecules/cell in log phase SD medium. Ref.5 |
| Sequence similarities | Belongs to the pex2/pex10/pex12 family. Contains 1 RING-type zinc finger. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Peroxisome |
| Coding sequence diversity | Alternative initiation |
| Domain | Zinc-finger |
| Ligand | Metal-binding Zinc |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | protein import into peroxisome matrix Inferred from mutant phenotype. Source: SGD |
| Cellular component | peroxisomal membrane Inferred from direct assay. Source: SGD |
| Molecular function | metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW ubiquitin-protein ligase activityInferred from direct assay. Source: SGD |
| Complete GO annotation... | |
Alternative products
| This entry describes 2 isoforms produced by alternative initiation. [Align] [Select] | ||||||
| Isoform Long (identifier: P32800-1) This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. | ||||||
| Isoform Short (identifier: P32800-2) The sequence of this isoform differs from the canonical sequence as follows: 1-46: Missing. | ||||||
| Note: No experimental confirmation available. |
Sequence annotation (Features)
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Independent regulation of full-length and 5'-truncated PAS5 mRNAs in Saccharomyces cerevisiae." Liu Y., Gu K.L., Dieckmann C.L. Yeast 12:135-143(1996) [PubMed: 8686377] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
| [2] | "Sequence analysis of a 40.2 kb DNA fragment located near the left telomere of yeast chromosome X." Vandenbol M., Durand P., Bolle P.-A., Dion C., Portetelle D., Hilger F. Yeast 10:1657-1662(1994) [PubMed: 7725802] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c. |
| [3] | "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X." Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. Karpfinger-Hartl L.EMBO J. 15:2031-2049(1996) [PubMed: 8641269] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204508 / S288c. |
| [4] | Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c. |
| [5] | "Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS]. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | M86538 Genomic DNA. Translation: AAB36836.1. Z34098 Genomic DNA. Translation: CAA84000.1. Z49486 Genomic DNA. Translation: CAA89508.1. BK006943 Genomic DNA. Translation: DAA08600.1. |
| PIR | S27422. |
| RefSeq | NP_012325.1. NM_001181643.1. |
3D structure databases | |
| ProteinModelPortal | P32800. |
| SMR | P32800. Positions 217-263. |
| ModBase | Search... |
Protein-protein interaction databases | |
| DIP | DIP-4760N. |
| MINT | MINT-551616. |
| STRING | P32800. |
Proteomic databases | |
| PeptideAtlas | P32800. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblFungi | YJL210W; YJL210W; YJL210W. |
| GeneID | 853219. |
| KEGG | sce:YJL210W. |
| NMPDR | fig|4932.3.peg.3288. |
Organism-specific databases | |
| CYGD | YJL210w. |
| SGD | S000003746. PEX2. |
Phylogenomic databases | |
| eggNOG | fuNOG10005. |
| HOGENOM | HBG202179. |
| OMA | MSRVAQL. |
| OrthoDB | EOG466ZWM. |
Gene expression databases | |
| ArrayExpress | P32800. |
| Genevestigator | P32800. |
| GermOnline | YJL210W. Saccharomyces cerevisiae. |
Family and domain databases | |
| InterPro | IPR006845. Pex_N. IPR013083. Znf_RING/FYVE/PHD. [Graphical view] |
| Gene3D | G3DSA:3.30.40.10. Znf_RING/FYVE/PHD. 1 hit. |
| KO | K06664. |
| Pfam | PF04757. Pex2_Pex12. 1 hit. [Graphical view] |
| PROSITE | PS00518. ZF_RING_1. False negative. PS50089. ZF_RING_2. False negative. [Graphical view] |
| ProtoNet | Search... |
Other | |
| NextBio | 973416. |
Entry information
| Entry name | PEX2_YEAST | ||||||||
| Accession | Primary (citable) accession number: P32800 Secondary accession number(s): D6VVY4 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Fungal Protein Annotation Program | ||||||||
Relevant documents
| Yeast Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD |
| Yeast chromosome X Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with