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Protein

Mitochondrial genome maintenance protein MGM101

Gene

MGM101

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Performs an essential function in the repair of oxidatively damaged mtDNA that is required for the maintenance of the mitochondrial genome. Binds to DNA.1 Publication

GO - Molecular functioni

  • single-stranded DNA binding Source: SGD

GO - Biological processi

  • DNA repair Source: SGD
  • DNA strand renaturation Source: SGD
  • interstrand cross-link repair Source: SGD
  • mitochondrial genome maintenance Source: SGD
  • recombinational repair Source: SGD

Keywordsi

Molecular functionDNA-binding
Biological processDNA damage, DNA repair

Enzyme and pathway databases

BioCyciYEAST:G3O-31758-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial genome maintenance protein MGM101
Gene namesi
Name:MGM101
Synonyms:MGM9
Ordered Locus Names:YJR144W
ORF Names:J2181
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome X

Organism-specific databases

EuPathDBiFungiDB:YJR144W
SGDiS000003905 MGM101

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion, Mitochondrion nucleoid

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 30MitochondrionSequence analysisAdd BLAST30
ChainiPRO_000002171931 – 269Mitochondrial genome maintenance protein MGM101Add BLAST239

Proteomic databases

MaxQBiP32787
PaxDbiP32787
PRIDEiP32787

2D gel databases

UCD-2DPAGEiP32787

PTM databases

iPTMnetiP32787

Interactioni

Protein-protein interaction databases

BioGridi33900, 255 interactors
DIPiDIP-5044N
IntActiP32787, 20 interactors
MINTiP32787
STRINGi4932.YJR144W

Structurei

3D structure databases

ProteinModelPortaliP32787
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MGM101 family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

HOGENOMiHOG000214596
InParanoidiP32787
OrthoDBiEOG092C4BK0

Family and domain databases

InterProiView protein in InterPro
IPR009446 Mgm101
PANTHERiPTHR31404 PTHR31404, 1 hit
PfamiView protein in Pfam
PF06420 Mgm101p, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P32787-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSIFKVRGC VSHAAQFCQK RTVVSTGTSN TATAGAVRKS FNSTETKPVF
60 70 80 90 100
ATKSEAGNGS HMKEYSSGIN SKLGGTPLET RSTADDSLNN SYKQVKGDID
110 120 130 140 150
WYTSWYGLGM KPFEAKVQKD LIEPLDPKDI EIKPDGLIYL PEIKYRRILN
160 170 180 190 200
KAFGAGGWGL VPRSQTIVTS KLVTREYGLI CHGQLISVAR GEQDYFNEAG
210 220 230 240 250
IPTATEGCKS NALMRCCKDL GVGSELWDPV FIKKFKVDHC TEKFVEHVTT
260
KRKKKIWLRK DRQVEYPYK
Length:269
Mass (Da):30,091
Last modified:October 1, 1993 - v1
Checksum:iE14C17F2E837D6F0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X68482 Genomic DNA Translation: CAA48502.1
Z49644 Genomic DNA Translation: CAA89677.1
BK006943 Genomic DNA Translation: DAA08929.1
PIRiS34849
RefSeqiNP_012678.1, NM_001181802.1

Genome annotation databases

EnsemblFungiiYJR144W; YJR144W; YJR144W
GeneIDi853609
KEGGisce:YJR144W

Similar proteinsi

Entry informationi

Entry nameiMG101_YEAST
AccessioniPrimary (citable) accession number: P32787
Secondary accession number(s): D6VWW3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: March 28, 2018
This is version 137 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health