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P32782

- PDE1_CANAX

UniProt

P32782 - PDE1_CANAX

Protein

3',5'-cyclic-nucleotide phosphodiesterase

Gene

PDE1

Organism
Candida albicans (Yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 52 (01 Oct 2014)
      Sequence version 2 (01 Nov 1995)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate.

    GO - Molecular functioni

    1. 3',5'-cyclic-AMP phosphodiesterase activity Source: InterPro

    GO - Biological processi

    1. cAMP catabolic process Source: InterPro

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Ligandi

    cAMP

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    3',5'-cyclic-nucleotide phosphodiesterase (EC:3.1.4.17)
    Short name:
    3':5'-CNP
    Short name:
    PDEase
    Gene namesi
    Name:PDE1
    OrganismiCandida albicans (Yeast)
    Taxonomic identifieri5476 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 4264263',5'-cyclic-nucleotide phosphodiesterasePRO_0000206789Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP32782.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG5212.

    Family and domain databases

    Gene3Di3.60.15.10. 1 hit.
    InterProiIPR001279. Beta-lactamas-like.
    IPR024225. cAMP-PdiesteraseII_CS.
    IPR000396. Pdiesterase2.
    [Graphical view]
    PfamiPF02112. PDEase_II. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000962. Cyc_nuc_PDEase. 1 hit.
    PRINTSiPR00388. PDIESTERASE2.
    SUPFAMiSSF56281. SSF56281. 2 hits.
    PROSITEiPS00607. PDEASE_II. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P32782-1 [UniParc]FASTAAdd to Basket

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    MSFEITILGS SGGPLEGSTC SILLKPANIS YHDIINDNLP DQVLCIDAGS    50
    GMGKLTEIIH QETTTKTSYC NFLQYYPDCE TVSYYYHPNV TITTPFSNFQ 100
    PGRPILHTQN IFNNLQNYLI SHSHLDHVCS VVINSAGFNK NMSNKILYGS 150
    HYTINAMQQH LFNGKVWPNM PSFKIVNLNY LESNRSERIG IYTVKMFDLS 200
    HGEFNKLTED KEDAQHHSNS NSNSNNIWGK RYDRRRSSIT TIPQNTSGLI 250
    IKNSEALNHH YLSSAFLITL EVPCTTKEPP PSILVFGDFE SDLTSKLSRN 300
    LFIWKSIASL ILRNQLKAIV LECSNCKEIA ANELYGHLTP KLLIYELKQL 350
    EHECKQLDTA TTSTEQPLLG LNVIVNHVKE PIADPNQESQ LHDPRKRILA 400
    ELNKLNEIEK LGCNISIALS GTSIIV 426
    Length:426
    Mass (Da):47,982
    Last modified:November 1, 1995 - v2
    Checksum:iA6F4581F2D2CEC75
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L12045 Genomic DNA. Translation: AAA34355.2.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L12045 Genomic DNA. Translation: AAA34355.2 .

    3D structure databases

    ProteinModelPortali P32782.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    eggNOGi COG5212.

    Family and domain databases

    Gene3Di 3.60.15.10. 1 hit.
    InterProi IPR001279. Beta-lactamas-like.
    IPR024225. cAMP-PdiesteraseII_CS.
    IPR000396. Pdiesterase2.
    [Graphical view ]
    Pfami PF02112. PDEase_II. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000962. Cyc_nuc_PDEase. 1 hit.
    PRINTSi PR00388. PDIESTERASE2.
    SUPFAMi SSF56281. SSF56281. 2 hits.
    PROSITEi PS00607. PDEASE_II. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "A Candida albicans cyclic nucleotide phosphodiesterase: cloning and expression in Saccharomyces cerevisiae and biochemical characterization of the recombinant enzyme."
      Hoyer L.L., Cieslinski L.B., McLaughlin M.M., Torphy T.J., Livi G.P., Shatzman A.R.
      Microbiology 140:1533-1542(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 11651 / B792 / 171D.

    Entry informationi

    Entry nameiPDE1_CANAX
    AccessioniPrimary (citable) accession number: P32782
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1993
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 52 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3