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P32782

- PDE1_CANAX

UniProt

P32782 - PDE1_CANAX

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Protein

3',5'-cyclic-nucleotide phosphodiesterase

Gene

PDE1

Organism
Candida albicans (Yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate.

GO - Molecular functioni

  1. 3',5'-cyclic-AMP phosphodiesterase activity Source: InterPro

GO - Biological processi

  1. cAMP catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

cAMP

Names & Taxonomyi

Protein namesi
Recommended name:
3',5'-cyclic-nucleotide phosphodiesterase (EC:3.1.4.17)
Short name:
3':5'-CNP
Short name:
PDEase
Gene namesi
Name:PDE1
OrganismiCandida albicans (Yeast)
Taxonomic identifieri5476 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 4264263',5'-cyclic-nucleotide phosphodiesterasePRO_0000206789Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP32782.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG5212.

Family and domain databases

Gene3Di3.60.15.10. 1 hit.
InterProiIPR001279. Beta-lactamas-like.
IPR024225. cAMP-PdiesteraseII_CS.
IPR000396. Pdiesterase2.
[Graphical view]
PfamiPF02112. PDEase_II. 1 hit.
[Graphical view]
PIRSFiPIRSF000962. Cyc_nuc_PDEase. 1 hit.
PRINTSiPR00388. PDIESTERASE2.
SUPFAMiSSF56281. SSF56281. 2 hits.
PROSITEiPS00607. PDEASE_II. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P32782-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSFEITILGS SGGPLEGSTC SILLKPANIS YHDIINDNLP DQVLCIDAGS
60 70 80 90 100
GMGKLTEIIH QETTTKTSYC NFLQYYPDCE TVSYYYHPNV TITTPFSNFQ
110 120 130 140 150
PGRPILHTQN IFNNLQNYLI SHSHLDHVCS VVINSAGFNK NMSNKILYGS
160 170 180 190 200
HYTINAMQQH LFNGKVWPNM PSFKIVNLNY LESNRSERIG IYTVKMFDLS
210 220 230 240 250
HGEFNKLTED KEDAQHHSNS NSNSNNIWGK RYDRRRSSIT TIPQNTSGLI
260 270 280 290 300
IKNSEALNHH YLSSAFLITL EVPCTTKEPP PSILVFGDFE SDLTSKLSRN
310 320 330 340 350
LFIWKSIASL ILRNQLKAIV LECSNCKEIA ANELYGHLTP KLLIYELKQL
360 370 380 390 400
EHECKQLDTA TTSTEQPLLG LNVIVNHVKE PIADPNQESQ LHDPRKRILA
410 420
ELNKLNEIEK LGCNISIALS GTSIIV
Length:426
Mass (Da):47,982
Last modified:November 1, 1995 - v2
Checksum:iA6F4581F2D2CEC75
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L12045 Genomic DNA. Translation: AAA34355.2.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L12045 Genomic DNA. Translation: AAA34355.2 .

3D structure databases

ProteinModelPortali P32782.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

eggNOGi COG5212.

Family and domain databases

Gene3Di 3.60.15.10. 1 hit.
InterProi IPR001279. Beta-lactamas-like.
IPR024225. cAMP-PdiesteraseII_CS.
IPR000396. Pdiesterase2.
[Graphical view ]
Pfami PF02112. PDEase_II. 1 hit.
[Graphical view ]
PIRSFi PIRSF000962. Cyc_nuc_PDEase. 1 hit.
PRINTSi PR00388. PDIESTERASE2.
SUPFAMi SSF56281. SSF56281. 2 hits.
PROSITEi PS00607. PDEASE_II. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "A Candida albicans cyclic nucleotide phosphodiesterase: cloning and expression in Saccharomyces cerevisiae and biochemical characterization of the recombinant enzyme."
    Hoyer L.L., Cieslinski L.B., McLaughlin M.M., Torphy T.J., Livi G.P., Shatzman A.R.
    Microbiology 140:1533-1542(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 11651 / B792 / 171D.

Entry informationi

Entry nameiPDE1_CANAX
AccessioniPrimary (citable) accession number: P32782
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: November 1, 1995
Last modified: October 29, 2014
This is version 53 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3