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P32782

- PDE1_CANAX

UniProt

P32782 - PDE1_CANAX

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Protein
3',5'-cyclic-nucleotide phosphodiesterase
Gene
PDE1
Organism
Candida albicans (Yeast)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate.

GO - Molecular functioni

  1. 3',5'-cyclic-AMP phosphodiesterase activity Source: InterPro

GO - Biological processi

  1. cAMP catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

cAMP

Names & Taxonomyi

Protein namesi
Recommended name:
3',5'-cyclic-nucleotide phosphodiesterase (EC:3.1.4.17)
Short name:
3':5'-CNP
Short name:
PDEase
Gene namesi
Name:PDE1
OrganismiCandida albicans (Yeast)
Taxonomic identifieri5476 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 4264263',5'-cyclic-nucleotide phosphodiesterase
PRO_0000206789Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP32782.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG5212.

Family and domain databases

Gene3Di3.60.15.10. 1 hit.
InterProiIPR001279. Beta-lactamas-like.
IPR024225. cAMP-PdiesteraseII_CS.
IPR000396. Pdiesterase2.
[Graphical view]
PfamiPF02112. PDEase_II. 1 hit.
[Graphical view]
PIRSFiPIRSF000962. Cyc_nuc_PDEase. 1 hit.
PRINTSiPR00388. PDIESTERASE2.
SUPFAMiSSF56281. SSF56281. 2 hits.
PROSITEiPS00607. PDEASE_II. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P32782-1 [UniParc]FASTAAdd to Basket

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MSFEITILGS SGGPLEGSTC SILLKPANIS YHDIINDNLP DQVLCIDAGS    50
GMGKLTEIIH QETTTKTSYC NFLQYYPDCE TVSYYYHPNV TITTPFSNFQ 100
PGRPILHTQN IFNNLQNYLI SHSHLDHVCS VVINSAGFNK NMSNKILYGS 150
HYTINAMQQH LFNGKVWPNM PSFKIVNLNY LESNRSERIG IYTVKMFDLS 200
HGEFNKLTED KEDAQHHSNS NSNSNNIWGK RYDRRRSSIT TIPQNTSGLI 250
IKNSEALNHH YLSSAFLITL EVPCTTKEPP PSILVFGDFE SDLTSKLSRN 300
LFIWKSIASL ILRNQLKAIV LECSNCKEIA ANELYGHLTP KLLIYELKQL 350
EHECKQLDTA TTSTEQPLLG LNVIVNHVKE PIADPNQESQ LHDPRKRILA 400
ELNKLNEIEK LGCNISIALS GTSIIV 426
Length:426
Mass (Da):47,982
Last modified:November 1, 1995 - v2
Checksum:iA6F4581F2D2CEC75
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L12045 Genomic DNA. Translation: AAA34355.2.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L12045 Genomic DNA. Translation: AAA34355.2 .

3D structure databases

ProteinModelPortali P32782.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

eggNOGi COG5212.

Family and domain databases

Gene3Di 3.60.15.10. 1 hit.
InterProi IPR001279. Beta-lactamas-like.
IPR024225. cAMP-PdiesteraseII_CS.
IPR000396. Pdiesterase2.
[Graphical view ]
Pfami PF02112. PDEase_II. 1 hit.
[Graphical view ]
PIRSFi PIRSF000962. Cyc_nuc_PDEase. 1 hit.
PRINTSi PR00388. PDIESTERASE2.
SUPFAMi SSF56281. SSF56281. 2 hits.
PROSITEi PS00607. PDEASE_II. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "A Candida albicans cyclic nucleotide phosphodiesterase: cloning and expression in Saccharomyces cerevisiae and biochemical characterization of the recombinant enzyme."
    Hoyer L.L., Cieslinski L.B., McLaughlin M.M., Torphy T.J., Livi G.P., Shatzman A.R.
    Microbiology 140:1533-1542(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 11651 / B792 / 171D.

Entry informationi

Entry nameiPDE1_CANAX
AccessioniPrimary (citable) accession number: P32782
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: November 1, 1995
Last modified: April 16, 2014
This is version 51 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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