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Reviewed, UniProtKB/Swiss-Prot P32782 (PDE1_CANAL)

Last modified January 20, 2009. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    3',5'-cyclic-nucleotide phosphodiesterase
      Short name=PDEase
      Short name=3':5'-CNP
    EC=3.1.4.17
Gene names
Name: PDE1
OrganismCandida albicans (Yeast)
Taxonomic identifier5476 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida

Protein attributes

Sequence length426 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

Nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate.

Sequence similarities

Belongs to the cAMP phosphodiesterase class-II family.

Ontologies

Keywords
   LigandcAMP
   Molecular functionHydrolase
Gene Ontology (GO)
   Biological processcAMP catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular function3',5'-cyclic-AMP phosphodiesterase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4264263',5'-cyclic-nucleotide phosphodiesterase
PRO_0000206789

Sequences

Sequence LengthMass (Da)Tools
P32782-1 [UniParc].

Last modified November 1, 1995. Version 2.
Checksum: A6F4581F2D2CEC75

FASTA42647,982
        10         20         30         40         50         60 
MSFEITILGS SGGPLEGSTC SILLKPANIS YHDIINDNLP DQVLCIDAGS GMGKLTEIIH 

        70         80         90        100        110        120 
QETTTKTSYC NFLQYYPDCE TVSYYYHPNV TITTPFSNFQ PGRPILHTQN IFNNLQNYLI 

       130        140        150        160        170        180 
SHSHLDHVCS VVINSAGFNK NMSNKILYGS HYTINAMQQH LFNGKVWPNM PSFKIVNLNY 

       190        200        210        220        230        240 
LESNRSERIG IYTVKMFDLS HGEFNKLTED KEDAQHHSNS NSNSNNIWGK RYDRRRSSIT 

       250        260        270        280        290        300 
TIPQNTSGLI IKNSEALNHH YLSSAFLITL EVPCTTKEPP PSILVFGDFE SDLTSKLSRN 

       310        320        330        340        350        360 
LFIWKSIASL ILRNQLKAIV LECSNCKEIA ANELYGHLTP KLLIYELKQL EHECKQLDTA 

       370        380        390        400        410        420 
TTSTEQPLLG LNVIVNHVKE PIADPNQESQ LHDPRKRILA ELNKLNEIEK LGCNISIALS 


GTSIIV 

« Hide

References

[1]"A Candida albicans cyclic nucleotide phosphodiesterase: cloning and expression in Saccharomyces cerevisiae and biochemical characterization of the recombinant enzyme."
Hoyer L.L., Cieslinski L.B., McLaughlin M.M., Torphy T.J., Livi G.P., Shatzman A.R.
Microbiology 140:1533-1542(1994) [PubMed: 8075796] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 11651 / B792 / 171D.

Cross-references

Sequence databases

L12045 Genomic DNA. Translation: AAA34355.2.

3D structure databases

ModBaseSearch...

Enzyme and pathway databases

BRENDA3.1.4.17. 1124.

Family and domain databases

InterProIPR000396. Pdiesterase2.
[Graphical view]
PfamPF02112. PDEase_II. 1 hit.
[Graphical view]
PIRSFPIRSF000962. Cyc_nuc_PDEase. 1 hit.
PRINTSPR00388. PDIESTERASE2.
ProDomPD010003. Pdiesterase2_lac. 2 hits.
[Graphical view] [Entries sharing at least one domain]
PROSITEPS00607. PDEASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePDE1_CANAL
AccessionPrimary (citable) accession number: P32782
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: November 1, 1995
Last modified: January 20, 2009
This is version 37 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

Relevant documents

Candida albicans

Candida albicans: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents