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P32770 (NRP1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 122. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Asparagine-rich protein
Short name=Protein ARP
Gene names
Name:NRP1
Synonyms:ARP, ARP1
Ordered Locus Names:YDL167C
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces ›

Protein attributes

Sequence length719 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Miscellaneous

Present with 3570 molecules/cell in log phase SD medium.

Sequence similarities

Contains 2 RanBP2-type zinc fingers.

Contains 1 RRM (RNA recognition motif) domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 719719Asparagine-rich protein
PRO_0000081689

Regions

Domain226 – 32297RRM
Zinc finger355 – 38430RanBP2-type 1
Zinc finger581 – 61030RanBP2-type 2
Compositional bias490 – 56475Asn-rich

Amino acid modifications

Modified residue3451Phosphoserine Ref.5 Ref.8
Modified residue4551Phosphoserine Ref.6 Ref.7 Ref.8
Modified residue6341Phosphoserine Ref.8

Experimental info

Sequence conflict4931I → N in CAA48159. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P32770 [UniParc].

Last modified November 1, 1997. Version 2.
Checksum: ADA9BC09FD582669

FASTA71979,299
        10         20         30         40         50         60 
MHYVVLELQV AHLPDTPKDQ CRIANIAFQI VNAETLVCHY GTNSLPSIEV NGTTKSLESA 

        70         80         90        100        110        120 
MVQLDKDIHD VIGNDDFVLV SLYSTWHIRV TLPRQARDDG FILTSYLQHP KVFDLWKEFD 

       130        140        150        160        170        180 
RWCVNHPEIL GQKKAISNNN CNTKSISINA AKNTKDLDEI VRILEVSIPT EEAGSVPEIY 

       190        200        210        220        230        240 
SLLKRTTDIL IQLHKKCTSP EDMESVLTKP YDSHTDIRAF LQEKSKILYM NNLPPDTTQS 

       250        260        270        280        290        300 
ELESWFTQYG VRPVGFWTVK NIVEDTSNVN NNWSLNNSPY VEDQDSISGF VVFQTHEEAT 

       310        320        330        340        350        360 
EVLALNGRSI LSNLANTKQP RVVEHVLELQ PSSTGVLDKA QEILSPFPQS KNKPRPGDWN 

       370        380        390        400        410        420 
CPSCGFSNFQ RRTACFRCSF PAPSNSQIHT ANSNNNVNSS RNNLNNRVNS GSSSNISNTA 

       430        440        450        460        470        480 
ANHPYGAPEF NMIANNTPAA LTYNRAHFPA ITPLSRQNSL NMAPSNSGSP IIIADHFSGN 

       490        500        510        520        530        540 
NNIAPNYRYN NNINNNNNNI NNMTNNRYNI NNNINGNGNG NGNNSNNNNN HNNNHNNNHH 

       550        560        570        580        590        600 
NGSINSNSNT NNNNNNNNGN NSNNCNSNIG MGGCGSNMPF RAGDWKCSTC TYHNFAKNVV 

       610        620        630        640        650        660 
CLRCGGPKSI SGDASETNHY IDSSTFGPAS RTPSNNNISV NTNGGSNAGR TDGNDNKGRD 

       670        680        690        700        710 
ISLMEFMSPP LSMATKSMKE GDGNGSSFNE FKSDKANVNF SNVGDNSAFG NGFNSSIRW

« Hide

References

« Hide 'large scale' references
[1]"Molecular structure and genetic regulation of SFA, a gene responsible for resistance to formaldehyde in Saccharomyces cerevisiae, and characterization of its protein product."
Wehner E.P., Rao E., Brendel M.
Mol. Gen. Genet. 237:351-358(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 38626 / AH22 / NRRL Y-12843.
[2]"The nucleotide sequence of Saccharomyces cerevisiae chromosome IV."
Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G., Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C., Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F., Delaveau T. expand/collapse author list , del Rey F., Dujon B., Eide L.G., Garcia-Cantalejo J.M., Goffeau A., Gomez-Peris A., Granotier C., Hanemann V., Hankeln T., Hoheisel J.D., Jaeger W., Jimenez A., Jonniaux J.-L., Kraemer C., Kuester H., Laamanen P., Legros Y., Louis E.J., Moeller-Rieker S., Monnet A., Moro M., Mueller-Auer S., Nussbaumer B., Paricio N., Paulin L., Perea J., Perez-Alonso M., Perez-Ortin J.E., Pohl T.M., Prydz H., Purnelle B., Rasmussen S.W., Remacha M.A., Revuelta J.L., Rieger M., Salom D., Saluz H.P., Saiz J.E., Saren A.-M., Schaefer M., Scharfe M., Schmidt E.R., Schneider C., Scholler P., Schwarz S., Soler-Mira A., Urrestarazu L.A., Verhasselt P., Vissers S., Voet M., Volckaert G., Wagner G., Wambutt R., Wedler E., Wedler H., Woelfl S., Harris D.E., Bowman S., Brown D., Churcher C.M., Connor R., Dedman K., Gentles S., Hamlin N., Hunt S., Jones L., McDonald S., Murphy L.D., Niblett D., Odell C., Oliver K., Rajandream M.A., Richards C., Shore L., Walsh S.V., Barrell B.G., Dietrich F.S., Mulligan J.T., Allen E., Araujo R., Aviles E., Berno A., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Hunicke-Smith S., Hyman R.W., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Oefner P., Oh C., Petel F.X., Roberts D., Schramm S., Schroeder M., Shogren T., Shroff N., Winant A., Yelton M.A., Botstein D., Davis R.W., Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Du Z., Favello A., Fulton L., Gattung S., Greco T., Hallsworth K., Hawkins J., Hillier L.W., Jier M., Johnson D., Johnston L., Kirsten J., Kucaba T., Langston Y., Latreille P., Le T., Mardis E., Menezes S., Miller N., Nhan M., Pauley A., Peluso D., Rifkin L., Riles L., Taich A., Trevaskis E., Vignati D., Wilcox L., Wohldman P., Vaudin M., Wilson R., Waterston R., Albermann K., Hani J., Heumann K., Kleine K., Mewes H.-W., Zollner A., Zaccaria P.
Nature 387:75-78(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[5]"Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway."
Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J., Mann M., Jensen O.N.
Mol. Cell. Proteomics 4:310-327(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-345, MASS SPECTROMETRY.
Strain: YAL6B.
[6]"Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae."
Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J., Elias J.E., Gygi S.P.
J. Proteome Res. 6:1190-1197(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-455, MASS SPECTROMETRY.
Strain: ADR376.
[7]"Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases."
Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.
Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-455, MASS SPECTROMETRY.
[8]"A multidimensional chromatography technology for in-depth phosphoproteome analysis."
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-345; SER-455 AND SER-634, MASS SPECTROMETRY.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		X68020 Genomic DNA. Translation: CAA48159.1.
Z67750 Genomic DNA. Translation: CAA91579.1.
Z74215 Genomic DNA. Translation: CAA98741.1.
BK006938 Genomic DNA. Translation: DAA11694.1.
PIRS61046.
RefSeqNP_010114.1. NM_001180227.1.

3D structure databases

ProteinModelPortalP32770.
ModBaseSearch...

Protein-protein interaction databases

DIPDIP-5159N.
IntActP32770. 13 interactions.
MINTMINT-513079.
STRING4932.YDL167C.

Proteomic databases

PaxDbP32770.
PeptideAtlasP32770.
PRIDEP32770.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYDL167C; YDL167C; YDL167C.
GeneID851387.
KEGGsce:YDL167C.

Organism-specific databases

CYGDYDL167c.
SGDS000002326. NRP1.

Phylogenomic databases

eggNOGNOG317445.
GeneTreeENSGT00700000104822.
OMAANTKQPR.
OrthoDBEOG4W11P0.

Gene expression databases

GenevestigatorP32770.
GermOnlineYDL167C. Saccharomyces cerevisiae.

Family and domain databases

Gene3D3.30.70.330. 1 hit.
InterProIPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
IPR001876. Znf_RanBP2.
[Graphical view]
PfamPF00641. zf-RanBP. 2 hits.
[Graphical view]
SMARTSM00360. RRM. 1 hit.
SM00547. ZnF_RBZ. 2 hits.
[Graphical view]
PROSITEPS50102. RRM. 1 hit.
PS01358. ZF_RANBP2_1. 2 hits.
PS50199. ZF_RANBP2_2. 2 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio968537.

Entry information

Entry nameNRP1_YEAST
AccessionPrimary (citable) accession number: P32770
Secondary accession number(s): D6VRI4, Q12228
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: November 1, 1997
Last modified: May 1, 2013
This is version 122 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Yeast chromosome IV

Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents