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Protein

Formate-dependent nitrite reductase complex subunit NrfG

Gene

nrfG

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Required for formate-dependent nitrite reduction. Not required for the biosynthesis of any of the c-type cytochromes nor for the secretion of the periplasmic cytochromes.

GO - Biological processi

  • cytochrome c-heme linkage via heme-L-cysteine Source: EcoCyc
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:EG11950-MONOMER.
ECOL316407:JW4037-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Formate-dependent nitrite reductase complex subunit NrfG
Gene namesi
Name:nrfG
Synonyms:yjcN
Ordered Locus Names:b4076, JW4037
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11950. nrfG.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001064331 – 198Formate-dependent nitrite reductase complex subunit NrfGAdd BLAST198

Proteomic databases

PaxDbiP32712.
PRIDEiP32712.

Interactioni

Protein-protein interaction databases

BioGridi4261973. 10 interactors.
IntActiP32712. 5 interactors.
STRINGi511145.b4076.

Structurei

3D structure databases

ProteinModelPortaliP32712.
SMRiP32712.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati73 – 106TPR 1Add BLAST34
Repeati144 – 177TPR 2Add BLAST34

Sequence similaritiesi

Contains 2 TPR repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, TPR repeat

Phylogenomic databases

eggNOGiENOG4108W0S. Bacteria.
COG4235. LUCA.
HOGENOMiHOG000126931.
InParanoidiP32712.
KOiK04018.
OMAiVQARAMI.
PhylomeDBiP32712.

Family and domain databases

Gene3Di1.25.40.10. 2 hits.
InterProiIPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR019734. TPR_repeat.
[Graphical view]
SMARTiSM00028. TPR. 2 hits.
[Graphical view]
SUPFAMiSSF48452. SSF48452. 1 hit.
PROSITEiPS50005. TPR. 2 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P32712-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKQPKIPVKM LTTLTILMVF LCVGSYLLSP KWQAVRAEYQ RQRDPLHQFA
60 70 80 90 100
SQQTPEAQLQ ALQDKIRANP QNSEQWALLG EYYLWQNDYS NSLLAYRQAL
110 120 130 140 150
QLRGENAELY AALATVLYYQ ASQHMTAQTR AMIDKALALD SNEITALMLL
160 170 180 190
ASDAFMQANY AQAIELWQKV MDLNSPRVNR TQLVESINMA KLLQRRLD
Length:198
Mass (Da):22,784
Last modified:October 1, 1993 - v1
Checksum:i4F7E369ABC5949C3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X72298 Genomic DNA. Translation: CAA51047.1.
U00006 Genomic DNA. Translation: AAC43170.1.
U00096 Genomic DNA. Translation: AAD13459.1.
AP009048 Genomic DNA. Translation: BAE78078.1.
PIRiA57987.
RefSeqiNP_418500.1. NC_000913.3.
WP_000812896.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAD13459; AAD13459; b4076.
BAE78078; BAE78078; BAE78078.
GeneIDi948592.
KEGGiecj:JW4037.
eco:b4076.
PATRICi32123701. VBIEscCol129921_4199.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X72298 Genomic DNA. Translation: CAA51047.1.
U00006 Genomic DNA. Translation: AAC43170.1.
U00096 Genomic DNA. Translation: AAD13459.1.
AP009048 Genomic DNA. Translation: BAE78078.1.
PIRiA57987.
RefSeqiNP_418500.1. NC_000913.3.
WP_000812896.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP32712.
SMRiP32712.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261973. 10 interactors.
IntActiP32712. 5 interactors.
STRINGi511145.b4076.

Proteomic databases

PaxDbiP32712.
PRIDEiP32712.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD13459; AAD13459; b4076.
BAE78078; BAE78078; BAE78078.
GeneIDi948592.
KEGGiecj:JW4037.
eco:b4076.
PATRICi32123701. VBIEscCol129921_4199.

Organism-specific databases

EchoBASEiEB1893.
EcoGeneiEG11950. nrfG.

Phylogenomic databases

eggNOGiENOG4108W0S. Bacteria.
COG4235. LUCA.
HOGENOMiHOG000126931.
InParanoidiP32712.
KOiK04018.
OMAiVQARAMI.
PhylomeDBiP32712.

Enzyme and pathway databases

BioCyciEcoCyc:EG11950-MONOMER.
ECOL316407:JW4037-MONOMER.

Miscellaneous databases

PROiP32712.

Family and domain databases

Gene3Di1.25.40.10. 2 hits.
InterProiIPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR019734. TPR_repeat.
[Graphical view]
SMARTiSM00028. TPR. 2 hits.
[Graphical view]
SUPFAMiSSF48452. SSF48452. 1 hit.
PROSITEiPS50005. TPR. 2 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNRFG_ECOLI
AccessioniPrimary (citable) accession number: P32712
Secondary accession number(s): Q2M6M8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: November 2, 2016
This is version 122 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.