Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein NrfD

Gene

nrfD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Probably involved in the transfer of electrons from the quinone pool to the type-c cytochromes.

Enzyme and pathway databases

BioCyciEcoCyc:NRFD-MONOMER.
ECOL316407:JW4034-MONOMER.
MetaCyc:NRFD-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein NrfD
Gene namesi
Name:nrfD
Synonyms:yjcK
Ordered Locus Names:b4073, JW4034
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11947. nrfD.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei18 – 38HelicalSequence analysisAdd BLAST21
Transmembranei57 – 73HelicalSequence analysisAdd BLAST17
Transmembranei90 – 112HelicalSequence analysisAdd BLAST23
Transmembranei150 – 170HelicalSequence analysisAdd BLAST21
Transmembranei180 – 199HelicalSequence analysisAdd BLAST20
Transmembranei222 – 242HelicalSequence analysisAdd BLAST21
Transmembranei258 – 278HelicalSequence analysisAdd BLAST21
Transmembranei288 – 310HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001593221 – 318Protein NrfDAdd BLAST318

Proteomic databases

PaxDbiP32709.
PRIDEiP32709.

Interactioni

Protein-protein interaction databases

BioGridi4262676. 11 interactors.
STRINGi511145.b4073.

Structurei

3D structure databases

ProteinModelPortaliP32709.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NrfD family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105DVI. Bacteria.
COG3301. LUCA.
HOGENOMiHOG000278536.
InParanoidiP32709.
KOiK04015.
OMAiFVHRMET.

Family and domain databases

InterProiIPR017566. NrfD.
IPR005614. NrfD_fam.
[Graphical view]
PfamiPF03916. NrfD. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03148. cyt_nit_nrfD. 1 hit.

Sequencei

Sequence statusi: Complete.

P32709-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQTSAFHFE SLVWDWPIAI YLFLIGISAG LVTLAVLLRR FYPQAGGADS
60 70 80 90 100
TLLRTTLIVG PGAVILGLLI LVFHLTRPWT FWKLMFHYSF TSVMSMGVML
110 120 130 140 150
FQLYMVVLVL WLAKIFEHDL LALQQRWLPK LGIVQKVLSL LTPVHRGLET
160 170 180 190 200
LMLVLAVLLG AYTGFLLSAL KSYPFLNNPI LPVLFLFSGI SSGAAVALIA
210 220 230 240 250
MAIRQRSNPH STEAQFVHRM EIPVVWGEIF LLVAFFVGLA LGDDGKVRAL
260 270 280 290 300
VAALGGGFWT WWFWLGVAGL GLIVPMLLKP WVNRSSGIPA VLAACGASLV
310
GVLMLRFFIL YAGQLTVA
Length:318
Mass (Da):35,042
Last modified:August 29, 2003 - v2
Checksum:iB650FB208C4C4FEE
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti141L → V in CAA51044 (PubMed:8057835).Curated1
Sequence conflicti202A → R in CAA51044 (PubMed:8057835).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X72298 Genomic DNA. Translation: CAA51044.1.
U00006 Genomic DNA. Translation: AAC43167.1.
U00096 Genomic DNA. Translation: AAC77043.1.
AP009048 Genomic DNA. Translation: BAE78075.1.
PIRiH65215. D57987.
RefSeqiNP_418497.1. NC_000913.3.
WP_000195171.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC77043; AAC77043; b4073.
BAE78075; BAE78075; BAE78075.
GeneIDi948580.
KEGGiecj:JW4034.
eco:b4073.
PATRICi32123695. VBIEscCol129921_4196.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X72298 Genomic DNA. Translation: CAA51044.1.
U00006 Genomic DNA. Translation: AAC43167.1.
U00096 Genomic DNA. Translation: AAC77043.1.
AP009048 Genomic DNA. Translation: BAE78075.1.
PIRiH65215. D57987.
RefSeqiNP_418497.1. NC_000913.3.
WP_000195171.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP32709.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262676. 11 interactors.
STRINGi511145.b4073.

Proteomic databases

PaxDbiP32709.
PRIDEiP32709.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC77043; AAC77043; b4073.
BAE78075; BAE78075; BAE78075.
GeneIDi948580.
KEGGiecj:JW4034.
eco:b4073.
PATRICi32123695. VBIEscCol129921_4196.

Organism-specific databases

EchoBASEiEB1890.
EcoGeneiEG11947. nrfD.

Phylogenomic databases

eggNOGiENOG4105DVI. Bacteria.
COG3301. LUCA.
HOGENOMiHOG000278536.
InParanoidiP32709.
KOiK04015.
OMAiFVHRMET.

Enzyme and pathway databases

BioCyciEcoCyc:NRFD-MONOMER.
ECOL316407:JW4034-MONOMER.
MetaCyc:NRFD-MONOMER.

Miscellaneous databases

PROiP32709.

Family and domain databases

InterProiIPR017566. NrfD.
IPR005614. NrfD_fam.
[Graphical view]
PfamiPF03916. NrfD. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03148. cyt_nit_nrfD. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiNRFD_ECOLI
AccessioniPrimary (citable) accession number: P32709
Secondary accession number(s): Q2M6N1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: August 29, 2003
Last modified: November 2, 2016
This is version 119 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.