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Protein

Uncharacterized Na(+)/H(+) exchanger YjcE

Gene

yjcE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Antiport, Ion transport, Sodium transport, Transport

Keywords - Ligandi

Sodium

Enzyme and pathway databases

BioCyciEcoCyc:YJCE-MONOMER.
ECOL316407:JW4026-MONOMER.

Protein family/group databases

TCDBi2.A.36.3.1. the monovalent cation:proton antiporter-1 (cpa1) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized Na(+)/H(+) exchanger YjcE
Gene namesi
Name:yjcE
Ordered Locus Names:b4065, JW4026
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11940. yjcE.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei1 – 2121HelicalSequence analysisAdd
BLAST
Transmembranei28 – 4821HelicalSequence analysisAdd
BLAST
Transmembranei50 – 7021HelicalSequence analysisAdd
BLAST
Transmembranei85 – 10521HelicalSequence analysisAdd
BLAST
Transmembranei106 – 12621HelicalSequence analysisAdd
BLAST
Transmembranei165 – 18521HelicalSequence analysisAdd
BLAST
Transmembranei187 – 20721HelicalSequence analysisAdd
BLAST
Transmembranei222 – 24221HelicalSequence analysisAdd
BLAST
Transmembranei278 – 29821HelicalSequence analysisAdd
BLAST
Transmembranei310 – 33021HelicalSequence analysisAdd
BLAST
Transmembranei361 – 38121HelicalSequence analysisAdd
BLAST
Transmembranei398 – 41821HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 549549Uncharacterized Na(+)/H(+) exchanger YjcEPRO_0000052399Add
BLAST

Proteomic databases

PaxDbiP32703.

Interactioni

Protein-protein interaction databases

BioGridi4262673. 239 interactions.
STRINGi511145.b4065.

Structurei

3D structure databases

ProteinModelPortaliP32703.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105EEQ. Bacteria.
COG0025. LUCA.
HOGENOMiHOG000263347.
InParanoidiP32703.
KOiK03316.
OMAiHRQHLVG.
PhylomeDBiP32703.

Family and domain databases

InterProiIPR006153. Cation/H_exchanger.
IPR018422. Cation/H_exchanger_CPA1.
IPR004705. Cation/H_exchanger_CPA1_bac.
[Graphical view]
PANTHERiPTHR10110. PTHR10110. 1 hit.
PfamiPF00999. Na_H_Exchanger. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00831. a_cpa1. 1 hit.

Sequencei

Sequence statusi: Complete.

P32703-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEIFFTILIM TLVVSLSGVV TRVMPFQIPL PLMQIAIGAL LAWPTFGLHV
60 70 80 90 100
EFDPELFLVL FIPPLLFADG WKTPTREFLE HGREIFGLAL ALVVVTVVGI
110 120 130 140 150
GFLIYWVVPG IPLIPAFALA AVLSPTDAVA LSGIVGEGRI PKKIMGILQG
160 170 180 190 200
EALMNDASGL VSLKFAVAVA MGTMIFTVGG ATVEFMKVAI GGILAGFVVS
210 220 230 240 250
WLYGRSLRFL SRWGGDEPAT QIVLLFLLPF ASYLIAEHIG VSGILAAVAA
260 270 280 290 300
GMTITRSGVM RRAPLAMRLR ANSTWAMLEF VFNGMVFLLL GLQLPGILET
310 320 330 340 350
SLMAAEIDPN VEIWMLFTNI ILIYAALMLV RFGWLWTMKK FSNRFLKKKP
360 370 380 390 400
MEFGSWTTRE ILIASFAGVR GAITLAGVLS IPLLLPDGNV FPARYELVFL
410 420 430 440 450
AAGVILFSLF VGVVMLPILL QHIEVADHSQ QLKEERIARA ATAEVAIVAI
460 470 480 490 500
QKMEERLAAD TEENIDNQLL TEVSSRVIGN LRRRADGRND VESSVQEENL
510 520 530 540
ERRFRLAALR SERAELYHLR ATREISNETL QKLLHDLDLL EALLIEENQ
Length:549
Mass (Da):60,523
Last modified:October 1, 1993 - v1
Checksum:i6F317CF098117DC3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00006 Genomic DNA. Translation: AAC43159.1.
U00096 Genomic DNA. Translation: AAC77035.1.
AP009048 Genomic DNA. Translation: BAE78067.1.
PIRiH65214.
RefSeqiNP_418489.1. NC_000913.3.
WP_000402210.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC77035; AAC77035; b4065.
BAE78067; BAE78067; BAE78067.
GeneIDi948577.
KEGGiecj:JW4026.
eco:b4065.
PATRICi32123677. VBIEscCol129921_4187.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00006 Genomic DNA. Translation: AAC43159.1.
U00096 Genomic DNA. Translation: AAC77035.1.
AP009048 Genomic DNA. Translation: BAE78067.1.
PIRiH65214.
RefSeqiNP_418489.1. NC_000913.3.
WP_000402210.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP32703.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262673. 239 interactions.
STRINGi511145.b4065.

Protein family/group databases

TCDBi2.A.36.3.1. the monovalent cation:proton antiporter-1 (cpa1) family.

Proteomic databases

PaxDbiP32703.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC77035; AAC77035; b4065.
BAE78067; BAE78067; BAE78067.
GeneIDi948577.
KEGGiecj:JW4026.
eco:b4065.
PATRICi32123677. VBIEscCol129921_4187.

Organism-specific databases

EchoBASEiEB1884.
EcoGeneiEG11940. yjcE.

Phylogenomic databases

eggNOGiENOG4105EEQ. Bacteria.
COG0025. LUCA.
HOGENOMiHOG000263347.
InParanoidiP32703.
KOiK03316.
OMAiHRQHLVG.
PhylomeDBiP32703.

Enzyme and pathway databases

BioCyciEcoCyc:YJCE-MONOMER.
ECOL316407:JW4026-MONOMER.

Miscellaneous databases

PROiP32703.

Family and domain databases

InterProiIPR006153. Cation/H_exchanger.
IPR018422. Cation/H_exchanger_CPA1.
IPR004705. Cation/H_exchanger_CPA1_bac.
[Graphical view]
PANTHERiPTHR10110. PTHR10110. 1 hit.
PfamiPF00999. Na_H_Exchanger. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00831. a_cpa1. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYJCE_ECOLI
AccessioniPrimary (citable) accession number: P32703
Secondary accession number(s): Q2M6N9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: September 7, 2016
This is version 121 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.