P32633 (MTC7_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative maintenance of telomere capping protein 7

Gene names

Name:	MTC7
Ordered Locus Names:	YEL033W
ORF Names:	SYGP-ORF22

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	139 AA.
Sequence status	Complete.
Protein existence	Uncertain

General annotation (Comments)

Function	May be involved in telomere capping. Ref.3
Subcellular location	Membrane; Multi-pass membrane protein Potential.
Caution	Product of a dubious gene prediction.

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 139	139	Putative maintenance of telomere capping protein 7		PRO_0000202608
Regions
	Transmembrane	13 – 33	21	Helical; Potential
	Transmembrane	42 – 62	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	P32633 [UniParc]. Last modified October 1, 1993. Version 1. Checksum: 301A1E922A71D79A	FASTA	139	16,094
	10 20 30 40 50 60 MKKEKKTPTP LPSHHVLFAE PGFFLCNFFF VLLKHTQINP FFYFLFILLF IIYIAIIYFV 70 80 90 100 110 120 FIRISHFSFS LCRQCNSLGR MIFMCAYLPA ASSRSVANPA LPPQKKKKKK KKGTLRTGEV 130 EEQAKGNISF DLCGKQNFQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome V." Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E., Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., Hunicke-Smith S., Hyman R.W. , Kayser A., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Norgren R., Oefner P., Oh C., Petel F.X., Roberts D., Sehl P., Schramm S., Shogren T., Smith V., Taylor P., Wei Y., Botstein D., Davis R.W. Nature 387:78-81(1997) [PubMed: 9169868] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"A genomewide suppressor and enhancer analysis of cdc13-1 reveals varied cellular processes influencing telomere capping in Saccharomyces cerevisiae." Addinall S.G., Downey M., Yu M., Zubko M.K., Dewar J., Leake A., Hallinan J., Shaw O., James K., Wilkinson D.J., Wipat A., Durocher D., Lydall D. Genetics 180:2251-2266(2008) [PubMed: 18845848] [Abstract] Cited for: FUNCTION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U18779 Genomic DNA. Translation: AAB65009.1. BK006939 Genomic DNA. Translation: DAA07620.1.
PIR	S30850.
RefSeq	NP_010881.1. NM_001178848.1.
3D structure databases
ProteinModelPortal	P32633.
ModBase	Search...
Protein-protein interaction databases
IntAct	P32633. 1 interaction.
STRING	P32633.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YEL033W; YEL033W; YEL033W.
GeneID	856678.
KEGG	sce:YEL033W.
Organism-specific databases
SGD	S000000759. MTC7.
Gene expression databases
ArrayExpress	P32633.
Genevestigator	P32633.
GermOnline	YEL033W. Saccharomyces cerevisiae.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

MTC7_YEAST

Accession

Primary (citable) accession number: P32633
Secondary accession number(s): D3DLL6

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1993
Last sequence update:	October 1, 1993
Last modified:	September 21, 2011
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program