Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P32616

- YEF5_YEAST

UniProt

P32616 - YEF5_YEAST

Protein

Uncharacterized protein YEL045C

Gene

YEL045C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 70 (01 Oct 2014)
      Sequence version 1 (01 Oct 1993)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Required for optimal growth under alkaline conditions.

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi15 – 228ATPSequence Analysis

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized protein YEL045C
    Gene namesi
    Ordered Locus Names:YEL045C
    ORF Names:SYGP-ORF33
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome V

    Organism-specific databases

    CYGDiYEL045c.
    SGDiS000000771. YEL045C.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    Pathology & Biotechi

    Disruption phenotypei

    Growth defect under alkaline conditions and citric acid stress.3 Publications

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 141141Uncharacterized protein YEL045CPRO_0000202606Add
    BLAST

    Expressioni

    Inductioni

    Repressed after alkaline pH stress.1 Publication

    Gene expression databases

    GenevestigatoriP32616.

    Interactioni

    Protein-protein interaction databases

    STRINGi4932.YEL045C.

    Structurei

    3D structure databases

    ProteinModelPortaliP32616.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei38 – 5821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei67 – 8721HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    OrthoDBiEOG741ZF0.

    Sequencei

    Sequence statusi: Complete.

    P32616-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKCHAKRTLA FLATALPLSG KSRACTRTPQ SFASGFRAAA PFLFSRCFAL    50
    CITHCALFHL PYSFTGFSFY FFVFFRLFLH WIYAFCICNS TYVYIYKQVL 100
    SLPVKSSMCP SRLSCSVWYR VILTYIYVHC FRWLVRNHLL S 141
    Length:141
    Mass (Da):16,469
    Last modified:October 1, 1993 - v1
    Checksum:iF6604AC5343A5D5C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U18779 Genomic DNA. Translation: AAB64997.1.
    AY558443 Genomic DNA. Translation: AAS56769.1.
    BK006939 Genomic DNA. No translation available.
    PIRiS30832.

    Genome annotation databases

    EnsemblFungiiYEL045C; YEL045C; YEL045C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U18779 Genomic DNA. Translation: AAB64997.1 .
    AY558443 Genomic DNA. Translation: AAS56769.1 .
    BK006939 Genomic DNA. No translation available.
    PIRi S30832.

    3D structure databases

    ProteinModelPortali P32616.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 4932.YEL045C.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YEL045C ; YEL045C ; YEL045C .

    Organism-specific databases

    CYGDi YEL045c.
    SGDi S000000771. YEL045C.

    Phylogenomic databases

    OrthoDBi EOG741ZF0.

    Gene expression databases

    Genevestigatori P32616.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. "The transcriptional response to alkaline pH in Saccharomyces cerevisiae: evidence for calcium-mediated signalling."
      Serrano R., Ruiz A., Bernal D., Chambers J.R., Arino J.
      Mol. Microbiol. 46:1319-1333(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: INDUCTION.
    5. "Copper and iron are the limiting factors for growth of the yeast Saccharomyces cerevisiae in an alkaline environment."
      Serrano R., Bernal D., Simon E., Arino J.
      J. Biol. Chem. 279:19698-19704(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: DISRUPTION PHENOTYPE.
    6. "Evidence of a new role for the high-osmolarity glycerol mitogen-activated protein kinase pathway in yeast: regulating adaptation to citric acid stress."
      Lawrence C.L., Botting C.H., Antrobus R., Coote P.J.
      Mol. Cell. Biol. 24:3307-3323(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: DISRUPTION PHENOTYPE.
    7. "A genomic screen for yeast vacuolar membrane ATPase mutants."
      Sambade M., Alba M., Smardon A.M., West R.W., Kane P.M.
      Genetics 170:1539-1551(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: DISRUPTION PHENOTYPE.

    Entry informationi

    Entry nameiYEF5_YEAST
    AccessioniPrimary (citable) accession number: P32616
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1993
    Last sequence update: October 1, 1993
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    2. Yeast chromosome V
      Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names

    External Data

    Dasty 3