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Protein

TRAPP-associated protein TCA17

Gene

TCA17

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Required, together with the TRAPP II subunit TRS33, for TRAPP II complex assembly or stability, and for proper Golgi localization of TRAPP and the Rab GTPase YPT31.2 Publications

Miscellaneous

Present with 8660 molecules/cell in log phase SD medium.1 Publication

GO - Biological processi

  • cellular protein-containing complex assembly Source: SGD
  • early endosome to Golgi transport Source: SGD
  • ER to Golgi vesicle-mediated transport Source: InterPro

Enzyme and pathway databases

BioCyciYEAST:G3O-30166-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
TRAPP-associated protein TCA17
Alternative name(s):
17 kDa TRAPP complex-associated protein
Gene namesi
Name:TCA17
Ordered Locus Names:YEL048C
ORF Names:SYGP-ORF36
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome V

Organism-specific databases

EuPathDBiFungiDB:YEL048C
SGDiS000000774 TCA17

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Golgi apparatus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002026051 – 152TRAPP-associated protein TCA17Add BLAST152

Proteomic databases

MaxQBiP32613
PaxDbiP32613
PRIDEiP32613

Interactioni

Subunit structurei

Interacts with the TRAPP II complex; TRAPP II subunits TRS33 and TRS65 are required for this interaction.2 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
TRS130Q036607EBI-22370,EBI-19461

Protein-protein interaction databases

BioGridi36682, 75 interactors
DIPiDIP-5288N
IntActiP32613, 14 interactors
STRINGi4932.YEL048C

Structurei

Secondary structure

1152
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi6 – 11Combined sources6
Beta strandi17 – 21Combined sources5
Helixi33 – 48Combined sources16
Beta strandi57 – 60Combined sources4
Beta strandi64 – 69Combined sources6
Beta strandi72 – 78Combined sources7
Turni80 – 82Combined sources3
Beta strandi85 – 91Combined sources7
Helixi92 – 94Combined sources3
Helixi99 – 120Combined sources22
Helixi125 – 127Combined sources3
Helixi130 – 145Combined sources16
Helixi149 – 152Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3PR6X-ray1.80A1-152[»]
ProteinModelPortaliP32613
SMRiP32613
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000000836
InParanoidiP32613
KOiK20312
OMAiRTEMEHI
OrthoDBiEOG092C4WNQ

Family and domain databases

InterProiView protein in InterPro
IPR011012 Longin-like_dom_sf
IPR006722 Sedlin
PfamiView protein in Pfam
PF04628 Sedlin_N, 1 hit
SUPFAMiSSF64356 SSF64356, 1 hit

Sequencei

Sequence statusi: Complete.

P32613-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLRPCFVSL IDESDKPILI YVPNEAENEM NDVLKYNVLS NISLDYFESA
60 70 80 90 100
LVEWHSLDSK PLLKSIFQLE GVSVFAMLIK QTGLKIVIGF EQKSLSGADD
110 120 130 140 150
EFEAINQIFE TVRKIYIRVK CNPLLVSGDE KSIIKSLERK FDELFISTEV

EL
Length:152
Mass (Da):17,354
Last modified:October 1, 1993 - v1
Checksum:iF7AF8E6EC34F193D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti2S → T in AAS56768 (PubMed:17322287).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18779 Genomic DNA Translation: AAB64994.1
AY558442 Genomic DNA Translation: AAS56768.1
BK006939 Genomic DNA Translation: DAA07606.1
PIRiS30829
RefSeqiNP_010866.1, NM_001178863.1

Genome annotation databases

EnsemblFungiiYEL048C; YEL048C; YEL048C
GeneIDi856663
KEGGisce:YEL048C

Similar proteinsi

Entry informationi

Entry nameiTCA17_YEAST
AccessioniPrimary (citable) accession number: P32613
Secondary accession number(s): D3DLK2, Q6Q561
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: May 23, 2018
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

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