P32612 (PAU2_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Seripauperin-2

Gene names

Name:	PAU2
Ordered Locus Names:	YEL049W
ORF Names:	SYGP-ORF12

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	120 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Membrane; Single-pass membrane protein Potential.
Sequence similarities	Belongs to the SRP1/TIP1 family. Seripauperin subfamily.

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	response to stress Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
YHR080C	P38800	1	EBI-12930,EBI-24597

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 120	120	Seripauperin-2		PRO_0000203779
Regions
	Transmembrane	7 – 24	18	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	P32612 [UniParc]. Last modified October 1, 1993. Version 1. Checksum: 48C39A82357497C7	FASTA	120	12,820
	10 20 30 40 50 60 MVKLTSIAAG VAAIAATASA TTTLAQSDER VNLVELGVYV SDIRAHLAQY YSFQAAHPTE 70 80 90 100 110 120 TYPIEVAEAV FNYGDFTTML TGIAPDQVTR MITGVPWYSS RLKPAISSAL SKDGIYTIAN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome V." Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E., Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., Hunicke-Smith S., Hyman R.W. , Kayser A., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Norgren R., Oefner P., Oh C., Petel F.X., Roberts D., Sehl P., Schramm S., Shogren T., Smith V., Taylor P., Wei Y., Botstein D., Davis R.W. Nature 387:78-81(1997) [PubMed: 9169868] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"Seripauperins of Saccharomyces cerevisiae: a new multigene family encoding serine-poor relatives of serine-rich proteins." Viswanathan M., Muthukumar G., Cong Y.-S., Lenard J. Gene 148:149-153(1994) [PubMed: 7926827] [Abstract] Cited for: GENE NAME.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U18779 Genomic DNA. Translation: AAB64993.1. BK006939 Genomic DNA. Translation: DAA07605.1.
PIR	S30828.
RefSeq	NP_010865.1. NM_001178864.1.
3D structure databases
ProteinModelPortal	P32612.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-4138N.
IntAct	P32612. 1 interaction.
MINT	MINT-513025.
STRING	P32612.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YEL049W; YEL049W; YEL049W.
GeneID	856662.
KEGG	sce:YEL049W.
Organism-specific databases
CYGD	YEL049w.
SGD	S000000775. PAU2.
Phylogenomic databases
GeneTree	EFGT00050000002934.
HOGENOM	HBG204450.
OrthoDB	EOG4WT0MF.
Gene expression databases
ArrayExpress	P32612.
Genevestigator	P32612.
GermOnline	YEL049W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR000992. SRP1_TIP1. [Graphical view]
Pfam	PF00660. SRP1_TIP1. 1 hit. [Graphical view]
PROSITE	PS00724. SRP1_TIP1. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	982660.

Entry information

Entry name

PAU2_YEAST

Accession

Primary (citable) accession number: P32612
Secondary accession number(s): D3DLK1

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1993
Last sequence update:	October 1, 1993
Last modified:	December 14, 2011
This is version 77 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program