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P32593 (MOS_MSVMT) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Serine/threonine-protein kinase-transforming protein mos

EC=2.7.11.1
Gene names
Name:V-MOS
OrganismMoloney murine sarcoma virus (strain ts110) (MoMSV)
Taxonomic identifier31691 [NCBI]
Taxonomic lineageVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeGammaretrovirus
Virus hostMus musculus (Mouse) [TaxID: 10090]

Protein attributes

Sequence length354 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Miscellaneous

This protein is probably translated as a Gag-Mos polyprotein.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 354354Serine/threonine-protein kinase-transforming protein mos
PRO_0000086362

Regions

Domain74 – 350277Protein kinase
Nucleotide binding80 – 889ATP By similarity

Sites

Active site2091Proton acceptor By similarity
Binding site1011ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
P32593 [UniParc].

Last modified October 1, 1993. Version 1.
Checksum: 95F845823B748965

FASTA35438,851
        10         20         30         40         50         60 
VSHVTVPSEG VMPSPLSLCR YLPRELSPSV DSRSCSIPLV APRKAGKLFL GTTPPRAPGL 

        70         80         90        100        110        120 
PRRLAWFSID WEQVCLMHRL GSGGFGSVYK ATYHGVPVAI KQVNKCTEDL RASQRSFWAE 

       130        140        150        160        170        180 
LNIAGLRHDN IVRVVAASTR TPEDSNSLGT IIMEFGGNVT LHQVIYDATR SPEPLSCRKQ 

       190        200        210        220        230        240 
LSLGKCLKYS LDVVNGLLFL HSQSILHLDL KPANILISEQ DVCKISDFGC SQKLQVLRGR 

       250        260        270        280        290        300 
QASPPHIGGT YTHQAPEILK GEIATPKADI YSFGITLWQM TTREVPYSGE PQYVQYAVVA 

       310        320        330        340        350 
YNLRPSLAGA VFTASLTGKA LQNIIQSCWE ARGLQRPSAE LLQRDLKAFR GTLG 

« Hide

References

[1]"Moloney murine sarcoma virus MuSVts110 DNA: cloning, nucleotide sequence, and gene expression."
Huai L., Chiocca S.M., Gilbreth M.A., Ainsworth J.R., Bishop L.A., Murphy E.C. Jr.
J. Virol. 66:5329-5337(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M96854 Genomic DNA. No translation available.
PIRTVMVMU. B42745.

3D structure databases

ProteinModelPortalP32593.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

BRENDA2.7.10.2. 3394.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMOS_MSVMT
AccessionPrimary (citable) accession number: P32593
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: October 16, 2013
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families