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Protein

Heat shock protein homolog SSE2

Gene

SSE2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Has a calcium-dependent calmodulin-binding activity.

Miscellaneous

Present with 6300 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • adenyl-nucleotide exchange factor activity Source: SGD
  • ATP binding Source: UniProtKB-KW
  • calmodulin binding Source: UniProtKB-KW

GO - Biological processi

  • protein folding Source: SGD
  • protein refolding Source: SGD

Keywordsi

Molecular functionCalmodulin-binding
Biological processStress response
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-29117-MONOMER
ReactomeiR-SCE-3371453 Regulation of HSF1-mediated heat shock response

Names & Taxonomyi

Protein namesi
Recommended name:
Heat shock protein homolog SSE2
Gene namesi
Name:SSE2
Synonyms:HSP
Ordered Locus Names:YBR169C
ORF Names:YBR1221
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:YBR169C
SGDiS000000373 SSE2

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000783971 – 693Heat shock protein homolog SSE2Add BLAST693

Proteomic databases

MaxQBiP32590
PaxDbiP32590
PRIDEiP32590

2D gel databases

UCD-2DPAGEP32590

PTM databases

iPTMnetiP32590

Expressioni

Inductioni

By upshift to 37 degrees Celsius.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi32869, 94 interactors
DIPiDIP-4862N
IntActiP32590, 19 interactors
MINTiP32590
STRINGi4932.YBR169C

Structurei

3D structure databases

ProteinModelPortaliP32590
SMRiP32590
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.Curated

Phylogenomic databases

GeneTreeiENSGT00390000016919
HOGENOMiHOG000228138
InParanoidiP32590
KOiK09485
OMAiKMDQPPQ
OrthoDBiEOG092C17NN

Family and domain databases

Gene3Di1.20.1270.10, 1 hit
2.60.34.10, 1 hit
InterProiView protein in InterPro
IPR018181 Heat_shock_70_CS
IPR029048 HSP70_C_sf
IPR029047 HSP70_peptide-bd_sf
IPR013126 Hsp_70_fam
PANTHERiPTHR19375 PTHR19375, 1 hit
PfamiView protein in Pfam
PF00012 HSP70, 1 hit
PRINTSiPR00301 HEATSHOCK70
SUPFAMiSSF100920 SSF100920, 2 hits
SSF100934 SSF100934, 1 hit
PROSITEiView protein in PROSITE
PS00329 HSP70_2, 1 hit
PS01036 HSP70_3, 1 hit

Sequencei

Sequence statusi: Complete.

P32590-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTPFGLDLG NNNSVLAVAR NRGIDVVVNE VSNRSTPSLV GFGPRNRYLG
60 70 80 90 100
ESGKTKQTSN VKNTVENLKR IIGLKFKDPE FDIENKFFTS KLVQLKNGKV
110 120 130 140 150
GVEVEFGGKT HVFSATQLTA MFIDKVKHTV QEETKSSITD VCLAVPVWYS
160 170 180 190 200
EEQRYNIADA ARIAGLNPVR IVNDVTAAAV SYGVFKNDLP GPEEKPRIIG
210 220 230 240 250
LVDIGHSTYT CSIMAFRKGE MKVLGTAYDK HFGGRDFDRA ITEHFADQFK
260 270 280 290 300
DKYKIDIRKN PKAYNRILIA AEKLKKVLSA NTTAPFSVES VMDDIDVSSQ
310 320 330 340 350
LSREELEELV EPLLKRVTYP ITNALAQAKL TVNDIDFVEI IGGTTRIPVL
360 370 380 390 400
KKSISDVFGK PLSSTLNQDE AVAKGAAFIC AIHSPTLRVR PFKFEDIDPY
410 420 430 440 450
SVSYTWDKQV DDEDRLEVFP ANSSYPSTKL ITLHRTGDFS MKAVYTHPSK
460 470 480 490 500
LPKGTSTTIA KWSFTGVKVP KDQDFIPVKV KLRCDPSGLH IIENAYTTED
510 520 530 540 550
ITVQEPVPLP EDAPEDAEPQ FKEVTKTIKK DVLGMTAKTF ALNPVELNDL
560 570 580 590 600
IEKENELRNQ DKLVAETEDR KNALEEYIYT LRAKLDDEYS DFASDAEKEK
610 620 630 640 650
LKNMLATTEN WLYGDGDDST KAKYIAKYEE LASLGNIIRG RYLAKEEEKR
660 670 680 690
QALRANQETS KMNDIAEKLA EQRRARAASD DSDDNNDENM DLD
Length:693
Mass (Da):77,621
Last modified:January 23, 2007 - v3
Checksum:iD6BC9656D93895C2
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti160 – 167Missing in CAA51027 (PubMed:8257794).Curated8

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D38369 mRNA Translation: BAA07450.1
D38371 Genomic DNA Translation: BAA07452.1
X72224 Genomic DNA Translation: CAA51027.1
Z36038 Genomic DNA Translation: CAA85130.1
AY692880 Genomic DNA Translation: AAT92899.1
BK006936 Genomic DNA Translation: DAA07285.1
PIRiJN0843
RefSeqiNP_009728.1, NM_001178517.1

Genome annotation databases

EnsemblFungiiYBR169C; YBR169C; YBR169C
GeneIDi852467
KEGGisce:YBR169C

Similar proteinsi

Entry informationi

Entry nameiHSP79_YEAST
AccessioniPrimary (citable) accession number: P32590
Secondary accession number(s): D6VQG5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 156 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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