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P32564 (SCM4_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 92. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein SCM4
Alternative name(s):
Suppressor of CDC4 mutation 4
Gene names
Name:SCM4
Ordered Locus Names:YGR049W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length187 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Miscellaneous

Present with 3210 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the ATG33 family.

Ontologies

Keywords
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 187187Protein SCM4
PRO_0000097626

Regions

Transmembrane11 – 3121Helical; Potential
Transmembrane45 – 6521Helical; Potential
Transmembrane80 – 10021Helical; Potential
Transmembrane162 – 18221Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P32564 [UniParc].

Last modified October 1, 1993. Version 1.
Checksum: 6DE7C5C791B13568

FASTA18720,118
        10         20         30         40         50         60 
MQVSPAIVKG IAVSSLGLYA GILTSSTVIS ITTPINVLTQ HLKNVLCTLG CWSTVLGGLA 

        70         80         90        100        110        120 
TGAFGLSYYL AAPGERPNYL LCGLGVAPLS AAYLYLVSLF NHKLAPKCTR DQNDLEKQKD 

       130        140        150        160        170        180 
EKLPQHHPEV KDGEAACPFS KMNNAKTLKP ESERSVKCHS YMSLHMSIVT GITIFTFGKC 


ILDGFKA 

« Hide

References

« Hide 'large scale' references
[1]"SCM4, a gene that suppresses mutant cdc4 function in budding yeast."
Smith S.A., Kumar P., Johnston I., Rosamond J.
Mol. Gen. Genet. 235:285-291(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Quantitative trait loci mapped to single-nucleotide resolution in yeast."
Deutschbauer A.M., Davis R.W.
Nat. Genet. 37:1333-1340(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: SK1.
[3]"The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E. expand/collapse author list , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[4]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[5]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X69566 Genomic DNA. Translation: CAA49291.1.
DQ115391 Genomic DNA. Translation: AAZ22464.1.
Z72834 Genomic DNA. Translation: CAA97049.1.
BK006941 Genomic DNA. Translation: DAA08147.1.
PIRS30093.
RefSeqNP_011563.1. NM_001181178.1.

3D structure databases

ProteinModelPortalP32564.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid33296. 6 interactions.
DIPDIP-1870N.
IntActP32564. 2 interactions.
MINTMINT-408265.
STRING4932.YGR049W.

Proteomic databases

MaxQBP32564.
PaxDbP32564.
PeptideAtlasP32564.

Protocols and materials databases

DNASU852940.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYGR049W; YGR049W; YGR049W.
GeneID852940.
KEGGsce:YGR049W.

Organism-specific databases

CYGDYGR049w.
SGDS000003281. SCM4.

Phylogenomic databases

eggNOGNOG68417.
GeneTreeENSGT00530000067118.
HOGENOMHOG000000951.
OMATGITIFT.
OrthoDBEOG7G7M1D.

Enzyme and pathway databases

BioCycYEAST:G3O-30767-MONOMER.

Gene expression databases

GenevestigatorP32564.

Family and domain databases

ProtoNetSearch...

Other

NextBio972681.

Entry information

Entry nameSCM4_YEAST
AccessionPrimary (citable) accession number: P32564
Secondary accession number(s): D6VUI6, Q45U35
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: May 14, 2014
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome VII

Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families