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P32564

- SCM4_YEAST

UniProt

P32564 - SCM4_YEAST

Protein

Protein SCM4

Gene

SCM4

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 93 (01 Oct 2014)
      Sequence version 1 (01 Oct 1993)
      Previous versions | rss
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    Functioni

    Enzyme and pathway databases

    BioCyciYEAST:G3O-30767-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein SCM4
    Alternative name(s):
    Suppressor of CDC4 mutation 4
    Gene namesi
    Name:SCM4
    Ordered Locus Names:YGR049W
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome VII

    Organism-specific databases

    CYGDiYGR049w.
    SGDiS000003281. SCM4.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 187187Protein SCM4PRO_0000097626Add
    BLAST

    Proteomic databases

    MaxQBiP32564.
    PaxDbiP32564.
    PeptideAtlasiP32564.

    Expressioni

    Gene expression databases

    GenevestigatoriP32564.

    Interactioni

    Protein-protein interaction databases

    BioGridi33296. 6 interactions.
    DIPiDIP-1870N.
    IntActiP32564. 2 interactions.
    MINTiMINT-408265.
    STRINGi4932.YGR049W.

    Structurei

    3D structure databases

    ProteinModelPortaliP32564.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei11 – 3121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei45 – 6521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei80 – 10021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei162 – 18221HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATG33 family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG68417.
    GeneTreeiENSGT00530000067118.
    HOGENOMiHOG000000951.
    OMAiTGITIFT.
    OrthoDBiEOG7G7M1D.

    Sequencei

    Sequence statusi: Complete.

    P32564-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQVSPAIVKG IAVSSLGLYA GILTSSTVIS ITTPINVLTQ HLKNVLCTLG    50
    CWSTVLGGLA TGAFGLSYYL AAPGERPNYL LCGLGVAPLS AAYLYLVSLF 100
    NHKLAPKCTR DQNDLEKQKD EKLPQHHPEV KDGEAACPFS KMNNAKTLKP 150
    ESERSVKCHS YMSLHMSIVT GITIFTFGKC ILDGFKA 187
    Length:187
    Mass (Da):20,118
    Last modified:October 1, 1993 - v1
    Checksum:i6DE7C5C791B13568
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X69566 Genomic DNA. Translation: CAA49291.1.
    DQ115391 Genomic DNA. Translation: AAZ22464.1.
    Z72834 Genomic DNA. Translation: CAA97049.1.
    BK006941 Genomic DNA. Translation: DAA08147.1.
    PIRiS30093.
    RefSeqiNP_011563.1. NM_001181178.1.

    Genome annotation databases

    EnsemblFungiiYGR049W; YGR049W; YGR049W.
    GeneIDi852940.
    KEGGisce:YGR049W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X69566 Genomic DNA. Translation: CAA49291.1 .
    DQ115391 Genomic DNA. Translation: AAZ22464.1 .
    Z72834 Genomic DNA. Translation: CAA97049.1 .
    BK006941 Genomic DNA. Translation: DAA08147.1 .
    PIRi S30093.
    RefSeqi NP_011563.1. NM_001181178.1.

    3D structure databases

    ProteinModelPortali P32564.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 33296. 6 interactions.
    DIPi DIP-1870N.
    IntActi P32564. 2 interactions.
    MINTi MINT-408265.
    STRINGi 4932.YGR049W.

    Proteomic databases

    MaxQBi P32564.
    PaxDbi P32564.
    PeptideAtlasi P32564.

    Protocols and materials databases

    DNASUi 852940.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YGR049W ; YGR049W ; YGR049W .
    GeneIDi 852940.
    KEGGi sce:YGR049W.

    Organism-specific databases

    CYGDi YGR049w.
    SGDi S000003281. SCM4.

    Phylogenomic databases

    eggNOGi NOG68417.
    GeneTreei ENSGT00530000067118.
    HOGENOMi HOG000000951.
    OMAi TGITIFT.
    OrthoDBi EOG7G7M1D.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-30767-MONOMER.

    Miscellaneous databases

    NextBioi 972681.

    Gene expression databases

    Genevestigatori P32564.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "SCM4, a gene that suppresses mutant cdc4 function in budding yeast."
      Smith S.A., Kumar P., Johnston I., Rosamond J.
      Mol. Gen. Genet. 235:285-291(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "Quantitative trait loci mapped to single-nucleotide resolution in yeast."
      Deutschbauer A.M., Davis R.W.
      Nat. Genet. 37:1333-1340(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: SK1.
    3. "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
      Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E.
      , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
      Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiSCM4_YEAST
    AccessioniPrimary (citable) accession number: P32564
    Secondary accession number(s): D6VUI6, Q45U35
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1993
    Last sequence update: October 1, 1993
    Last modified: October 1, 2014
    This is version 93 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 3210 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome VII
      Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

    External Data

    Dasty 3