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P32564

- SCM4_YEAST

UniProt

P32564 - SCM4_YEAST

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Protein

Protein SCM4

Gene
SCM4, YGR049W
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciYEAST:G3O-30767-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein SCM4
Alternative name(s):
Suppressor of CDC4 mutation 4
Gene namesi
Name:SCM4
Ordered Locus Names:YGR049W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome VII

Organism-specific databases

CYGDiYGR049w.
SGDiS000003281. SCM4.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei11 – 3121Helical; Reviewed predictionAdd
BLAST
Transmembranei45 – 6521Helical; Reviewed predictionAdd
BLAST
Transmembranei80 – 10021Helical; Reviewed predictionAdd
BLAST
Transmembranei162 – 18221Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 187187Protein SCM4PRO_0000097626Add
BLAST

Proteomic databases

MaxQBiP32564.
PaxDbiP32564.
PeptideAtlasiP32564.

Expressioni

Gene expression databases

GenevestigatoriP32564.

Interactioni

Protein-protein interaction databases

BioGridi33296. 6 interactions.
DIPiDIP-1870N.
IntActiP32564. 2 interactions.
MINTiMINT-408265.
STRINGi4932.YGR049W.

Structurei

3D structure databases

ProteinModelPortaliP32564.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATG33 family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG68417.
GeneTreeiENSGT00530000067118.
HOGENOMiHOG000000951.
OMAiTGITIFT.
OrthoDBiEOG7G7M1D.

Sequencei

Sequence statusi: Complete.

P32564-1 [UniParc]FASTAAdd to Basket

« Hide

MQVSPAIVKG IAVSSLGLYA GILTSSTVIS ITTPINVLTQ HLKNVLCTLG    50
CWSTVLGGLA TGAFGLSYYL AAPGERPNYL LCGLGVAPLS AAYLYLVSLF 100
NHKLAPKCTR DQNDLEKQKD EKLPQHHPEV KDGEAACPFS KMNNAKTLKP 150
ESERSVKCHS YMSLHMSIVT GITIFTFGKC ILDGFKA 187
Length:187
Mass (Da):20,118
Last modified:October 1, 1993 - v1
Checksum:i6DE7C5C791B13568
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X69566 Genomic DNA. Translation: CAA49291.1.
DQ115391 Genomic DNA. Translation: AAZ22464.1.
Z72834 Genomic DNA. Translation: CAA97049.1.
BK006941 Genomic DNA. Translation: DAA08147.1.
PIRiS30093.
RefSeqiNP_011563.1. NM_001181178.1.

Genome annotation databases

EnsemblFungiiYGR049W; YGR049W; YGR049W.
GeneIDi852940.
KEGGisce:YGR049W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X69566 Genomic DNA. Translation: CAA49291.1 .
DQ115391 Genomic DNA. Translation: AAZ22464.1 .
Z72834 Genomic DNA. Translation: CAA97049.1 .
BK006941 Genomic DNA. Translation: DAA08147.1 .
PIRi S30093.
RefSeqi NP_011563.1. NM_001181178.1.

3D structure databases

ProteinModelPortali P32564.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 33296. 6 interactions.
DIPi DIP-1870N.
IntActi P32564. 2 interactions.
MINTi MINT-408265.
STRINGi 4932.YGR049W.

Proteomic databases

MaxQBi P32564.
PaxDbi P32564.
PeptideAtlasi P32564.

Protocols and materials databases

DNASUi 852940.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YGR049W ; YGR049W ; YGR049W .
GeneIDi 852940.
KEGGi sce:YGR049W.

Organism-specific databases

CYGDi YGR049w.
SGDi S000003281. SCM4.

Phylogenomic databases

eggNOGi NOG68417.
GeneTreei ENSGT00530000067118.
HOGENOMi HOG000000951.
OMAi TGITIFT.
OrthoDBi EOG7G7M1D.

Enzyme and pathway databases

BioCyci YEAST:G3O-30767-MONOMER.

Miscellaneous databases

NextBioi 972681.

Gene expression databases

Genevestigatori P32564.

Family and domain databases

ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "SCM4, a gene that suppresses mutant cdc4 function in budding yeast."
    Smith S.A., Kumar P., Johnston I., Rosamond J.
    Mol. Gen. Genet. 235:285-291(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Quantitative trait loci mapped to single-nucleotide resolution in yeast."
    Deutschbauer A.M., Davis R.W.
    Nat. Genet. 37:1333-1340(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: SK1.
  3. "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
    Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E.
    , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
    Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiSCM4_YEAST
AccessioniPrimary (citable) accession number: P32564
Secondary accession number(s): D6VUI6, Q45U35
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: May 14, 2014
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 3210 molecules/cell in log phase SD medium.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

External Data

Dasty 3

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