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Protein

Protein SCM4

Gene

SCM4

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciYEAST:G3O-30767-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein SCM4
Alternative name(s):
Suppressor of CDC4 mutation 4
Gene namesi
Name:SCM4
Ordered Locus Names:YGR049W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311 Componenti: Chromosome VII

Organism-specific databases

CYGDiYGR049w.
EuPathDBiFungiDB:YGR049W.
SGDiS000003281. SCM4.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei11 – 3121HelicalSequence AnalysisAdd
BLAST
Transmembranei45 – 6521HelicalSequence AnalysisAdd
BLAST
Transmembranei80 – 10021HelicalSequence AnalysisAdd
BLAST
Transmembranei162 – 18221HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 187187Protein SCM4PRO_0000097626Add
BLAST

Proteomic databases

MaxQBiP32564.
PaxDbiP32564.
PeptideAtlasiP32564.

Expressioni

Gene expression databases

GenevestigatoriP32564.

Interactioni

Protein-protein interaction databases

BioGridi33296. 6 interactions.
DIPiDIP-1870N.
IntActiP32564. 2 interactions.
MINTiMINT-408265.
STRINGi4932.YGR049W.

Structurei

3D structure databases

ProteinModelPortaliP32564.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATG33 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG68417.
GeneTreeiENSGT00530000067118.
HOGENOMiHOG000000951.
InParanoidiP32564.
OMAiTGITIFT.
OrthoDBiEOG7G7M1D.

Sequencei

Sequence statusi: Complete.

P32564-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQVSPAIVKG IAVSSLGLYA GILTSSTVIS ITTPINVLTQ HLKNVLCTLG
60 70 80 90 100
CWSTVLGGLA TGAFGLSYYL AAPGERPNYL LCGLGVAPLS AAYLYLVSLF
110 120 130 140 150
NHKLAPKCTR DQNDLEKQKD EKLPQHHPEV KDGEAACPFS KMNNAKTLKP
160 170 180
ESERSVKCHS YMSLHMSIVT GITIFTFGKC ILDGFKA
Length:187
Mass (Da):20,118
Last modified:October 1, 1993 - v1
Checksum:i6DE7C5C791B13568
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X69566 Genomic DNA. Translation: CAA49291.1.
DQ115391 Genomic DNA. Translation: AAZ22464.1.
Z72834 Genomic DNA. Translation: CAA97049.1.
BK006941 Genomic DNA. Translation: DAA08147.1.
PIRiS30093.
RefSeqiNP_011563.1. NM_001181178.1.

Genome annotation databases

EnsemblFungiiYGR049W; YGR049W; YGR049W.
GeneIDi852940.
KEGGisce:YGR049W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X69566 Genomic DNA. Translation: CAA49291.1.
DQ115391 Genomic DNA. Translation: AAZ22464.1.
Z72834 Genomic DNA. Translation: CAA97049.1.
BK006941 Genomic DNA. Translation: DAA08147.1.
PIRiS30093.
RefSeqiNP_011563.1. NM_001181178.1.

3D structure databases

ProteinModelPortaliP32564.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi33296. 6 interactions.
DIPiDIP-1870N.
IntActiP32564. 2 interactions.
MINTiMINT-408265.
STRINGi4932.YGR049W.

Proteomic databases

MaxQBiP32564.
PaxDbiP32564.
PeptideAtlasiP32564.

Protocols and materials databases

DNASUi852940.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYGR049W; YGR049W; YGR049W.
GeneIDi852940.
KEGGisce:YGR049W.

Organism-specific databases

CYGDiYGR049w.
EuPathDBiFungiDB:YGR049W.
SGDiS000003281. SCM4.

Phylogenomic databases

eggNOGiNOG68417.
GeneTreeiENSGT00530000067118.
HOGENOMiHOG000000951.
InParanoidiP32564.
OMAiTGITIFT.
OrthoDBiEOG7G7M1D.

Enzyme and pathway databases

BioCyciYEAST:G3O-30767-MONOMER.

Miscellaneous databases

NextBioi972681.
PROiP32564.

Gene expression databases

GenevestigatoriP32564.

Family and domain databases

ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "SCM4, a gene that suppresses mutant cdc4 function in budding yeast."
    Smith S.A., Kumar P., Johnston I., Rosamond J.
    Mol. Gen. Genet. 235:285-291(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Quantitative trait loci mapped to single-nucleotide resolution in yeast."
    Deutschbauer A.M., Davis R.W.
    Nat. Genet. 37:1333-1340(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: SK1.
  3. "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
    Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E.
    , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
    Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiSCM4_YEAST
AccessioniPrimary (citable) accession number: P32564
Secondary accession number(s): D6VUI6, Q45U35
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: April 29, 2015
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 3210 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.