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Protein

Chitinase 1

Gene

CHI1

Organism
Aphanocladium album (Wheat rust fungus) (Acremonium album)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei171Proton donorPROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCarbohydrate metabolism, Chitin degradation, Polysaccharide degradation

Protein family/group databases

CAZyiGH18. Glycoside Hydrolase Family 18.
mycoCLAPiCHI18A_APHAL.

Names & Taxonomyi

Protein namesi
Recommended name:
Chitinase 1 (EC:3.2.1.14)
Gene namesi
Name:CHI1
OrganismiAphanocladium album (Wheat rust fungus) (Acremonium album)
Taxonomic identifieri12942 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaAscomycota incertae sedisAphanocladium

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
PropeptideiPRO_000001192223 – 34Sequence analysisAdd BLAST12
ChainiPRO_000001192335 – 423Chitinase 1Add BLAST389

Keywords - PTMi

Cleavage on pair of basic residues, Zymogen

Structurei

3D structure databases

ProteinModelPortaliP32470.
SMRiP32470.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Family and domain databases

InterProiView protein in InterPro
IPR011583. Chitinase_II.
IPR029070. Chitinase_insertion.
IPR001223. Glyco_hydro18_cat.
IPR001579. Glyco_hydro_18_chit_AS.
IPR017853. Glycoside_hydrolase_SF.
PfamiView protein in Pfam
PF00704. Glyco_hydro_18. 1 hit.
SMARTiView protein in SMART
SM00636. Glyco_18. 1 hit.
SUPFAMiSSF51445. SSF51445. 2 hits.
SSF54556. SSF54556. 1 hit.
PROSITEiView protein in PROSITE
PS01095. CHITINASE_18. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P32470-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSFVKKSIA LVAALQAVTA LATPISSEAG VEKRGSGFAN AVYFTNWGIY
60 70 80 90 100
GRNFQPADLP ASEITHVLYS FMNVRADGTI FSGDTYADYE KHYAGDSWND
110 120 130 140 150
VGTNAYGCVK QLYLLKKQNR NMKVMLSIGG WTWSTNFPAA ASSAATRKTF
160 170 180 190 200
AQSAVGFMKD WGFDGIDIDW EYPADATQAQ NMVLLLQAVR SELDSYAAQY
210 220 230 240 250
AKGHHFLLSI AAPAGPDNYN KLKFAELGKV LDYINLMAYD YAGSWSNYTG
260 270 280 290 300
HDANIYANPQ NPNATPYNTD DAVQAYINGG VPANKIVLGM PIYGRSFQQT
310 320 330 340 350
EGIGKPYNGI GSGSWENGIW DYKALPKAGA TVKCDDTAKG CYSYDPSTKE
360 370 380 390 400
LISFDTPAMI STKVSWLKGK GLGGTMFWEA SASKKGSDSL ISTSHQGLGS
410 420
QDSTQNYLDY PNSKYDNIKK GMN
Length:423
Mass (Da):46,059
Last modified:February 1, 1996 - v2
Checksum:i55DFB25B73443F31
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X64104 Genomic DNA. Translation: CAA45468.1.
S81303 Genomic DNA. Translation: AAB21333.1.
PIRiJQ1975.
S26859.

Similar proteinsi

Entry informationi

Entry nameiCHI1_APHAL
AccessioniPrimary (citable) accession number: P32470
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: February 1, 1996
Last modified: October 25, 2017
This is version 95 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families