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Protein

Protein HYM1

Gene

HYM1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • budding cell apical bud growth Source: SGD
  • cell separation after cytokinesis Source: SGD
  • regulation of cell shape Source: SGD
  • regulation of transcription, DNA-templated Source: SGD
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-31952-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein HYM1
Gene namesi
Name:HYM1
Ordered Locus Names:YKL189W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311 Componenti: Chromosome XI

Organism-specific databases

CYGDiYKL189w.
EuPathDBiFungiDB:YKL189W.
SGDiS000001672. HYM1.

Subcellular locationi

GO - Cellular componenti

  • cellular bud Source: SGD
  • incipient cellular bud site Source: SGD
  • intracellular Source: SGD
  • mating projection tip Source: SGD
  • mitotic spindle pole body Source: CACAO
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 399399Protein HYM1PRO_0000209836Add
BLAST

Proteomic databases

MaxQBiP32464.
PaxDbiP32464.
PeptideAtlasiP32464.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
KIC1P386924EBI-8859,EBI-12253
SOG2Q088173EBI-8859,EBI-30849

Protein-protein interaction databases

BioGridi33933. 34 interactions.
DIPiDIP-5425N.
IntActiP32464. 8 interactions.
MINTiMINT-475734.
STRINGi4932.YKL189W.

Structurei

3D structure databases

ProteinModelPortaliP32464.
SMRiP32464. Positions 49-353.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Mo25 family.Curated

Phylogenomic databases

eggNOGiNOG307443.
GeneTreeiENSGT00390000004360.
HOGENOMiHOG000234711.
InParanoidiP32464.
KOiK08272.
OMAiCAEFLEA.
OrthoDBiEOG7VMPGS.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR028637. HymA.
IPR013878. Mo25.
[Graphical view]
PANTHERiPTHR10182. PTHR10182. 1 hit.
PTHR10182:SF3. PTHR10182:SF3. 1 hit.
PfamiPF08569. Mo25. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.

Sequencei

Sequence statusi: Complete.

P32464-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFKKYKNQDL DMAFWWKKNP KTPSDYARLI IEQLNKFSSP SLTQDNKRKV
60 70 80 90 100
QEECTKYLIG TKHFIVGDTD PHPTPEAIDE LYTAMHRADV FYELLLHFVD
110 120 130 140 150
LEFEARRECM LIFSICLGYS KDNKFVTVDY LVSQPKTISL MLRTAEVALQ
160 170 180 190 200
QKGCQDIFLT VGNMIIECIK YEQLCRIILK DPQLWKFFEF AKLGNFEIST
210 220 230 240 250
ESLQILSAAF TAHPKLVSKE FFSNEINIIR FIKCINKLMA HGSYVTKRQS
260 270 280 290 300
TKLLASLIVI RSNNALMNIY INSPENLKLI MTLMTDKSKN LQLEAFNVFK
310 320 330 340 350
VMVANPRKSK PVFDILVKNR DKLLTYFKTF GLDSQDSTFL DEREFIVQEI
360 370 380 390
DSLPRIISST TEVSNNNASS SNVASITSPS SVMNNQSSIL THSTSPDSR
Length:399
Mass (Da):45,853
Last modified:October 1, 1993 - v1
Checksum:iF48860754C892BA9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X69765 Genomic DNA. Translation: CAA49422.1.
X74151 Genomic DNA. Translation: CAA52249.1.
Z28189 Genomic DNA. Translation: CAA82032.1.
BK006944 Genomic DNA. Translation: DAA08977.1.
PIRiS34681.
RefSeqiNP_012732.1. NM_001179755.1.

Genome annotation databases

EnsemblFungiiYKL189W; YKL189W; YKL189W.
GeneIDi853646.
KEGGisce:YKL189W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X69765 Genomic DNA. Translation: CAA49422.1.
X74151 Genomic DNA. Translation: CAA52249.1.
Z28189 Genomic DNA. Translation: CAA82032.1.
BK006944 Genomic DNA. Translation: DAA08977.1.
PIRiS34681.
RefSeqiNP_012732.1. NM_001179755.1.

3D structure databases

ProteinModelPortaliP32464.
SMRiP32464. Positions 49-353.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi33933. 34 interactions.
DIPiDIP-5425N.
IntActiP32464. 8 interactions.
MINTiMINT-475734.
STRINGi4932.YKL189W.

Proteomic databases

MaxQBiP32464.
PaxDbiP32464.
PeptideAtlasiP32464.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYKL189W; YKL189W; YKL189W.
GeneIDi853646.
KEGGisce:YKL189W.

Organism-specific databases

CYGDiYKL189w.
EuPathDBiFungiDB:YKL189W.
SGDiS000001672. HYM1.

Phylogenomic databases

eggNOGiNOG307443.
GeneTreeiENSGT00390000004360.
HOGENOMiHOG000234711.
InParanoidiP32464.
KOiK08272.
OMAiCAEFLEA.
OrthoDBiEOG7VMPGS.

Enzyme and pathway databases

BioCyciYEAST:G3O-31952-MONOMER.

Miscellaneous databases

NextBioi974548.
PROiP32464.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR028637. HymA.
IPR013878. Mo25.
[Graphical view]
PANTHERiPTHR10182. PTHR10182. 1 hit.
PTHR10182:SF3. PTHR10182:SF3. 1 hit.
PfamiPF08569. Mo25. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "DNA sequence analysis of the YCN2 region of chromosome XI in Saccharomyces cerevisiae."
    Cheret G., Mattheakis L.C., Sor F.
    Yeast 9:661-667(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: S288c / GRF88.
  2. "Sequencing and analysis of 51.6 kilobases on the left arm of chromosome XI from Saccharomyces cerevisiae reveals 23 open reading frames including the FAS1 gene."
    Wiemann S., Voss H., Schwager C., Rupp T., Stegemann J., Zimmermann J., Grothues D., Sensen C., Erfle H., Hewitt N., Banrevi A., Ansorge W.
    Yeast 9:1343-1348(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  3. "Complete DNA sequence of yeast chromosome XI."
    Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C.
    , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W.
    Nature 369:371-378(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  5. "Roles for the Saccharomyces cerevisiae SDS3, CBK1 and HYM1 genes in transcriptional repression by SIN3."
    Dorland S., Deegenaars M.L., Stillman D.J.
    Genetics 154:573-586(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE NAME.
  6. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiHYM1_YEAST
AccessioniPrimary (citable) accession number: P32464
Secondary accession number(s): D6VX11
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: June 24, 2015
This is version 120 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 1280 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XI
    Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.