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P32464

- HYM1_YEAST

UniProt

P32464 - HYM1_YEAST

Protein

Protein HYM1

Gene

HYM1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 115 (01 Oct 2014)
      Sequence version 1 (01 Oct 1993)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. protein binding Source: IntAct

    GO - Biological processi

    1. budding cell apical bud growth Source: SGD
    2. cytokinesis, completion of separation Source: SGD
    3. regulation of cell shape Source: SGD
    4. regulation of transcription, DNA-templated Source: SGD

    Enzyme and pathway databases

    BioCyciYEAST:G3O-31952-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein HYM1
    Gene namesi
    Name:HYM1
    Ordered Locus Names:YKL189W
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome XI

    Organism-specific databases

    CYGDiYKL189w.
    SGDiS000001672. HYM1.

    Subcellular locationi

    GO - Cellular componenti

    1. cellular bud Source: SGD
    2. incipient cellular bud site Source: SGD
    3. intracellular Source: SGD
    4. mating projection tip Source: SGD

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 399399Protein HYM1PRO_0000209836Add
    BLAST

    Proteomic databases

    MaxQBiP32464.
    PaxDbiP32464.
    PeptideAtlasiP32464.

    Expressioni

    Gene expression databases

    GenevestigatoriP32464.

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    KIC1P386924EBI-8859,EBI-12253
    SOG2Q088173EBI-8859,EBI-30849

    Protein-protein interaction databases

    BioGridi33933. 33 interactions.
    DIPiDIP-5425N.
    IntActiP32464. 8 interactions.
    MINTiMINT-475734.
    STRINGi4932.YKL189W.

    Structurei

    3D structure databases

    ProteinModelPortaliP32464.
    SMRiP32464. Positions 49-353.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the Mo25 family.Curated

    Phylogenomic databases

    eggNOGiNOG307443.
    GeneTreeiENSGT00390000004360.
    HOGENOMiHOG000234711.
    KOiK08272.
    OMAiCKGYEHS.
    OrthoDBiEOG7VMPGS.

    Family and domain databases

    Gene3Di1.25.10.10. 1 hit.
    InterProiIPR011989. ARM-like.
    IPR016024. ARM-type_fold.
    IPR028637. HymA.
    IPR013878. Mo25.
    [Graphical view]
    PANTHERiPTHR10182. PTHR10182. 1 hit.
    PTHR10182:SF3. PTHR10182:SF3. 1 hit.
    PfamiPF08569. Mo25. 1 hit.
    [Graphical view]
    SUPFAMiSSF48371. SSF48371. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P32464-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFKKYKNQDL DMAFWWKKNP KTPSDYARLI IEQLNKFSSP SLTQDNKRKV    50
    QEECTKYLIG TKHFIVGDTD PHPTPEAIDE LYTAMHRADV FYELLLHFVD 100
    LEFEARRECM LIFSICLGYS KDNKFVTVDY LVSQPKTISL MLRTAEVALQ 150
    QKGCQDIFLT VGNMIIECIK YEQLCRIILK DPQLWKFFEF AKLGNFEIST 200
    ESLQILSAAF TAHPKLVSKE FFSNEINIIR FIKCINKLMA HGSYVTKRQS 250
    TKLLASLIVI RSNNALMNIY INSPENLKLI MTLMTDKSKN LQLEAFNVFK 300
    VMVANPRKSK PVFDILVKNR DKLLTYFKTF GLDSQDSTFL DEREFIVQEI 350
    DSLPRIISST TEVSNNNASS SNVASITSPS SVMNNQSSIL THSTSPDSR 399
    Length:399
    Mass (Da):45,853
    Last modified:October 1, 1993 - v1
    Checksum:iF48860754C892BA9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X69765 Genomic DNA. Translation: CAA49422.1.
    X74151 Genomic DNA. Translation: CAA52249.1.
    Z28189 Genomic DNA. Translation: CAA82032.1.
    BK006944 Genomic DNA. Translation: DAA08977.1.
    PIRiS34681.
    RefSeqiNP_012732.1. NM_001179755.1.

    Genome annotation databases

    EnsemblFungiiYKL189W; YKL189W; YKL189W.
    GeneIDi853646.
    KEGGisce:YKL189W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X69765 Genomic DNA. Translation: CAA49422.1 .
    X74151 Genomic DNA. Translation: CAA52249.1 .
    Z28189 Genomic DNA. Translation: CAA82032.1 .
    BK006944 Genomic DNA. Translation: DAA08977.1 .
    PIRi S34681.
    RefSeqi NP_012732.1. NM_001179755.1.

    3D structure databases

    ProteinModelPortali P32464.
    SMRi P32464. Positions 49-353.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 33933. 33 interactions.
    DIPi DIP-5425N.
    IntActi P32464. 8 interactions.
    MINTi MINT-475734.
    STRINGi 4932.YKL189W.

    Proteomic databases

    MaxQBi P32464.
    PaxDbi P32464.
    PeptideAtlasi P32464.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YKL189W ; YKL189W ; YKL189W .
    GeneIDi 853646.
    KEGGi sce:YKL189W.

    Organism-specific databases

    CYGDi YKL189w.
    SGDi S000001672. HYM1.

    Phylogenomic databases

    eggNOGi NOG307443.
    GeneTreei ENSGT00390000004360.
    HOGENOMi HOG000234711.
    KOi K08272.
    OMAi CKGYEHS.
    OrthoDBi EOG7VMPGS.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-31952-MONOMER.

    Miscellaneous databases

    NextBioi 974548.

    Gene expression databases

    Genevestigatori P32464.

    Family and domain databases

    Gene3Di 1.25.10.10. 1 hit.
    InterProi IPR011989. ARM-like.
    IPR016024. ARM-type_fold.
    IPR028637. HymA.
    IPR013878. Mo25.
    [Graphical view ]
    PANTHERi PTHR10182. PTHR10182. 1 hit.
    PTHR10182:SF3. PTHR10182:SF3. 1 hit.
    Pfami PF08569. Mo25. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48371. SSF48371. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "DNA sequence analysis of the YCN2 region of chromosome XI in Saccharomyces cerevisiae."
      Cheret G., Mattheakis L.C., Sor F.
      Yeast 9:661-667(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: S288c / GRF88.
    2. "Sequencing and analysis of 51.6 kilobases on the left arm of chromosome XI from Saccharomyces cerevisiae reveals 23 open reading frames including the FAS1 gene."
      Wiemann S., Voss H., Schwager C., Rupp T., Stegemann J., Zimmermann J., Grothues D., Sensen C., Erfle H., Hewitt N., Banrevi A., Ansorge W.
      Yeast 9:1343-1348(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    3. "Complete DNA sequence of yeast chromosome XI."
      Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C.
      , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W.
      Nature 369:371-378(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    5. "Roles for the Saccharomyces cerevisiae SDS3, CBK1 and HYM1 genes in transcriptional repression by SIN3."
      Dorland S., Deegenaars M.L., Stillman D.J.
      Genetics 154:573-586(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE NAME.
    6. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiHYM1_YEAST
    AccessioniPrimary (citable) accession number: P32464
    Secondary accession number(s): D6VX11
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1993
    Last sequence update: October 1, 1993
    Last modified: October 1, 2014
    This is version 115 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 1280 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome XI
      Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names

    External Data

    Dasty 3