Reviewed, UniProtKB/Swiss-Prot P32464 (HYM1_YEAST)

Names and origin

Protein names

Recommended name:
    Protein HYM1

Gene names

Name:	HYM1
Ordered Locus Names:	YKL189W

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	399 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Miscellaneous	Present with 1280 molecules/cell in log phase SD medium. Ref.5
Sequence similarities	Belongs to the Mo25 family.

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cell morphogenesis during vegetative growth Inferred from genetic interaction. Source: SGD cytokinesis, completion of separation Inferred from mutant phenotype. Source: SGD regulation of cell shape Inferred from genetic interaction. Source: SGD regulation of transcription Inferred from mutant phenotype. Source: SGD
Cellular component	cellular bud Inferred from direct assay. Source: SGD incipient cellular bud site Inferred from direct assay. Source: SGD mating projection tip Inferred from direct assay. Source: SGD
Molecular function	protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
KIC1	P38692	4	EBI-8859,EBI-12253
SOG2	Q08817	3	EBI-8859,EBI-30849

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 399	399	Protein HYM1		PRO_0000209836

Sequences

	Sequence		Length	Mass (Da)
	P32464-1 [UniParc]. Last modified October 1, 1993. Version 1. Checksum: F48860754C892BA9	FASTA	399	45,853
	10 20 30 40 50 60 MFKKYKNQDL DMAFWWKKNP KTPSDYARLI IEQLNKFSSP SLTQDNKRKV QEECTKYLIG 70 80 90 100 110 120 TKHFIVGDTD PHPTPEAIDE LYTAMHRADV FYELLLHFVD LEFEARRECM LIFSICLGYS 130 140 150 160 170 180 KDNKFVTVDY LVSQPKTISL MLRTAEVALQ QKGCQDIFLT VGNMIIECIK YEQLCRIILK 190 200 210 220 230 240 DPQLWKFFEF AKLGNFEIST ESLQILSAAF TAHPKLVSKE FFSNEINIIR FIKCINKLMA 250 260 270 280 290 300 HGSYVTKRQS TKLLASLIVI RSNNALMNIY INSPENLKLI MTLMTDKSKN LQLEAFNVFK 310 320 330 340 350 360 VMVANPRKSK PVFDILVKNR DKLLTYFKTF GLDSQDSTFL DEREFIVQEI DSLPRIISST 370 380 390 TEVSNNNASS SNVASITSPS SVMNNQSSIL THSTSPDSR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"DNA sequence analysis of the YCN2 region of chromosome XI in Saccharomyces cerevisiae." Cheret G., Mattheakis L.C., Sor F. Yeast 9:661-667(1993) [PubMed: 8394042] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: S288c / GRF88.
[2]	"Sequencing and analysis of 51.6 kilobases on the left arm of chromosome XI from Saccharomyces cerevisiae reveals 23 open reading frames including the FAS1 gene." Wiemann S., Voss H., Schwager C., Rupp T., Stegemann J., Zimmermann J., Grothues D., Sensen C., Erfle H., Hewitt N., Banrevi A., Ansorge W. Yeast 9:1343-1348(1993) [PubMed: 8154185] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]	"Complete DNA sequence of yeast chromosome XI." Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C. , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W. Nature 369:371-378(1994) [PubMed: 8196765] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[4]	"Roles for the Saccharomyces cerevisiae SDS3, CBK1 and HYM1 genes in transcriptional repression by SIN3." Dorland S., Deegenaars M.L., Stillman D.J. Genetics 154:573-586(2000) [PubMed: 10655212] [Abstract] Cited for: GENE NAME.
[5]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X69765 Genomic DNA. Translation: CAA49422.1. X74151 Genomic DNA. Translation: CAA52249.1. Z28189 Genomic DNA. Translation: CAA82032.1.
PIR	S34681.
RefSeq	NP_012732.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:5425N.
IntAct	P32464. 12 interactions.
STRING	P32464.
Proteomic databases
PeptideAtlas	P32464.
PRIDE	P32464.
Genome annotation databases
Ensembl	YKL189W; YKL189W; YKL189W; Saccharomyces cerevisiae. [Genome view]
GeneID	853646.
KEGG	sce:YKL189W.
NMPDR	fig|4932.3.peg.3709.
Organism-specific databases
CYGD	YKL189w.
SGD	S000001672. HYM1.
Phylogenomic databases
HOGENOM	P32464.
OMA	VANPRKS
OrthoDB	EOG9B5QNQ
Gene expression databases
ArrayExpress	P32464.
Genevestigator	P32464.
GermOnline	YKL189W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR016024. ARM-type_fold. IPR013878. Mo25. [Graphical view]
Pfam	PF08569. Mo25. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	974548.

Entry information

Entry name

HYM1_YEAST

Accession

Primary (citable) accession number: P32464

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1993
Last sequence update:	October 1, 1993
Last modified:	November 24, 2009
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)