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P32464

- HYM1_YEAST

UniProt

P32464 - HYM1_YEAST

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Protein

Protein HYM1

Gene
HYM1, YKL189W
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. protein binding Source: IntAct

GO - Biological processi

  1. budding cell apical bud growth Source: SGD
  2. cytokinesis, completion of separation Source: SGD
  3. regulation of cell shape Source: SGD
  4. regulation of transcription, DNA-templated Source: SGD
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-31952-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein HYM1
Gene namesi
Name:HYM1
Ordered Locus Names:YKL189W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome XI

Organism-specific databases

CYGDiYKL189w.
SGDiS000001672. HYM1.

Subcellular locationi

GO - Cellular componenti

  1. cellular bud Source: SGD
  2. incipient cellular bud site Source: SGD
  3. intracellular Source: SGD
  4. mating projection tip Source: SGD
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 399399Protein HYM1PRO_0000209836Add
BLAST

Proteomic databases

MaxQBiP32464.
PaxDbiP32464.
PeptideAtlasiP32464.

Expressioni

Gene expression databases

GenevestigatoriP32464.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
KIC1P386924EBI-8859,EBI-12253
SOG2Q088173EBI-8859,EBI-30849

Protein-protein interaction databases

BioGridi33933. 33 interactions.
DIPiDIP-5425N.
IntActiP32464. 8 interactions.
MINTiMINT-475734.
STRINGi4932.YKL189W.

Structurei

3D structure databases

ProteinModelPortaliP32464.
SMRiP32464. Positions 49-353.

Family & Domainsi

Sequence similaritiesi

Belongs to the Mo25 family.

Phylogenomic databases

eggNOGiNOG307443.
GeneTreeiENSGT00390000004360.
HOGENOMiHOG000234711.
KOiK08272.
OMAiCKGYEHS.
OrthoDBiEOG7VMPGS.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR028637. HymA.
IPR013878. Mo25.
[Graphical view]
PANTHERiPTHR10182. PTHR10182. 1 hit.
PTHR10182:SF3. PTHR10182:SF3. 1 hit.
PfamiPF08569. Mo25. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.

Sequencei

Sequence statusi: Complete.

P32464-1 [UniParc]FASTAAdd to Basket

« Hide

MFKKYKNQDL DMAFWWKKNP KTPSDYARLI IEQLNKFSSP SLTQDNKRKV    50
QEECTKYLIG TKHFIVGDTD PHPTPEAIDE LYTAMHRADV FYELLLHFVD 100
LEFEARRECM LIFSICLGYS KDNKFVTVDY LVSQPKTISL MLRTAEVALQ 150
QKGCQDIFLT VGNMIIECIK YEQLCRIILK DPQLWKFFEF AKLGNFEIST 200
ESLQILSAAF TAHPKLVSKE FFSNEINIIR FIKCINKLMA HGSYVTKRQS 250
TKLLASLIVI RSNNALMNIY INSPENLKLI MTLMTDKSKN LQLEAFNVFK 300
VMVANPRKSK PVFDILVKNR DKLLTYFKTF GLDSQDSTFL DEREFIVQEI 350
DSLPRIISST TEVSNNNASS SNVASITSPS SVMNNQSSIL THSTSPDSR 399
Length:399
Mass (Da):45,853
Last modified:October 1, 1993 - v1
Checksum:iF48860754C892BA9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X69765 Genomic DNA. Translation: CAA49422.1.
X74151 Genomic DNA. Translation: CAA52249.1.
Z28189 Genomic DNA. Translation: CAA82032.1.
BK006944 Genomic DNA. Translation: DAA08977.1.
PIRiS34681.
RefSeqiNP_012732.1. NM_001179755.1.

Genome annotation databases

EnsemblFungiiYKL189W; YKL189W; YKL189W.
GeneIDi853646.
KEGGisce:YKL189W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X69765 Genomic DNA. Translation: CAA49422.1 .
X74151 Genomic DNA. Translation: CAA52249.1 .
Z28189 Genomic DNA. Translation: CAA82032.1 .
BK006944 Genomic DNA. Translation: DAA08977.1 .
PIRi S34681.
RefSeqi NP_012732.1. NM_001179755.1.

3D structure databases

ProteinModelPortali P32464.
SMRi P32464. Positions 49-353.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 33933. 33 interactions.
DIPi DIP-5425N.
IntActi P32464. 8 interactions.
MINTi MINT-475734.
STRINGi 4932.YKL189W.

Proteomic databases

MaxQBi P32464.
PaxDbi P32464.
PeptideAtlasi P32464.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YKL189W ; YKL189W ; YKL189W .
GeneIDi 853646.
KEGGi sce:YKL189W.

Organism-specific databases

CYGDi YKL189w.
SGDi S000001672. HYM1.

Phylogenomic databases

eggNOGi NOG307443.
GeneTreei ENSGT00390000004360.
HOGENOMi HOG000234711.
KOi K08272.
OMAi CKGYEHS.
OrthoDBi EOG7VMPGS.

Enzyme and pathway databases

BioCyci YEAST:G3O-31952-MONOMER.

Miscellaneous databases

NextBioi 974548.

Gene expression databases

Genevestigatori P32464.

Family and domain databases

Gene3Di 1.25.10.10. 1 hit.
InterProi IPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR028637. HymA.
IPR013878. Mo25.
[Graphical view ]
PANTHERi PTHR10182. PTHR10182. 1 hit.
PTHR10182:SF3. PTHR10182:SF3. 1 hit.
Pfami PF08569. Mo25. 1 hit.
[Graphical view ]
SUPFAMi SSF48371. SSF48371. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "DNA sequence analysis of the YCN2 region of chromosome XI in Saccharomyces cerevisiae."
    Cheret G., Mattheakis L.C., Sor F.
    Yeast 9:661-667(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: S288c / GRF88.
  2. "Sequencing and analysis of 51.6 kilobases on the left arm of chromosome XI from Saccharomyces cerevisiae reveals 23 open reading frames including the FAS1 gene."
    Wiemann S., Voss H., Schwager C., Rupp T., Stegemann J., Zimmermann J., Grothues D., Sensen C., Erfle H., Hewitt N., Banrevi A., Ansorge W.
    Yeast 9:1343-1348(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  3. "Complete DNA sequence of yeast chromosome XI."
    Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C.
    , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W.
    Nature 369:371-378(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  5. "Roles for the Saccharomyces cerevisiae SDS3, CBK1 and HYM1 genes in transcriptional repression by SIN3."
    Dorland S., Deegenaars M.L., Stillman D.J.
    Genetics 154:573-586(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE NAME.
  6. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiHYM1_YEAST
AccessioniPrimary (citable) accession number: P32464
Secondary accession number(s): D6VX11
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: June 11, 2014
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 1280 molecules/cell in log phase SD medium.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XI
    Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names

External Data

Dasty 3

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