Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P32463

- ACPM_YEAST

UniProt

P32463 - ACPM_YEAST

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Acyl carrier protein, mitochondrial

Gene

ACP1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Carrier of the growing fatty acid chain in fatty acid biosynthesis By similarity. May be involved in the synthesis of very-long-chain fatty acids. Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain By similarity.By similarity

Pathwayi

GO - Molecular functioni

  1. ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process Source: SGD

GO - Biological processi

  1. lipoate biosynthetic process Source: SGD
  2. oxidation-reduction process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Respiratory chain, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-31954-MONOMER.
UniPathwayiUPA00094.

Names & Taxonomyi

Protein namesi
Recommended name:
Acyl carrier protein, mitochondrial
Short name:
ACP
Alternative name(s):
NADH-ubiquinone oxidoreductase 9.6 kDa subunit
Gene namesi
Name:ACP1
Ordered Locus Names:YKL192C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome XI

Organism-specific databases

CYGDiYKL192c.
SGDiS000001675. ACP1.

Subcellular locationi

GO - Cellular componenti

  1. mitochondrion Source: UniProtKB-KW
  2. respiratory chain Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 3636MitochondrionSequence AnalysisAdd
BLAST
Chaini37 – 12589Acyl carrier protein, mitochondrialPRO_0000000566Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei82 – 821O-(pantetheine 4'-phosphoryl)serineBy similarity

Post-translational modificationi

4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group By similarity.By similarity

Keywords - PTMi

Phosphopantetheine, Phosphoprotein

Proteomic databases

MaxQBiP32463.
PaxDbiP32463.
PeptideAtlasiP32463.

Expressioni

Gene expression databases

GenevestigatoriP32463.

Interactioni

Subunit structurei

Complex I is composed of about 30 different subunits.

Protein-protein interaction databases

BioGridi33929. 23 interactions.
DIPiDIP-3990N.
IntActiP32463. 2 interactions.
MINTiMINT-494746.
STRINGi4932.YKL192C.

Structurei

3D structure databases

ProteinModelPortaliP32463.
SMRiP32463. Positions 66-118.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 acyl carrier domain.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiCOG0236.
GeneTreeiENSGT00390000002127.
HOGENOMiHOG000178184.
InParanoidiP32463.
KOiK03955.
OMAiTASFAND.
OrthoDBiEOG757D9J.

Family and domain databases

Gene3Di1.10.1200.10. 1 hit.
HAMAPiMF_01217. Acyl_carrier.
InterProiIPR003231. Acyl_carrier.
IPR009081. Acyl_carrier_prot-like.
IPR006162. PPantetheine_attach_site.
[Graphical view]
PfamiPF00550. PP-binding. 1 hit.
[Graphical view]
ProDomiPD000887. PD000887. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF47336. SSF47336. 1 hit.
TIGRFAMsiTIGR00517. acyl_carrier. 1 hit.
PROSITEiPS50075. ACP_DOMAIN. 1 hit.
PS00012. PHOSPHOPANTETHEINE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P32463-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFRSVCRISS RVAPSAYRTI MGRSVMSNTI LAQRFYSANL SKDQVSQRVI
60 70 80 90 100
DVIKAFDKNS PNIANKQISS DTQFHKDLGL DSLDTVELLV AIEEEFDIEI
110 120
PDKVADELRS VGETVDYIAS NPDAN
Length:125
Mass (Da):13,943
Last modified:October 1, 1993 - v1
Checksum:iA0C64C5B796A5DDF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X69765 Genomic DNA. Translation: CAA49419.1.
Z28192 Genomic DNA. Translation: CAA82036.1.
AY558392 Genomic DNA. Translation: AAS56718.1.
BK006944 Genomic DNA. Translation: DAA08974.1.
PIRiS33960.
RefSeqiNP_012729.1. NM_001179758.1.

Genome annotation databases

EnsemblFungiiYKL192C; YKL192C; YKL192C.
GeneIDi853642.
KEGGisce:YKL192C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X69765 Genomic DNA. Translation: CAA49419.1 .
Z28192 Genomic DNA. Translation: CAA82036.1 .
AY558392 Genomic DNA. Translation: AAS56718.1 .
BK006944 Genomic DNA. Translation: DAA08974.1 .
PIRi S33960.
RefSeqi NP_012729.1. NM_001179758.1.

3D structure databases

ProteinModelPortali P32463.
SMRi P32463. Positions 66-118.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 33929. 23 interactions.
DIPi DIP-3990N.
IntActi P32463. 2 interactions.
MINTi MINT-494746.
STRINGi 4932.YKL192C.

Proteomic databases

MaxQBi P32463.
PaxDbi P32463.
PeptideAtlasi P32463.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YKL192C ; YKL192C ; YKL192C .
GeneIDi 853642.
KEGGi sce:YKL192C.

Organism-specific databases

CYGDi YKL192c.
SGDi S000001675. ACP1.

Phylogenomic databases

eggNOGi COG0236.
GeneTreei ENSGT00390000002127.
HOGENOMi HOG000178184.
InParanoidi P32463.
KOi K03955.
OMAi TASFAND.
OrthoDBi EOG757D9J.

Enzyme and pathway databases

UniPathwayi UPA00094 .
BioCyci YEAST:G3O-31954-MONOMER.

Miscellaneous databases

NextBioi 974537.
PROi P32463.

Gene expression databases

Genevestigatori P32463.

Family and domain databases

Gene3Di 1.10.1200.10. 1 hit.
HAMAPi MF_01217. Acyl_carrier.
InterProi IPR003231. Acyl_carrier.
IPR009081. Acyl_carrier_prot-like.
IPR006162. PPantetheine_attach_site.
[Graphical view ]
Pfami PF00550. PP-binding. 1 hit.
[Graphical view ]
ProDomi PD000887. PD000887. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SUPFAMi SSF47336. SSF47336. 1 hit.
TIGRFAMsi TIGR00517. acyl_carrier. 1 hit.
PROSITEi PS50075. ACP_DOMAIN. 1 hit.
PS00012. PHOSPHOPANTETHEINE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "DNA sequence analysis of the YCN2 region of chromosome XI in Saccharomyces cerevisiae."
    Cheret G., Mattheakis L.C., Sor F.
    Yeast 9:661-667(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: S288c / GRF88.
  2. "Complete DNA sequence of yeast chromosome XI."
    Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C.
    , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W.
    Nature 369:371-378(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiACPM_YEAST
AccessioniPrimary (citable) accession number: P32463
Secondary accession number(s): D6VX08
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: October 29, 2014
This is version 139 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 60500 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome XI
    Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names

External Data

Dasty 3