P32453 (ATP11_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein ATP11, mitochondrial

Gene names

Name:	ATP11
Ordered Locus Names:	YNL315C
ORF Names:	N0357

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	318 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Essential for the assembly of the mitochondrial F1-F0 complex. May interact with the alpha and/or beta subunits of F1-ATPase.
Subcellular location	Mitochondrion.
Miscellaneous	Present with 2840 molecules/cell in log phase SD medium. Ref.6
Sequence similarities	Belongs to the ATP11 family.

Ontologies

Keywords
Cellular component	Mitochondrion
Domain	Transit peptide
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	mitochondrial proton-transporting ATP synthase complex assembly Inferred from mutant phenotype. Source: SGD
Cellular component	mitochondrial matrix Traceable author statement. Source: SGD
Molecular function	unfolded protein binding Inferred from direct assay. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – ?40	40	Mitochondrion Potential
	Chain	?41 – 318	278	Protein ATP11, mitochondrial		PRO_0000002535
Amino acid modifications
	Modified residue	109	1	Phosphoserine Ref.7

Sequences

	Sequence		Length	Mass (Da)
	P32453 [UniParc]. Last modified October 1, 1993. Version 1. Checksum: 61109AA4D338F2CD	FASTA	318	36,851
	10 20 30 40 50 60 MWRLTRKIGT RIHISNQLSP IFNKAIGTVP VFRFYSSSPE QKYRKKLLEE AQKQGFNSIE 70 80 90 100 110 120 ELKNHLKETI ESKKREFNKI DPLKELEDYQ QKTQMENNNS KHLMTKSRSP LDPSAPKVPF 130 140 150 160 170 180 KTLDSFLDVG KLKDLSKQEV EFLWRARWAQ KDNTLCAVIP VSVYDKMMAN ARNNPIFVLP 190 200 210 220 230 240 LPRQVQSEDA KPNEEQGMEL HYIQWQFVGP QTTHCMMTSL AEYKLHQEFA RPHTTLQFHS 250 260 270 280 290 300 DLVKDKGIVF MNGHVEPDTN VNVQDAQLLL LNVQRFYGAM GEETPVAKQR VQLLRDFSKA 310 SPGFTVEKLI SLSQSMEN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Characterization of ATP11 and detection of the encoded protein in mitochondria of Saccharomyces cerevisiae." Ackerman S.H., Martin J., Tzagoloff A. J. Biol. Chem. 267:7386-7394(1992) [PubMed: 1532796] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Sequencing analysis of a 24.7 kb fragment of yeast chromosome XIV identifies six known genes, a new member of the hexose transporter family and ten new open reading frames." Maftahi M., Nicaud J.-M., Levesque H., Gaillardin C. Yeast 11:1077-1085(1995) [PubMed: 7502583] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: S288c / FY1676.
[3]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications." Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J. , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J. Nature 387:93-98(1997) [PubMed: 9169873] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[4]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[5]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[6]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[7]	"Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae." Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J., Elias J.E., Gygi S.P. J. Proteome Res. 6:1190-1197(2007) [PubMed: 17330950] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-109, MASS SPECTROMETRY. Strain: ADR376.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M87006 Genomic DNA. Translation: AAA34447.1. Z46259 Genomic DNA. Translation: CAA86381.1. Z71591 Genomic DNA. Translation: CAA96245.1. AY693039 Genomic DNA. Translation: AAT93058.1. BK006947 Genomic DNA. Translation: DAA10246.1.
PIR	S51297.
RefSeq	NP_014084.1. NM_001183153.1.
3D structure databases
ProteinModelPortal	P32453.
SMR	P32453. Positions 119-318.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-3026N.
IntAct	P32453. 7 interactions.
MINT	MINT-653373.
STRING	P32453.
Proteomic databases
PeptideAtlas	P32453.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YNL315C; YNL315C; YNL315C.
GeneID	855401.
KEGG	sce:YNL315C.
NMPDR	fig|4932.3.peg.5146.
Organism-specific databases
CYGD	YNL315c.
SGD	S000005259. ATP11.
Phylogenomic databases
eggNOG	fuNOG05612.
GeneTree	EFGT00050000005478.
HOGENOM	HBG397660.
OMA	NVQRFYG.
OrthoDB	EOG4SFDG5.
Gene expression databases
ArrayExpress	P32453.
Genevestigator	P32453.
GermOnline	YNL315C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR010591. ATP11. [Graphical view]
KO	K07555.
PANTHER	PTHR13126. ATP11. 1 hit.
Pfam	PF06644. ATP11. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	979226.

Entry information

Entry name

ATP11_YEAST

Accession

Primary (citable) accession number: P32453
Secondary accession number(s): D6W0N0

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1993
Last sequence update:	October 1, 1993
Last modified:	December 14, 2011
This is version 86 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program