Reviewed, UniProtKB/Swiss-Prot P32450 (AUA1_YEAST)

Names and origin

Protein names

Recommended name:
    Ammonia regulation of amino acid uptake protein

Gene names

Name:	AUA1
Ordered Locus Names:	YFL010W-A
ORF Names:	YFL010BW

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	94 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Involved in ammonia regulation of the GAP1 permease. Ref.1
Induction	Repressed in presence of ammonia. Ref.1

Ontologies

Keywords
Domain	Repeat
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	amino acid transport Ref.1 Inferred from mutant phenotype. Source: SGD
Molecular function	protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
ARGR2	P05085	1	EBI-2045077,EBI-2835

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 94	94	Ammonia regulation of amino acid uptake protein		PRO_0000064762
Regions
	Repeat	48 – 57	10
	Repeat	58 – 67	10
	Compositional bias	41 – 94	54	Arg/His/Lys-rich (basic)

Sequences

	Sequence		Length	Mass (Da)
	P32450-1 [UniParc]. Last modified October 1, 1993. Version 1. Checksum: 56F0ECA5A4F3C070	FASTA	94	11,722
	10 20 30 40 50 60 MDRSLQVYIC MYPYLDGSKQ YRFDELISFY RPCPKSLDNI KSHYRQIHHQ IRRRTHQHHQ 70 80 90 IRRRTHQHHH RSNCSRQRQC LVRHSCGRQM RVLA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"AUA1, a gene involved in ammonia regulation of amino acid transport in Saccharomyces cerevisiae." Sophianopoulou V., Diallinas G. Mol. Microbiol. 8:167-178(1993) [PubMed: 8497191] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, INDUCTION.
[2]	"Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae." Murakami Y., Naitou M., Hagiwara H., Shibata T., Ozawa M., Sasanuma S., Sasanuma M., Tsuchiya Y., Soeda E., Yokoyama K., Yamazaki M., Tashiro H., Eki T. Nat. Genet. 10:261-268(1995) [PubMed: 7670463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[3]	Barrell B.G., Churcher C., Rajandream M.A. Submitted (SEP-1994) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X69158 Genomic DNA. Translation: CAA48910.1. D50617 Genomic DNA. No translation available. Z46255 Genomic DNA. Translation: CAA86343.1.
PIR	S32939.
RefSeq	NP_116645.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:5756N.
IntAct	P32450. 2 interactions.
STRING	P32450.
Genome annotation databases
Ensembl	YFL010W-A; YFL010W-A; YFL010W-A; Saccharomyces cerevisiae. [Genome view]
GeneID	850537.
GenomeReviews	Gene locus YFL010W-A in contig D50617_GR.
KEGG	sce:YFL010W-A.
NMPDR	fig|4932.3.peg.2275.
Organism-specific databases
CYGD	YFL010w-a.
SGD	S000001955. AUA1.
Gene expression databases
ArrayExpress	P32450.
Genevestigator	P32450.
GermOnline	YFL010W-A. Saccharomyces cerevisiae.
Family and domain databases
ProtoNet	Search...
Other Resources
NextBio	966292.

Entry information

Entry name

AUA1_YEAST

Accession

Primary (citable) accession number: P32450

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1993
Last sequence update:	October 1, 1993
Last modified:	October 13, 2009
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)