Reviewed,
UniProtKB/Swiss-Prot P32445 (RIM1_YEAST)
Last modified
November 24, 2009.
Version 87.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Single-stranded DNA-binding protein RIM1, mitochondrial Alternative name(s): Mitochondrial ssDNA-binding protein | ||||||
| Gene names |
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| Organism | Saccharomyces cerevisiae (Baker's yeast) [Complete proteome] | ||||||
| Taxonomic identifier | 4932 [NCBI] | ||||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces |
Protein attributes
| Sequence length | 135 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | This protein binds preferentially and cooperatively to ss-DNA. Involved in mitochondrial DNA replication. |
| Subunit structure | Homotetramer. |
| Subcellular location | |
| Miscellaneous | Present with 3060 molecules/cell in log phase SD medium. Ref.4 |
| Sequence similarities | Contains 1 SSB domain. |
Ontologies
| Keywords | |
|---|---|
| Biological process | DNA replication |
| Cellular component | Mitochondrion |
| Domain | Transit peptide |
| Ligand | DNA-binding |
| Technical term | Complete proteome Direct protein sequencing |
| Gene Ontology (GO) | |
| Biological process | DNA replication Inferred from electronic annotation. Source: UniProtKB-KW mitochondrial genome maintenance Ref.1Inferred from mutant phenotype. Source: SGD |
| Cellular component | mitochondrial nucleoid Inferred from direct assay. Source: SGD |
| Molecular function | protein binding Inferred from physical interaction. Source: IntAct single-stranded DNA binding Ref.1Inferred from direct assay. Source: SGD |
| Complete GO annotation... | |
Binary interactions
Sequence annotation (Features)
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "A single-stranded DNA binding protein required for mitochondrial DNA replication in S. cerevisiae is homologous to E. coli SSB." van Dyck E., Foury F., Stillman B., Brill S.J. EMBO J. 11:3421-3430(1992) [PubMed: 1324172] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], PARTIAL PROTEIN SEQUENCE. |
| [2] | "Nucleotide sequence of 9.2 kb left of CRY1 on yeast chromosome III from strain AB972: evidence for a Ty insertion and functional analysis of open reading frame YCR28." Carbone M.L.A., Panzeri L., Falconi M.M., Carcano C., Plevani P., Lucchini G. Yeast 8:805-812(1992) [PubMed: 1332309] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972. |
| [3] | "The complete DNA sequence of yeast chromosome III." Oliver S.G., van der Aart Q.J.M., Agostoni-Carbone M.L., Aigle M., Alberghina L., Alexandraki D., Antoine G., Anwar R., Ballesta J.P.G., Benit P., Berben G., Bergantino E., Biteau N., Bolle P.-A., Bolotin-Fukuhara M., Brown A., Brown A.J.P., Buhler J.-M.  Sgouros J.G.Nature 357:38-46(1992) [PubMed: 1574125] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204508 / S288c. |
| [4] | "Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS]. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| S43128 Genomic DNA. Translation: AAB22978.1. S43129 mRNA. Translation: AAD13828.1. X59720 Genomic DNA. Translation: CAA42321.2. | |
| PIR | S23548. |
| RefSeq | NP_009958.2. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| DIP | DIP:7376N. |
| IntAct | P32445. 120 interactions. |
| STRING | P32445. |
Proteomic databases | |
| PeptideAtlas | P32445. |
| PRIDE | P32445. |
Genome annotation databases | |
| Ensembl | YCR028C-A; YCR028C-A; YCR028C-A; Saccharomyces cerevisiae. [Genome view] |
| GeneID | 850395. |
| KEGG | sce:YCR028C-A. |
| NMPDR | fig|4932.3.peg.683. |
Organism-specific databases | |
| CYGD | YCR028c-a. |
| SGD | S000007222. RIM1. |
Phylogenomic databases | |
| HOGENOM | P32445. |
| OMA | KYSIASQ |
| OrthoDB | EOG9X0P8T |
Gene expression databases | |
| ArrayExpress | P32445. |
| Genevestigator | P32445. |
| GermOnline | YCR028C-A. Saccharomyces cerevisiae. |
Family and domain databases | |
| InterPro | IPR012340. NA-bd_OB-fold. IPR016027. NA-bd_OB-fold-like. IPR000424. Primosome_PriB/ssb. IPR011344. ssDNA_bd. [Graphical view] |
| Gene3D | G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit. |
| PANTHER | PTHR10302. Single_strand_bd. 1 hit. |
| Pfam | PF00436. SSB. 1 hit. [Graphical view] |
| PROSITE | PS50935. SSB. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other Resources | |
| NextBio | 965920. |
Entry information
| Entry name | RIM1_YEAST | ||||||||
| Accession | Primary (citable) accession number: P32445 Secondary accession number(s): O11851 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |
| Yeast Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD |
| Yeast chromosome III Yeast (Saccharomyces cerevisiae) chromosome III: entries and gene names |
