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Protein

50S ribosomal protein L44e

Gene

rpl44e

Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Binds to the 23S rRNA. Binds deacetylated tRNA in the E site; when the tRNA binds a stretch of 7 amino acids are displaced to allow binding.

Cofactori

Zn2+CuratedNote: Binds 1 zinc ion per subunit.Curated

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi11ZincCurated1
Metal bindingi14ZincCurated1
Metal bindingi71ZincCurated1
Metal bindingi74ZincCurated1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri11 – 74C4-typeCuratedAdd BLAST64

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

Metal-binding, RNA-binding, rRNA-binding, tRNA-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L44eUniRule annotation
Alternative name(s):
HLA
La
Gene namesi
Name:rpl44eUniRule annotation
Ordered Locus Names:rrnAC3514
OrganismiHaloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Taxonomic identifieri272569 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHaloarcula
Proteomesi
  • UP000001169 Componenti: Chromosome I

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001491501 – 9250S ribosomal protein L44eAdd BLAST92

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Interacts weakly with protein L15e. Binds the E site tRNA.UniRule annotation4 Publications

Protein-protein interaction databases

STRINGi272569.rrnAC3514.

Structurei

Secondary structure

192
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi2 – 11Combined sources10
Turni12 – 15Combined sources4
Beta strandi16 – 24Combined sources9
Beta strandi32 – 34Combined sources3
Helixi35 – 43Combined sources9
Beta strandi45 – 47Combined sources3
Helixi50 – 53Combined sources4
Beta strandi61 – 63Combined sources3
Beta strandi67 – 71Combined sources5
Turni72 – 74Combined sources3
Beta strandi77 – 79Combined sources3
Beta strandi89 – 91Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1FFKX-ray2.40Z1-92[»]
1JJ2X-ray2.4021-92[»]
1K73X-ray3.0141-92[»]
1K8AX-ray3.0041-92[»]
1K9MX-ray3.0041-92[»]
1KC8X-ray3.0141-92[»]
1KD1X-ray3.0041-92[»]
1KQSX-ray3.1021-92[»]
1M1KX-ray3.2041-92[»]
1M90X-ray2.8041-92[»]
1N8RX-ray3.0041-92[»]
1NJIX-ray3.0041-92[»]
1Q7YX-ray3.2041-92[»]
1Q81X-ray2.9541-92[»]
1Q82X-ray2.9841-92[»]
1Q86X-ray3.0041-92[»]
1QVFX-ray3.1021-92[»]
1QVGX-ray2.9021-92[»]
1S72X-ray2.4031-92[»]
1VQ4X-ray2.7031-92[»]
1VQ5X-ray2.6031-92[»]
1VQ6X-ray2.7031-92[»]
1VQ7X-ray2.5031-92[»]
1VQ8X-ray2.2031-92[»]
1VQ9X-ray2.4031-92[»]
1VQKX-ray2.3031-92[»]
1VQLX-ray2.3031-92[»]
1VQMX-ray2.3031-92[»]
1VQNX-ray2.4031-92[»]
1VQOX-ray2.2031-92[»]
1VQPX-ray2.2531-92[»]
1W2BX-ray3.5021-92[»]
1YHQX-ray2.4031-92[»]
1YI2X-ray2.6531-92[»]
1YIJX-ray2.6031-92[»]
1YITX-ray2.8031-92[»]
1YJ9X-ray2.9031-92[»]
1YJNX-ray3.0031-92[»]
1YJWX-ray2.9031-92[»]
2OTJX-ray2.9031-92[»]
2OTLX-ray2.7031-92[»]
2QA4X-ray3.0031-92[»]
2QEXX-ray2.9031-92[»]
3CC2X-ray2.4031-92[»]
3CC4X-ray2.7031-92[»]
3CC7X-ray2.7031-92[»]
3CCEX-ray2.7531-92[»]
3CCJX-ray2.7031-92[»]
3CCLX-ray2.9031-92[»]
3CCMX-ray2.5531-92[»]
3CCQX-ray2.9031-92[»]
3CCRX-ray3.0031-92[»]
3CCSX-ray2.9531-92[»]
3CCUX-ray2.8031-92[»]
3CCVX-ray2.9031-92[»]
3CD6X-ray2.7531-92[»]
3CMAX-ray2.8031-92[»]
3CMEX-ray2.9531-92[»]
3CPWX-ray2.7021-92[»]
3CXCX-ray3.0021-92[»]
3G4SX-ray3.2031-92[»]
3G6EX-ray2.7031-92[»]
3G71X-ray2.8531-92[»]
3I55X-ray3.1131-92[»]
3I56X-ray2.9031-92[»]
3OW2X-ray2.7021-92[»]
4ADXelectron microscopy6.6031-92[»]
4V9FX-ray2.4031-92[»]
ProteinModelPortaliP32411.
SMRiP32411.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP32411.

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L44e family.UniRule annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri11 – 74C4-typeCuratedAdd BLAST64

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiarCOG04109. Archaea.
COG1631. LUCA.
HOGENOMiHOG000224988.
KOiK02929.
OMAiCNEHHEH.

Family and domain databases

Gene3Di3.10.450.80. 1 hit.
HAMAPiMF_01476. Ribosomal_L44e. 1 hit.
InterProiIPR000552. Ribosomal_L44e.
IPR011332. Ribosomal_zn-bd.
[Graphical view]
PfamiPF00935. Ribosomal_L44. 1 hit.
[Graphical view]
ProDomiPD002841. Ribosomal_L44e. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF57829. SSF57829. 1 hit.
PROSITEiPS01172. RIBOSOMAL_L44E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P32411-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQMPRRFNTY CPHCNEHQEH EVEKVRSGRQ TGMKWIDRQR ERNSGIGNDG
60 70 80 90
KFSKVPGGDK PTKKTDLKYR CGECGKAHLR EGWRAGRLEF QE
Length:92
Mass (Da):10,791
Last modified:October 1, 1993 - v1
Checksum:i14197AA6AE7AC07A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY596297 Genomic DNA. Translation: AAV48183.1.
PIRiS33790.
RefSeqiWP_004593654.1. NC_006396.1.

Genome annotation databases

EnsemblBacteriaiAAV48183; AAV48183; rrnAC3514.
GeneIDi3129532.
KEGGihma:rrnAC3514.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY596297 Genomic DNA. Translation: AAV48183.1.
PIRiS33790.
RefSeqiWP_004593654.1. NC_006396.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1FFKX-ray2.40Z1-92[»]
1JJ2X-ray2.4021-92[»]
1K73X-ray3.0141-92[»]
1K8AX-ray3.0041-92[»]
1K9MX-ray3.0041-92[»]
1KC8X-ray3.0141-92[»]
1KD1X-ray3.0041-92[»]
1KQSX-ray3.1021-92[»]
1M1KX-ray3.2041-92[»]
1M90X-ray2.8041-92[»]
1N8RX-ray3.0041-92[»]
1NJIX-ray3.0041-92[»]
1Q7YX-ray3.2041-92[»]
1Q81X-ray2.9541-92[»]
1Q82X-ray2.9841-92[»]
1Q86X-ray3.0041-92[»]
1QVFX-ray3.1021-92[»]
1QVGX-ray2.9021-92[»]
1S72X-ray2.4031-92[»]
1VQ4X-ray2.7031-92[»]
1VQ5X-ray2.6031-92[»]
1VQ6X-ray2.7031-92[»]
1VQ7X-ray2.5031-92[»]
1VQ8X-ray2.2031-92[»]
1VQ9X-ray2.4031-92[»]
1VQKX-ray2.3031-92[»]
1VQLX-ray2.3031-92[»]
1VQMX-ray2.3031-92[»]
1VQNX-ray2.4031-92[»]
1VQOX-ray2.2031-92[»]
1VQPX-ray2.2531-92[»]
1W2BX-ray3.5021-92[»]
1YHQX-ray2.4031-92[»]
1YI2X-ray2.6531-92[»]
1YIJX-ray2.6031-92[»]
1YITX-ray2.8031-92[»]
1YJ9X-ray2.9031-92[»]
1YJNX-ray3.0031-92[»]
1YJWX-ray2.9031-92[»]
2OTJX-ray2.9031-92[»]
2OTLX-ray2.7031-92[»]
2QA4X-ray3.0031-92[»]
2QEXX-ray2.9031-92[»]
3CC2X-ray2.4031-92[»]
3CC4X-ray2.7031-92[»]
3CC7X-ray2.7031-92[»]
3CCEX-ray2.7531-92[»]
3CCJX-ray2.7031-92[»]
3CCLX-ray2.9031-92[»]
3CCMX-ray2.5531-92[»]
3CCQX-ray2.9031-92[»]
3CCRX-ray3.0031-92[»]
3CCSX-ray2.9531-92[»]
3CCUX-ray2.8031-92[»]
3CCVX-ray2.9031-92[»]
3CD6X-ray2.7531-92[»]
3CMAX-ray2.8031-92[»]
3CMEX-ray2.9531-92[»]
3CPWX-ray2.7021-92[»]
3CXCX-ray3.0021-92[»]
3G4SX-ray3.2031-92[»]
3G6EX-ray2.7031-92[»]
3G71X-ray2.8531-92[»]
3I55X-ray3.1131-92[»]
3I56X-ray2.9031-92[»]
3OW2X-ray2.7021-92[»]
4ADXelectron microscopy6.6031-92[»]
4V9FX-ray2.4031-92[»]
ProteinModelPortaliP32411.
SMRiP32411.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272569.rrnAC3514.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAV48183; AAV48183; rrnAC3514.
GeneIDi3129532.
KEGGihma:rrnAC3514.

Phylogenomic databases

eggNOGiarCOG04109. Archaea.
COG1631. LUCA.
HOGENOMiHOG000224988.
KOiK02929.
OMAiCNEHHEH.

Miscellaneous databases

EvolutionaryTraceiP32411.

Family and domain databases

Gene3Di3.10.450.80. 1 hit.
HAMAPiMF_01476. Ribosomal_L44e. 1 hit.
InterProiIPR000552. Ribosomal_L44e.
IPR011332. Ribosomal_zn-bd.
[Graphical view]
PfamiPF00935. Ribosomal_L44. 1 hit.
[Graphical view]
ProDomiPD002841. Ribosomal_L44e. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF57829. SSF57829. 1 hit.
PROSITEiPS01172. RIBOSOMAL_L44E. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRL44E_HALMA
AccessioniPrimary (citable) accession number: P32411
Secondary accession number(s): Q5UX20
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: November 2, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.