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P32410 (RL37_HALMA) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 92. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
50S ribosomal protein L37e
Alternative name(s):
L35e
Gene names
Name:rpl37e
Ordered Locus Names:rrnAC0797.1
OrganismHaloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui) [Complete proteome] [HAMAP]
Taxonomic identifier272569 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHaloarcula

Protein attributes

Sequence length57 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Binds to the 23S rRNA. HAMAP-Rule MF_00547

Cofactor

Binds 1 zinc ion per subunit Probable.

Subunit structure

Part of the 50S ribosomal subunit. Interacts weakly with protein L4. Ref.3 Ref.4 Ref.5 Ref.6 Ref.7 Ref.8 Ref.9 Ref.10 Ref.11

Sequence similarities

Belongs to the ribosomal protein L37e family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed Ref.2
Chain2 – 575650S ribosomal protein L37e HAMAP-Rule MF_00547
PRO_0000139726

Regions

Zinc finger20 – 3819C4-type Probable

Sites

Metal binding201Zinc Probable
Metal binding231Zinc Probable
Metal binding351Zinc Probable
Metal binding381Zinc Probable

Secondary structure

................ 57
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P32410 [UniParc].

Last modified January 23, 2007. Version 2.
Checksum: A21A05AACA3112EC

FASTA576,314
        10         20         30         40         50 
MTGAGTPSQG KKNTTTHTKC RRCGEKSYHT KKKVCSSCGF GKSAKRRDYE WQSKAGE 

« Hide

References

« Hide 'large scale' references
[1]"Genome sequence of Haloarcula marismortui: a halophilic archaeon from the Dead Sea."
Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W., Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E., Hood L., Ng W.V.
Genome Res. 14:2221-2234(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
[2]"HL35e and HLA: primary structure of two very basic and cysteine-rich ribosomal proteins from Haloarcula marismortui."
Bergmann U., Wittmann-Liebold B.
Biochim. Biophys. Acta 1173:195-200(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 2-57.
[3]"The complete atomic structure of the large ribosomal subunit at 2.4 A resolution."
Ban N., Nissen P., Hansen J., Moore P.B., Steitz T.A.
Science 289:905-920(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF THE 50S SUBUNIT.
Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
[4]"The structural basis of ribosome activity in peptide bond synthesis."
Nissen P., Hansen J., Ban N., Moore P.B., Steitz T.A.
Science 289:920-930(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF THE 50S SUBUNIT.
Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
[5]"A pre-translocational intermediate in protein synthesis observed in crystals of enzymatically active 50S subunits."
Schmeing T.M., Seila A.C., Hansen J.L., Freeborn B., Soukup J.K., Scaringe S.A., Strobel S.A., Moore P.B., Steitz T.A.
Nat. Struct. Biol. 9:225-230(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.1 ANGSTROMS) OF THE 50S SUBUNIT.
Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
[6]"The kink-turn: a new RNA secondary structure motif."
Klein D.J., Schmeing T.M., Moore P.B., Steitz T.A.
EMBO J. 20:4214-4221(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF THE 50S SUBUNIT.
Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
[7]"The structures of four macrolide antibiotics bound to the large ribosomal subunit."
Hansen J.L., Ippolito J.A., Ban N., Nissen P., Moore P.B., Steitz T.A.
Mol. Cell 10:117-128(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH FOUR MACROLIDE ANTIBIOTICS.
Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
[8]"Structural insights into peptide bond formation."
Hansen J.L., Schmeing T.M., Moore P.B., Steitz T.A.
Proc. Natl. Acad. Sci. U.S.A. 99:11670-11675(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF THE 50S SUBUNIT.
Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
[9]"Structures of five antibiotics bound at the peptidyl transferase center of the large ribosomal subunit."
Hansen J.L., Moore P.B., Steitz T.A.
J. Mol. Biol. 330:1061-1075(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH FIVE ANTIBIOTICS AT THE PEPTIDYL TRANSFERASE CENTER.
Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
[10]"Structures of deacylated tRNA mimics bound to the E site of the large ribosomal subunit."
Schmeing T.M., Moore P.B., Steitz T.A.
RNA 9:1345-1352(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS) OF THE 50S SUBUNIT WITH TWO DIFFERENT E SITE SUBSTRATES.
[11]"Revisiting the Haloarcula marismortui 50S ribosomal subunit model."
Gabdulkhakov A., Nikonov S., Garber M.
Acta Crystallogr. D 69:997-1004(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF THE 50S SUBUNIT.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY596297 Genomic DNA. No translation available.
PIRS33789.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1FFKX-ray2.40X2-57[»]
1JJ2X-ray2.40Z2-57[»]
1K73X-ray3.0122-57[»]
1K8AX-ray3.0022-57[»]
1K9MX-ray3.0022-57[»]
1KC8X-ray3.0122-57[»]
1KD1X-ray3.0022-57[»]
1KQSX-ray3.10Z2-57[»]
1M1KX-ray3.2022-57[»]
1M90X-ray2.8022-57[»]
1N8RX-ray3.0022-57[»]
1NJIX-ray3.0022-57[»]
1Q7YX-ray3.2022-57[»]
1Q81X-ray2.9522-57[»]
1Q82X-ray2.9822-57[»]
1Q86X-ray3.0022-57[»]
1QVFX-ray3.10Z2-57[»]
1QVGX-ray2.90Z2-57[»]
1S72X-ray2.4011-57[»]
1VQ4X-ray2.7011-57[»]
1VQ5X-ray2.6011-57[»]
1VQ6X-ray2.7011-57[»]
1VQ7X-ray2.5011-57[»]
1VQ8X-ray2.2011-57[»]
1VQ9X-ray2.4011-57[»]
1VQKX-ray2.3011-57[»]
1VQLX-ray2.3011-57[»]
1VQMX-ray2.3011-57[»]
1VQNX-ray2.4011-57[»]
1VQOX-ray2.2011-57[»]
1VQPX-ray2.2511-57[»]
1W2BX-ray3.50Z2-57[»]
1YHQX-ray2.4011-57[»]
1YI2X-ray2.6511-57[»]
1YIJX-ray2.6011-57[»]
1YITX-ray2.8011-57[»]
1YJ9X-ray2.9011-57[»]
1YJNX-ray3.0011-57[»]
1YJWX-ray2.9011-57[»]
2OTJX-ray2.9011-57[»]
2OTLX-ray2.7011-57[»]
2QA4X-ray3.0011-57[»]
2QEXX-ray2.9011-57[»]
3CC2X-ray2.4011-57[»]
3CC4X-ray2.7011-57[»]
3CC7X-ray2.7011-57[»]
3CCEX-ray2.7511-57[»]
3CCJX-ray2.7011-57[»]
3CCLX-ray2.9011-57[»]
3CCMX-ray2.5511-57[»]
3CCQX-ray2.9011-57[»]
3CCRX-ray3.0011-57[»]
3CCSX-ray2.9511-57[»]
3CCUX-ray2.8011-57[»]
3CCVX-ray2.9011-57[»]
3CD6X-ray2.7511-57[»]
3CMAX-ray2.8011-57[»]
3CMEX-ray2.9511-57[»]
3CPWX-ray2.70Z1-57[»]
3CXCX-ray3.00Z2-57[»]
3G4SX-ray3.2012-57[»]
3G6EX-ray2.7012-57[»]
3G71X-ray2.8512-57[»]
3I55X-ray3.1111-57[»]
3I56X-ray2.9011-57[»]
3OW2X-ray2.70Z2-57[»]
4ADXelectron microscopy6.6011-57[»]
4HUBX-ray2.4011-57[»]
ProteinModelPortalP32410.
SMRP32410. Positions 2-57.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

CMRSearch...

Family and domain databases

Gene3D2.20.25.30. 1 hit.
HAMAPMF_00547. Ribosomal_L37e.
InterProIPR011331. Ribosomal_L37ae/L37e.
IPR001569. Ribosomal_L37e.
IPR018267. Ribosomal_L37e_CS.
IPR011332. Ribosomal_zn-bd.
[Graphical view]
PANTHERPTHR10768. PTHR10768. 1 hit.
PfamPF01907. Ribosomal_L37e. 1 hit.
[Graphical view]
ProDomPD005132. Ribosomal_L37e. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF57829. SSF57829. 1 hit.
PROSITEPS01077. RIBOSOMAL_L37E. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP32410.

Entry information

Entry nameRL37_HALMA
AccessionPrimary (citable) accession number: P32410
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: January 23, 2007
Last modified: July 9, 2014
This is version 92 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references