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Protein

54S ribosomal protein L41, mitochondrial

Gene

MRP20

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • RNA binding Source: GO_Central
  • structural constituent of ribosome Source: SGD

GO - Biological processi

  • mitochondrial translation Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-29949-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
54S ribosomal protein L41, mitochondrial
Alternative name(s):
YmL41
Gene namesi
Name:MRP20
Synonyms:MRPL41
Ordered Locus Names:YDR405W
ORF Names:D9509.23
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IV

Organism-specific databases

EuPathDBiFungiDB:YDR405W.
SGDiS000002813. MRP20.

Subcellular locationi

GO - Cellular componenti

  • mitochondrial large ribosomal subunit Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 4545Mitochondrion1 PublicationAdd
BLAST
Chaini46 – 26321854S ribosomal protein L41, mitochondrialPRO_0000030488Add
BLAST

Proteomic databases

MaxQBiP32387.

PTM databases

iPTMnetiP32387.

Interactioni

Subunit structurei

Component of the mitochondrial large ribosomal subunit. Mature mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S subunit contains at least 33 different proteins and 1 molecule of RNA (15S). The 54S subunit contains at least 45 different proteins and 1 molecule of RNA (21S). Interacts with the C-terminus of OXA1.3 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
MRPL40P365344EBI-15599,EBI-15595

Protein-protein interaction databases

BioGridi32465. 30 interactions.
DIPiDIP-6703N.
IntActiP32387. 9 interactions.
MINTiMINT-650158.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3J6Belectron microscopy3.20P1-263[»]
ProteinModelPortaliP32387.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L23P family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

HOGENOMiHOG000246534.
InParanoidiP32387.
KOiK02892.
OMAiLYFPKAR.
OrthoDBiEOG092C4LSY.

Family and domain databases

InterProiIPR012678. Ribosomal_L23/L15e_core_dom.
IPR013025. Ribosomal_L25/23.
[Graphical view]
PfamiPF00276. Ribosomal_L23. 1 hit.
[Graphical view]
SUPFAMiSSF54189. SSF54189. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P32387-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRLTVGTKN MLYPLQKTLA VGSCKPEQVP IRSLASVVES SSKILDKSGS
60 70 80 90 100
DREVDINVSE KIYKWTKAGI EQGKEHFKVG GNKVYFPKAR IILLRPNAKH
110 120 130 140 150
TPYQAKFIVP KSFNKLDLRD YLYHIYGLRA MNITTQLLHG KFNRMNLQTT
160 170 180 190 200
RFREPQIKKM TIEMEEPFIW PEEPRPDENS FWDSTTPDNM EKYREERLNC
210 220 230 240 250
LGSDANKPGT AFDGVVGPYE RVAQPFIPRF LKREIDNKRE RHAAELQRAD
260
KLIALNRYIE DLH
Length:263
Mass (Da):30,566
Last modified:October 1, 1993 - v1
Checksum:iB8B1E51BAC60C673
GO

Sequence cautioni

The sequence AAA34790 differs from that shown. Reason: Erroneous initiation. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti52 – 521R → Q AA sequence (PubMed:2060626).Curated
Sequence conflicti155 – 1551P → Y AA sequence (PubMed:9151978).Curated
Sequence conflicti253 – 2531I → K AA sequence (PubMed:9151978).Curated
Sequence conflicti259 – 2591I → K AA sequence (PubMed:9151978).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M81696 Genomic DNA. Translation: AAA34789.1.
M81696 Genomic DNA. Translation: AAA34790.1. Different initiation.
U32274 Genomic DNA. Translation: AAB64845.1.
BK006938 Genomic DNA. Translation: DAA12247.1.
PIRiB42105.
RefSeqiNP_010693.3. NM_001180713.3.

Genome annotation databases

EnsemblFungiiYDR405W; YDR405W; YDR405W.
GeneIDi852014.
KEGGisce:YDR405W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M81696 Genomic DNA. Translation: AAA34789.1.
M81696 Genomic DNA. Translation: AAA34790.1. Different initiation.
U32274 Genomic DNA. Translation: AAB64845.1.
BK006938 Genomic DNA. Translation: DAA12247.1.
PIRiB42105.
RefSeqiNP_010693.3. NM_001180713.3.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3J6Belectron microscopy3.20P1-263[»]
ProteinModelPortaliP32387.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi32465. 30 interactions.
DIPiDIP-6703N.
IntActiP32387. 9 interactions.
MINTiMINT-650158.

PTM databases

iPTMnetiP32387.

Proteomic databases

MaxQBiP32387.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYDR405W; YDR405W; YDR405W.
GeneIDi852014.
KEGGisce:YDR405W.

Organism-specific databases

EuPathDBiFungiDB:YDR405W.
SGDiS000002813. MRP20.

Phylogenomic databases

HOGENOMiHOG000246534.
InParanoidiP32387.
KOiK02892.
OMAiLYFPKAR.
OrthoDBiEOG092C4LSY.

Enzyme and pathway databases

BioCyciYEAST:G3O-29949-MONOMER.

Miscellaneous databases

PROiP32387.

Family and domain databases

InterProiIPR012678. Ribosomal_L23/L15e_core_dom.
IPR013025. Ribosomal_L25/23.
[Graphical view]
PfamiPF00276. Ribosomal_L23. 1 hit.
[Graphical view]
SUPFAMiSSF54189. SSF54189. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRM41_YEAST
AccessioniPrimary (citable) accession number: P32387
Secondary accession number(s): D6VT37
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: September 7, 2016
This is version 144 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 2200 molecules/cell in log phase SD medium.1 Publication

Caution

It is uncertain whether Met-1 or Met-11 is the initiator.Curated

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families
  4. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  5. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.