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Protein

Mitochondrial oxaloacetate transport protein

Gene

OAC1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Transports oxaloacetate and sulfate.

Miscellaneous

Present with 5350 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • isopropylmalate transmembrane transporter activity Source: SGD
  • malonate(1-) transmembrane transporter activity Source: SGD
  • oxaloacetate transmembrane transporter activity Source: SGD
  • sulfate transmembrane transporter activity Source: SGD

GO - Biological processi

  • isopropylmalate transport Source: SGD
  • mitochondrial transport Source: GO_Central
  • oxaloacetate transport Source: SGD
  • sulfate transport Source: SGD

Keywordsi

Biological processTransport

Enzyme and pathway databases

BioCyciYEAST:G3O-31903-MONOMER

Protein family/group databases

TCDBi2.A.29.15.1 the mitochondrial carrier (mc) family

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial oxaloacetate transport protein
Alternative name(s):
Mitochondrial carrier protein PMT
Gene namesi
Name:OAC1
Synonyms:PMT, PMT1
Ordered Locus Names:YKL120W
ORF Names:YKL522
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi

Organism-specific databases

EuPathDBiFungiDB:YKL120W
SGDiS000001603 OAC1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei26 – 46Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei79 – 99Helical; Name=2Sequence analysisAdd BLAST21
Transmembranei132 – 152Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei193 – 213Helical; Name=4Sequence analysisAdd BLAST21
Transmembranei233 – 253Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei284 – 305Helical; Name=6Sequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000906891 – 324Mitochondrial oxaloacetate transport proteinAdd BLAST324

Proteomic databases

MaxQBiP32332
PaxDbiP32332
PRIDEiP32332

Interactioni

Protein-protein interaction databases

BioGridi34015, 89 interactors
DIPiDIP-5417N
IntActiP32332, 5 interactors
MINTiP32332
STRINGi4932.YKL120W

Structurei

3D structure databases

ProteinModelPortaliP32332
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati20 – 111Solcar 1Add BLAST92
Repeati126 – 218Solcar 2Add BLAST93
Repeati227 – 312Solcar 3Add BLAST86

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00550000074760
HOGENOMiHOG000165141
InParanoidiP32332
KOiK15117
OMAiQFFMNGV
OrthoDBiEOG092C3R1T

Family and domain databases

Gene3Di1.50.40.10, 1 hit
InterProiView protein in InterPro
IPR002067 Mit_carrier
IPR018108 Mitochondrial_sb/sol_carrier
IPR023395 Mt_carrier_dom_sf
PfamiView protein in Pfam
PF00153 Mito_carr, 3 hits
PRINTSiPR00926 MITOCARRIER
SUPFAMiSSF103506 SSF103506, 1 hit
PROSITEiView protein in PROSITE
PS50920 SOLCAR, 3 hits

Sequencei

Sequence statusi: Complete.

P32332-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSDNSKQDK QIEKTAAQKI SKFGSFVAGG LAACIAVTVT NPIELIKIRM
60 70 80 90 100
QLQGEMSASA AKVYKNPIQG MAVIFKNEGI KGLQKGLNAA YIYQIGLNGS
110 120 130 140 150
RLGFYEPIRS SLNQLFFPDQ EPHKVQSVGV NVFSGAASGI IGAVIGSPLF
160 170 180 190 200
LVKTRLQSYS EFIKIGEQTH YTGVWNGLVT IFKTEGVKGL FRGIDAAILR
210 220 230 240 250
TGAGSSVQLP IYNTAKNILV KNDLMKDGPA LHLTASTISG LGVAVVMNPW
260 270 280 290 300
DVILTRIYNQ KGDLYKGPID CLVKTVRIEG VTALYKGFAA QVFRIAPHTI
310 320
MCLTFMEQTM KLVYSIESRV LGHN
Length:324
Mass (Da):35,153
Last modified:October 1, 1993 - v1
Checksum:i696193F8979266AE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L04948 Genomic DNA Translation: AAA34886.1
AJ238698 Genomic DNA Translation: CAB52216.1
S44213 Genomic DNA Translation: AAB23071.2
Z28120 Genomic DNA Translation: CAA81961.1
BK006944 Genomic DNA Translation: DAA09040.1
PIRiS25357
RefSeqiNP_012802.1, NM_001179686.1

Genome annotation databases

EnsemblFungiiYKL120W; YKL120W; YKL120W
GeneIDi853739
KEGGisce:YKL120W

Similar proteinsi

Entry informationi

Entry nameiOAC1_YEAST
AccessioniPrimary (citable) accession number: P32332
Secondary accession number(s): D6VXH0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: May 23, 2018
This is version 152 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XI
    Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names

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