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Protein

Carrier protein YMC1, mitochondrial

Gene

YMC1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  • glycine transmembrane transporter activity Source: SGD
  • organic acid transmembrane transporter activity Source: SGD

GO - Biological processi

  • glycine import Source: SGD
  • mitochondrial transport Source: SGD
  • organic acid transmembrane transport Source: GOC
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-34210-MONOMER.

Protein family/group databases

TCDBi2.A.29.8.12. the mitochondrial carrier (mc) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Carrier protein YMC1, mitochondrial
Gene namesi
Name:YMC1
Ordered Locus Names:YPR058W
ORF Names:YP9499.14
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XVI

Organism-specific databases

EuPathDBiFungiDB:YPR058W.
SGDiS000006262. YMC1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei29 – 4921Helical; Name=1Sequence analysisAdd
BLAST
Transmembranei83 – 10321Helical; Name=2Sequence analysisAdd
BLAST
Transmembranei118 – 13821Helical; Name=3Sequence analysisAdd
BLAST
Transmembranei183 – 20321Helical; Name=4Sequence analysisAdd
BLAST
Transmembranei223 – 24321Helical; Name=5Sequence analysisAdd
BLAST
Transmembranei277 – 29822Helical; Name=6Sequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • mitochondrial inner membrane Source: UniProtKB-SubCell
  • mitochondrion Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini? – 307Carrier protein YMC1, mitochondrialPRO_0000019265
Transit peptidei1 – ?MitochondrionSequence analysis

Proteomic databases

MaxQBiP32331.
PeptideAtlasiP32331.

Interactioni

Protein-protein interaction databases

BioGridi36232. 24 interactions.
DIPiDIP-3895N.
IntActiP32331. 1 interaction.
MINTiMINT-544949.

Structurei

3D structure databases

ProteinModelPortaliP32331.
SMRiP32331. Positions 26-306.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati26 – 10681Solcar 1Add
BLAST
Repeati121 – 20484Solcar 2Add
BLAST
Repeati218 – 30588Solcar 3Add
BLAST

Sequence similaritiesi

Contains 3 Solcar repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00840000130868.
HOGENOMiHOG000168307.
InParanoidiP32331.
KOiK15109.
OMAiALMEVEH.
OrthoDBiEOG74TX8V.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
[Graphical view]
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P32331-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEEFPSPQL IDDLEEHPQH DNARVVKDLL AGTAGGIAQV LVGQPFDTTK
60 70 80 90 100
VRLQTSSTPT TAMEVVRKLL ANEGPRGFYK GTLTPLIGVG ACVSLQFGVN
110 120 130 140 150
EAMKRFFHHR NADMSSTLSL PQYYACGVTG GIVNSFLASP IEHVRIRLQT
160 170 180 190 200
QTGSGTNAEF KGPLECIKKL RHNKALLRGL TPTILREGHG CGTYFLVYEA
210 220 230 240 250
LIANQMNKRR GLERKDIPAW KLCIFGALSG TALWLMVYPL DVIKSVMQTD
260 270 280 290 300
NLQKPKFGNS ISSVAKTLYA NGGIGAFFKG FGPTMLRAAP ANGATFATFE

LAMRLLG
Length:307
Mass (Da):33,376
Last modified:September 26, 2001 - v2
Checksum:i106C1464B8DCC09A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti101 – 1011E → Q in CAA47602 (PubMed:8488731).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X67122 Genomic DNA. Translation: CAA47602.1.
Z71255 Genomic DNA. Translation: CAA95003.1.
Z49219 Genomic DNA. Translation: CAA89176.1.
BK006949 Genomic DNA. Translation: DAA11480.1.
PIRiS54080.
RefSeqiNP_015383.1. NM_001184155.1.

Genome annotation databases

EnsemblFungiiYPR058W; YPR058W; YPR058W.
GeneIDi856171.
KEGGisce:YPR058W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X67122 Genomic DNA. Translation: CAA47602.1.
Z71255 Genomic DNA. Translation: CAA95003.1.
Z49219 Genomic DNA. Translation: CAA89176.1.
BK006949 Genomic DNA. Translation: DAA11480.1.
PIRiS54080.
RefSeqiNP_015383.1. NM_001184155.1.

3D structure databases

ProteinModelPortaliP32331.
SMRiP32331. Positions 26-306.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi36232. 24 interactions.
DIPiDIP-3895N.
IntActiP32331. 1 interaction.
MINTiMINT-544949.

Protein family/group databases

TCDBi2.A.29.8.12. the mitochondrial carrier (mc) family.

Proteomic databases

MaxQBiP32331.
PeptideAtlasiP32331.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYPR058W; YPR058W; YPR058W.
GeneIDi856171.
KEGGisce:YPR058W.

Organism-specific databases

EuPathDBiFungiDB:YPR058W.
SGDiS000006262. YMC1.

Phylogenomic databases

GeneTreeiENSGT00840000130868.
HOGENOMiHOG000168307.
InParanoidiP32331.
KOiK15109.
OMAiALMEVEH.
OrthoDBiEOG74TX8V.

Enzyme and pathway databases

BioCyciYEAST:G3O-34210-MONOMER.

Miscellaneous databases

NextBioi981328.
PROiP32331.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
[Graphical view]
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "YMC1, a yeast gene encoding a new putative mitochondrial carrier protein."
    Graf R., Baum B., Braus G.H.
    Yeast 9:301-305(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI."
    Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W., Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D., Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E., Churcher C.M.
    , Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H., DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N., Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K., Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M., Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A., Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S., Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D., Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S., Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B., Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A., Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R., Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A., Vo D.H., Hani J.
    Nature 387:103-105(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.

Entry informationi

Entry nameiYMC1_YEAST
AccessioniPrimary (citable) accession number: P32331
Secondary accession number(s): D6W464, Q12002
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: September 26, 2001
Last modified: May 11, 2016
This is version 133 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XVI
    Yeast (Saccharomyces cerevisiae) chromosome XVI: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.