P32331 (YMC1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Carrier protein YMC1, mitochondrial

Gene names

Name:	YMC1
Ordered Locus Names:	YPR058W
ORF Names:	YP9499.14

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	307 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Mitochondrion inner membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the mitochondrial carrier family. Contains 3 Solcar repeats.

Ontologies

Keywords
Biological process	Transport
Cellular component	Membrane Mitochondrion Mitochondrion inner membrane
Domain	Repeat Transit peptide Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW mitochondrial inner membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – ?		Mitochondrion Potential
	Chain	? – 307		Carrier protein YMC1, mitochondrial		PRO_0000019265
Regions
	Transmembrane	29 – 49	21	Helical; Name=1; Potential
	Transmembrane	83 – 103	21	Helical; Name=2; Potential
	Transmembrane	118 – 138	21	Helical; Name=3; Potential
	Transmembrane	183 – 203	21	Helical; Name=4; Potential
	Transmembrane	223 – 243	21	Helical; Name=5; Potential
	Transmembrane	277 – 298	22	Helical; Name=6; Potential
	Repeat	26 – 106	81	Solcar 1
	Repeat	121 – 204	84	Solcar 2
	Repeat	218 – 305	88	Solcar 3
Experimental info
	Sequence conflict	101	1	E → Q in CAA47602. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P32331 [UniParc]. Last modified September 26, 2001. Version 2. Checksum: 106C1464B8DCC09A	FASTA	307	33,376
	10 20 30 40 50 60 MSEEFPSPQL IDDLEEHPQH DNARVVKDLL AGTAGGIAQV LVGQPFDTTK VRLQTSSTPT 70 80 90 100 110 120 TAMEVVRKLL ANEGPRGFYK GTLTPLIGVG ACVSLQFGVN EAMKRFFHHR NADMSSTLSL 130 140 150 160 170 180 PQYYACGVTG GIVNSFLASP IEHVRIRLQT QTGSGTNAEF KGPLECIKKL RHNKALLRGL 190 200 210 220 230 240 TPTILREGHG CGTYFLVYEA LIANQMNKRR GLERKDIPAW KLCIFGALSG TALWLMVYPL 250 260 270 280 290 300 DVIKSVMQTD NLQKPKFGNS ISSVAKTLYA NGGIGAFFKG FGPTMLRAAP ANGATFATFE LAMRLLG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"YMC1, a yeast gene encoding a new putative mitochondrial carrier protein." Graf R., Baum B., Braus G.H. Yeast 9:301-305(1993) [PubMed: 8488731] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI." Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W., Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D., Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E., Churcher C.M. , Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H., DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N., Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K., Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M., Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A., Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S., Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D., Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S., Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B., Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A., Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R., Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A., Vo D.H., Hani J. Nature 387:103-105(1997) [PubMed: 9169875] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[3]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X67122 Genomic DNA. Translation: CAA47602.1. Z71255 Genomic DNA. Translation: CAA95003.1. Z49219 Genomic DNA. Translation: CAA89176.1. BK006949 Genomic DNA. Translation: DAA11480.1.
PIR	S54080.
RefSeq	NP_015383.1. NM_001184155.1.
3D structure databases
ProteinModelPortal	P32331.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-3895N.
MINT	MINT-544949.
STRING	P32331.
Proteomic databases
PeptideAtlas	P32331.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YPR058W; YPR058W; YPR058W.
GeneID	856171.
KEGG	sce:YPR058W.
NMPDR	fig|4932.3.peg.6519.
Organism-specific databases
CYGD	YPR058w.
SGD	S000006262. YMC1.
Phylogenomic databases
eggNOG	fuNOG07705.
GeneTree	EFGT00050000002383.
HOGENOM	HBG735918.
OMA	AVVEMTM.
OrthoDB	EOG4CJZS2.
Gene expression databases
ArrayExpress	P32331.
Genevestigator	P32331.
GermOnline	YPR058W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR018108. Mitochondrial_sb/sol_carrier. IPR023395. Mt_carrier_dom. [Graphical view]
Gene3D	G3DSA:1.50.40.10. G3DSA:1.50.40.10. 1 hit.
KO	K15109.
Pfam	PF00153. Mito_carr. 3 hits. [Graphical view]
SUPFAM	SSF103506. Mitoch_carrier. 1 hit.
PROSITE	PS50920. SOLCAR. 3 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	981328.

Entry information

Entry name

YMC1_YEAST

Accession

Primary (citable) accession number: P32331
Secondary accession number(s): D6W464, Q12002

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1993
Last sequence update:	September 26, 2001
Last modified:	December 14, 2011
This is version 97 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program