P32241 (VIPR1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Vasoactive intestinal polypeptide receptor 1
Short name=VIP-R-1

Alternative name(s):
Pituitary adenylate cyclase-activating polypeptide type II receptor
Short name=PACAP type II receptor
Short name=PACAP-R-2
Short name=PACAP-R2
VPAC1

Gene names

Name:

VIPR1

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	457 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	This is a receptor for VIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The affinity is VIP = PACAP-27 > PACAP-38. Ref.11
Subcellular location	Cell membrane; Multi-pass membrane protein.
Tissue specificity	In lung, HT-29 colonic epithelial cells, Raji B-lymphoblasts. Lesser extent in brain, heart, kidney, liver and placenta. Not expressed in CD4+ or CD8+ T-cells. Expressed in the T-cell lines HARRIS, HuT 78, Jurkat and SUP-T1, but not in the T-cell lines Peer, MOLT-4, HSB and YT. Ref.11
Sequence similarities	Belongs to the G-protein coupled receptor 2 family.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Signal Transmembrane Transmembrane helix
Molecular function	G-protein coupled receptor Receptor Transducer
PTM	Disulfide bond Glycoprotein Phosphoprotein
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger Traceable author statement Ref.1. Source: ProtInc digestion Traceable author statement Ref.1. Source: ProtInc immune response Traceable author statement Ref.1. Source: ProtInc muscle contraction Traceable author statement Ref.1. Source: ProtInc positive regulation of cell proliferation Traceable author statement PubMed 8389448. Source: ProtInc synaptic transmission Traceable author statement Ref.1. Source: ProtInc
Cellular_component	cytoplasm Inferred from direct assay. Source: HPA integral to plasma membrane Traceable author statement Ref.2. Source: ProtInc nucleus Inferred from direct assay. Source: HPA
Molecular_function	vasoactive intestinal polypeptide receptor activity Traceable author statement Ref.2. Source: ProtInc
Complete GO annotation...

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform Short (identifier: P32241-1)

Also known as: hIVR8;

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform Long (identifier: P32241-2)

Also known as: hIVR5;

The sequence of this isoform differs from the canonical sequence as follows:
     1-32: MRPPSPLPARWLCVLAGALAWALGPAGGQAAR → MPPPPLLSLR...RAARSLLGSS

Isoform 3 (identifier: P32241-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-263: MRPPSPLPAR...YFWGYILIGW → MTRQRVWMRW...PSSLSGSTSG

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 30	30	Potential
	Chain	31 – 457	427	Vasoactive intestinal polypeptide receptor 1		PRO_0000012855
Regions
	Topological domain	31 – 142	112	Extracellular Potential
	Transmembrane	143 – 167	25	Helical; Name=1; Potential
	Topological domain	168 – 174	7	Cytoplasmic Potential
	Transmembrane	175 – 194	20	Helical; Name=2; Potential
	Topological domain	195 – 216	22	Extracellular Potential
	Transmembrane	217 – 240	24	Helical; Name=3; Potential
	Topological domain	241 – 254	14	Cytoplasmic Potential
	Transmembrane	255 – 276	22	Helical; Name=4; Potential
	Topological domain	277 – 292	16	Extracellular Potential
	Transmembrane	293 – 316	24	Helical; Name=5; Potential
	Topological domain	317 – 341	25	Cytoplasmic Potential
	Transmembrane	342 – 361	20	Helical; Name=6; Potential
	Topological domain	362 – 373	12	Extracellular Potential
	Transmembrane	374 – 393	20	Helical; Name=7; Potential
	Topological domain	394 – 457	64	Cytoplasmic Potential
Amino acid modifications
	Modified residue	449	1	Phosphoserine By similarity
	Modified residue	455	1	Phosphoserine By similarity
	Glycosylation	58	1	N-linked (GlcNAc...) Potential
	Glycosylation	69	1	N-linked (GlcNAc...) Potential
	Glycosylation	100	1	N-linked (GlcNAc...) Potential
	Glycosylation	290	1	N-linked (GlcNAc...) Potential
	Disulfide bond	50 ↔ 72		By similarity
	Disulfide bond	63 ↔ 105		By similarity
	Disulfide bond	86 ↔ 122		By similarity
	Disulfide bond	215 ↔ 285		Ref.12
Natural variations
	Alternative sequence	1 – 263	263	MRPPS…ILIGW → MTRQRVWMRWAVRQPWSFSN IVSWLTSSGCWWRASTCTPC LPSPSSLSGSTSG in isoform 3.		VSP_045143
	Alternative sequence	1 – 32	32	MRPPS…GQAAR → MPPPPLLSLRRLGGGWSAVT RLVVAAAGARSRGGRGGSRG AGGGGRGGVARRRRLELRAA RSLLGSS in isoform Long.		VSP_002010
	Natural variant	341	1	R → M. Ref.8 Corresponds to variant rs17855906 [ dbSNP | Ensembl ].		VAR_055041
	Natural variant	445	1	R → L. Corresponds to variant rs3733055 [ dbSNP | Ensembl ].		VAR_020021
Experimental info
	Sequence conflict	284	1	G → GLLR in CAA54814. Ref.2
	Sequence conflict	284	1	G → GLLR in CAA53046. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Isoform Short (hIVR8) [UniParc]. Last modified October 1, 1993. Version 1. Checksum: DAA40CF5BEC47D7D	FASTA	457	51,547
	10 20 30 40 50 60 MRPPSPLPAR WLCVLAGALA WALGPAGGQA ARLQEECDYV QMIEVQHKQC LEEAQLENET 70 80 90 100 110 120 IGCSKMWDNL TCWPATPRGQ VVVLACPLIF KLFSSIQGRN VSRSCTDEGW THLEPGPYPI 130 140 150 160 170 180 ACGLDDKAAS LDEQQTMFYG SVKTGYTIGY GLSLATLLVA TAILSLFRKL HCTRNYIHMH 190 200 210 220 230 240 LFISFILRAA AVFIKDLALF DSGESDQCSE GSVGCKAAMV FFQYCVMANF FWLLVEGLYL 250 260 270 280 290 300 YTLLAVSFFS ERKYFWGYIL IGWGVPSTFT MVWTIARIHF EDYGCWDTIN SSLWWIIKGP 310 320 330 340 350 360 ILTSILVNFI LFICIIRILL QKLRPPDIRK SDSSPYSRLA RSTLLLIPLF GVHYIMFAFF 370 380 390 400 410 420 PDNFKPEVKM VFELVVGSFQ GFVVAILYCF LNGEVQAELR RKWRRWHLQG VLGWNPKYRH 430 440 450 PSGGSNGATC STQVSMLTRV SPGARRSSSF QAEVSLV
	Isoform Long (hIVR5) [UniParc]. Checksum: D6E529795785C3AA	FASTA	492	55,009
	10 20 30 40 50 60 MPPPPLLSLR RLGGGWSAVT RLVVAAAGAR SRGGRGGSRG AGGGGRGGVA RRRRLELRAA 70 80 90 100 110 120 RSLLGSSLQE ECDYVQMIEV QHKQCLEEAQ LENETIGCSK MWDNLTCWPA TPRGQVVVLA 130 140 150 160 170 180 CPLIFKLFSS IQGRNVSRSC TDEGWTHLEP GPYPIACGLD DKAASLDEQQ TMFYGSVKTG 190 200 210 220 230 240 YTIGYGLSLA TLLVATAILS LFRKLHCTRN YIHMHLFISF ILRAAAVFIK DLALFDSGES 250 260 270 280 290 300 DQCSEGSVGC KAAMVFFQYC VMANFFWLLV EGLYLYTLLA VSFFSERKYF WGYILIGWGV 310 320 330 340 350 360 PSTFTMVWTI ARIHFEDYGC WDTINSSLWW IIKGPILTSI LVNFILFICI IRILLQKLRP 370 380 390 400 410 420 PDIRKSDSSP YSRLARSTLL LIPLFGVHYI MFAFFPDNFK PEVKMVFELV VGSFQGFVVA 430 440 450 460 470 480 ILYCFLNGEV QAELRRKWRR WHLQGVLGWN PKYRHPSGGS NGATCSTQVS MLTRVSPGAR 490 RSSSFQAEVS LV
	Isoform 3 [UniParc]. Checksum: 271C125CB317C516	FASTA	247	28,164
	10 20 30 40 50 60 MTRQRVWMRW AVRQPWSFSN IVSWLTSSGC WWRASTCTPC LPSPSSLSGS TSGGVPSTFT 70 80 90 100 110 120 MVWTIARIHF EDYGCWDTIN SSLWWIIKGP ILTSILVNFI LFICIIRILL QKLRPPDIRK 130 140 150 160 170 180 SDSSPYSRLA RSTLLLIPLF GVHYIMFAFF PDNFKPEVKM VFELVVGSFQ GFVVAILYCF 190 200 210 220 230 240 LNGEVQAELR RKWRRWHLQG VLGWNPKYRH PSGGSNGATC STQVSMLTRV SPGARRSSSF QAEVSLV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning and functional expression of a human neuroendocrine vasoactive intestinal peptide receptor." Sreedharan S.P., Patel D.R., Huang J.-X., Goetzl E.J. Biochem. Biophys. Res. Commun. 193:546-553(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM SHORT). Tissue: Intestine.
[2]	"Human intestinal VIP receptor: cloning and functional expression of two cDNA encoding proteins with different N-terminal domains." Couvineau A., Rouyer-Fessard C., Darmoul D., Maoret J.J., Carrero I., Ogier-Denis E., Laburthe M. Biochem. Biophys. Res. Commun. 200:769-776(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS SHORT AND LONG), ALTERNATIVE SPLICING. Tissue: Intestine.
[3]	"Genome-wide discovery and analysis of human seven transmembrane helix receptor genes." Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S., Tsutsumi S., Aburatani H., Asai K., Akiyama Y. Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[4]	Martin A.L., Kaighin V.A., Aronstam R.S. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM SHORT). Tissue: Lung.
[5]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS SHORT AND 3). Tissue: Cerebellum and Lung.
[6]	"The DNA sequence, annotation and analysis of human chromosome 3." Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J. , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A. Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[7]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[8]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM SHORT), VARIANT MET-341.
[9]	"Molecular cloning and functional characterization of a human liver vasoactive intestinal peptide receptor." Gagnon A.W., Aiyar N., Elshourbagy N.A. Cell. Signal. 6:321-333(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 33-457. Tissue: Liver.
[10]	"Highly conserved aspartate 68, tryptophan 73 and glycine 109 in the N-terminal extracellular domain of the human VIP receptor are essential for its ability to bind VIP." Couvineau A., Gaudin P., Maoret J.J., Rouyer-Fessard C., Nicole P., Laburthe M. Biochem. Biophys. Res. Commun. 206:246-252(1995) [PubMed] [Europe PMC] [Abstract] Cited for: INTERACTION WITH VIP.
[11]	"Predominant expression of type II vasoactive intestinal peptide receptors by human T lymphoblastoma cells: transduction of both Ca2+ and cyclic AMP signals." Xia M., Sreedharan S.P., Goetzl E.J. J. Clin. Immunol. 16:21-30(1996) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION, TISSUE SPECIFICITY.
[12]	"Importance of conserved cysteines in the extracellular loops of human PACAP/VIP1 receptor for ligand binding and stimulation of cAMP production." Knudsen S.M., Tams J.W., Wulff B.S., Fahrenkrug J. Ann. N. Y. Acad. Sci. 865:259-265(1998) [PubMed] [Europe PMC] [Abstract] Cited for: DISULFIDE BOND.
[13]	"Dual, HLA-B27 subtype-dependent conformation of a self-peptide." Hulsmeyer M., Fiorillo M.T., Bettosini F., Sorrentino R., Saenger W., Ziegler A., Uchanska-Ziegler B. J. Exp. Med. 199:271-281(2004) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.47 ANGSTROMS) OF 400-408 IN COMPLEX WITH MHC.
[14]	"Citrullination-dependent differential presentation of a self-peptide by HLA-B27 subtypes." Beltrami A., Rossmann M., Fiorillo M.T., Paladini F., Sorrentino R., Saenger W., Kumar P., Ziegler A., Uchanska-Ziegler B. J. Biol. Chem. 283:27189-27199(2008) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.86 ANGSTROMS) OF 400-408 IN COMPLEX WITH MHC.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

L13288 mRNA. Translation: AAA36805.1.
U11087 , U11079, U11080, U11081, U11083, U11084, U11085, U11086 Genomic DNA. Translation: AAB60362.1.
X75299 mRNA. Translation: CAA53046.1.
X77777 mRNA. Translation: CAA54814.1.
AB065669 Genomic DNA. Translation: BAC05895.1.
EF577396 mRNA. Translation: ABQ52416.1.
AK314334 mRNA. Translation: BAG36980.1.
AK293548 mRNA. Translation: BAG57026.1.
AC092047 Genomic DNA. No translation available.
CH471055 Genomic DNA. Translation: EAW64649.1.
BC064424 mRNA. Translation: AAH64424.1.
L20295 mRNA. Translation: AAA36802.1.

IPI

IPI00027680.
IPI00218266.

PIR

JC2194.
JC2195.

RefSeq

NP_001238812.1. NM_001251883.1.
NP_004615.2. NM_004624.3.

UniGene

Hs.348500.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1OF2	X-ray	2.20	C	400-408	[»]
1OGT	X-ray	1.47	C	400-408	[»]
3B3I	X-ray	1.86	C	400-408	[»]

ProteinModelPortal

P32241.

ModBase

Search...

Protein-protein interaction databases

IntAct

P32241. 1 interaction.

MINT

MINT-1217405.

STRING

9606.ENSP00000327246.

Protein family/group databases

GPCRDB

Search...

PTM databases

PhosphoSite

P32241.

Polymorphism databases

DMDM

418253.

Proteomic databases

PaxDb

P32241.

PRIDE

P32241.

Protocols and materials databases

DNASU

7433.

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

Ensembl

ENST00000325123; ENSP00000327246; ENSG00000114812.
ENST00000438259; ENSP00000415371; ENSG00000114812.

GeneID

7433.

KEGG

hsa:7433.

UCSC

uc003clf.2. human.

Organism-specific databases

CTD

7433.

GeneCards

GC03P042520.

HGNC

HGNC:12694. VIPR1.

HPA

HPA026777.

MIM

192321. gene.

neXtProt

NX_P32241.

PharmGKB

PA37313.

GenAtlas

Search...

Phylogenomic databases

eggNOG

NOG293423.

HOGENOM

HOG000008249.

HOVERGEN

HBG008318.

InParanoid

P32241.

KO

K04589.

OMA

REECIYL.

PhylomeDB

P32241.

Enzyme and pathway databases

Reactome

REACT_111102. Signal Transduction.

Gene expression databases

ArrayExpress

P32241.

Bgee

P32241.

CleanEx

HS_VIPR1.

Genevestigator

P32241.

GermOnline

ENSG00000114812. Homo sapiens.

Family and domain databases

InterPro

IPR017981. GPCR_2-like.
IPR001879. GPCR_2_extracellular_dom.
IPR000832. GPCR_2_secretin-like.
IPR017983. GPCR_2_secretin-like_CS.
IPR001571. GPCR_2_VIP_rcpt.
IPR001771. GPCR_2_VIP_rcpt_1.
[Graphical view]

Pfam

PF00002. 7tm_2. 1 hit.
PF02793. HRM. 1 hit.
[Graphical view]

PRINTS

PR00249. GPCRSECRETIN.
PR00491. VASOACTVEIPR.
PR01154. VIP1RECEPTOR.

SMART

SM00008. HormR. 1 hit.
[Graphical view]

PROSITE

PS00649. G_PROTEIN_RECEP_F2_1. 1 hit.
PS00650. G_PROTEIN_RECEP_F2_2. 1 hit.
PS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

BindingDB

P32241.

ChEMBL

CHEMBL5144.

ChiTaRS

VIPR1. human.

EvolutionaryTrace

P32241.

GenomeRNAi

7433.

NextBio

29114.

SOURCE

Search...

Entry information

Entry name

VIPR1_HUMAN

Accession

Primary (citable) accession number: P32241
Secondary accession number(s): A5JUT9 , B4DEB5, Q15871, Q6P2M6

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1993
Last sequence update:	October 1, 1993
Last modified:	May 1, 2013
This is version 127 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.