P32157 (YIIM_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein YiiM

Gene names

Name:	yiiM
Ordered Locus Names:	b3910, JW5559

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	224 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subunit structure	Monomer. Ref.4
Sequence similarities	Contains 1 MOSC domain.
Sequence caution	The sequence AAB03043.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Ontologies

Keywords
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	metabolic process Inferred from electronic annotation. Source: GOC response to toxin Inferred from mutant phenotype PubMed 18312271. Source: EcoCyc
Molecular_function	catalytic activity Inferred from electronic annotation. Source: InterPro molybdenum ion binding Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 224

224

Protein YiiM

PRO_0000169688

Regions

Domain

26 – 163

138

MOSC

Secondary structure

1

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

224

Helix Strand Turn

Details...

Beta strand

6 – 9

4

Beta strand

26 – 28

3

Beta strand

30 – 35

6

Helix

52 – 55

4

Beta strand

56 – 61

6

Helix

63 – 71

9

Helix

73 – 78

6

Turn

81 – 84

4

Beta strand

87 – 92

6

Turn

95 – 97

3

Beta strand

103 – 106

4

Beta strand

109 – 116

8

Helix

122 – 126

5

Helix

132 – 139

8

Beta strand

144 – 150

7

Beta strand

152 – 155

4

Beta strand

160 – 164

5

Helix

171 – 179

9

Helix

185 – 192

8

Helix

199 – 211

13

Helix

218 – 222

5

Sequences

	Sequence		Length	Mass (Da)
	P32157 [UniParc]. Last modified July 11, 2001. Version 2. Checksum: D9691FB9357F0E38	FASTA	224	25,343
	10 20 30 40 50 60 MRYPVDVYTG KIQAYPEGKP SAIAKIQVDG ELMLTELGLE GDEQAEKKVH GGPDRALCHY 70 80 90 100 110 120 PREHYLYWAR EFPEQAELFV APAFGENLST DGLTESNVYM GDIFRWGEAL IQVSQPRSPC 130 140 150 160 170 180 YKLNYHFDIS DIAQLMQNTG KVGWLYSVIA PGKVSADAPL ELVSRVSDVT VQEAAAIAWH 190 200 210 220 MPFDDDQYHR LLSAAGLSKS WTRTMQKRRL SGKIEDFSRR LWGK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Analysis of the Escherichia coli genome. III. DNA sequence of the region from 87.2 to 89.2 minutes." Plunkett G. III, Burland V., Daniels D.L., Blattner F.R. Nucleic Acids Res. 21:3391-3398(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]	"Structural analysis of a set of proteins resulting from a bacterial genomics project." Badger J., Sauder J.M., Adams J.M., Antonysamy S., Bain K., Bergseid M.G., Buchanan S.G., Buchanan M.D., Batiyenko Y., Christopher J.A., Emtage S., Eroshkina A., Feil I., Furlong E.B., Gajiwala K.S., Gao X., He D., Hendle J. , Huber A., Hoda K., Kearins P., Kissinger C., Laubert B., Lewis H.A., Lin J., Loomis K., Lorimer D., Louie G., Maletic M., Marsh C.D., Miller I., Molinari J., Muller-Dieckmann H.J., Newman J.M., Noland B.W., Pagarigan B., Park F., Peat T.S., Post K.W., Radojicic S., Ramos A., Romero R., Rutter M.E., Sanderson W.E., Schwinn K.D., Tresser J., Winhoven J., Wright T.A., Wu L., Xu J., Harris T.J.R. Proteins 60:787-796(2005) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.33 ANGSTROMS), SUBUNIT.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

L19201 Genomic DNA. Translation: AAB03043.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76892.2.
AP009048 Genomic DNA. Translation: BAE77399.1.

PIR

S40854.

RefSeq

NP_418346.2. NC_000913.2.
YP_491540.1. NC_007779.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1O65	X-ray	2.33	A/B/C	1-224	[»]
1O67	X-ray	2.54	A/B/C	1-224	[»]

ProteinModelPortal

P32157.

SMR

P32157. Positions 1-223.

ModBase

Search...

Protein-protein interaction databases

DIP

DIP-12512N.

STRING

511145.b3910.

Proteomic databases

PaxDb

P32157.

PRIDE

P32157.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

AAC76892; AAC76892; b3910.
BAE77399; BAE77399; BAE77399.

GeneID

12933649.
948406.

KEGG

ecj:Y75_p3276.
eco:b3910.

PATRIC

32123333. VBIEscCol129921_4027.

Organism-specific databases

EchoBASE

EB1816.

EcoGene

EG11870. yiiM.

Phylogenomic databases

eggNOG

COG2258.

HOGENOM

HOG000051122.

OMA

FDEEQYR.

ProtClustDB

PRK11536.

Enzyme and pathway databases

BioCyc

EcoCyc:EG11870-MONOMER.
ECOL316407:JW5559-MONOMER.

Gene expression databases

Genevestigator

P32157.

Family and domain databases

Gene3D

2.40.33.20. 1 hit.

InterPro

IPR005163. 3-alpha_domain.
IPR005302. MoCF_Sase_C.
IPR015808. MoCF_Sase_C-like.
IPR011037. Pyrv_Knase-like_insert_dom.
[Graphical view]

Pfam

PF03475. 3-alpha. 1 hit.
PF03473. MOSC. 1 hit.
[Graphical view]

SUPFAM

SSF50800. PK_B_barrel_like. 1 hit.

PROSITE

PS51340. MOSC. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

P32157.

Entry information

Entry name

YIIM_ECOLI

Accession

Primary (citable) accession number: P32157
Secondary accession number(s): Q2M8K7

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1993
Last sequence update:	July 11, 2001
Last modified:	May 1, 2013
This is version 99 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program