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Protein

Putative frv operon regulatory protein

Gene

frvR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Could be involved in the regulation of the transcription of the FRV operon.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi20 – 39H-T-H motifBy similarityAdd BLAST20

GO - Molecular functioni

GO - Biological processi

  • regulation of transcription, DNA-templated Source: UniProtKB-KW
  • transcription, DNA-templated Source: EcoCyc

Keywordsi

Molecular functionDNA-binding, Kinase, Transferase
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciEcoCyc:EG11861-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Putative frv operon regulatory protein
Including the following 1 domains:
Putative phosphotransferase EIIA component (EC:2.7.1.-)
Alternative name(s):
Putative PTS system EIIA component
Gene namesi
Name:frvR
Synonyms:yiiH
Ordered Locus Names:b3897, JW3868
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11861 frvR

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000873491 – 582Putative frv operon regulatory proteinAdd BLAST582

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei505Phosphohistidine; by HPrBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP32152
PRIDEiP32152

PTM databases

iPTMnetiP32152

Interactioni

Protein-protein interaction databases

BioGridi4263326, 6 interactors
IntActiP32152, 1 interactor
STRINGi316385.ECDH10B_4087

Structurei

3D structure databases

ProteinModelPortaliP32152
SMRiP32152
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini443 – 582PTS EIIA type-2PROSITE-ProRule annotationAdd BLAST140

Domaini

The PTS EIIA type-2 domain may serve a regulatory function, through its phosphorylation activity.

Phylogenomic databases

eggNOGiENOG4106C3V Bacteria
COG1762 LUCA
COG3711 LUCA
HOGENOMiHOG000009657
InParanoidiP32152
KOiK18531
OMAiEIINHVL
PhylomeDBiP32152

Family and domain databases

Gene3Di1.10.10.10, 1 hit
3.40.930.10, 1 hit
InterProiView protein in InterPro
IPR013196 HTH_11
IPR016152 PTrfase/Anion_transptr
IPR002178 PTS_EIIA_type-2_dom
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF08279 HTH_11, 1 hit
PF00359 PTS_EIIA_2, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
SSF55804 SSF55804, 1 hit
PROSITEiView protein in PROSITE
PS51094 PTS_EIIA_TYPE_2, 1 hit

Sequencei

Sequence statusi: Complete.

P32152-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLNERQLKIV DLLEQQPRTP GELAQQTGVS GRTILRDIDY LNFTLNGKAR
60 70 80 90 100
IFASGSAGYQ LEIFERRSFF QLLQKHDNDD RLLALLLLNT FTPRAQLASA
110 120 130 140 150
LNLPETWVAE RLPRLKQRYE RTCCLASRPG LGHFIDETEE KRVILLANLL
160 170 180 190 200
RKDPFLIPLA GITRDNLQHL STACDNQHRW PLMQGDYLSS LILAIYALRN
210 220 230 240 250
QLTDEWPQYP GDEIKQIVEH SGLFLGDNAV RTLTGLIEKQ HQQAQVISAD
260 270 280 290 300
NVQGLLQRVP GIASLNIIDA QLVENITGHL LRCLAAPVWI AEHRQSSMNN
310 320 330 340 350
LKAAWPAAFD MSLHFITLLR EQLDIPLFDS DLIGLYFACA LERHQNERQP
360 370 380 390 400
IILLSDQNAI ATINQLAIER DVLNCRVIIA RSLSELVAIR EEIEPLLIIN
410 420 430 440 450
NSHYLLDDAV NNYITVKNII TAAGIEQIKH FLATAFIRQQ PERFFSAPGS
460 470 480 490 500
FHYSNVRGES WQHITRQICA QLVAQHHITA DEAQRIIARE GEGENLIVNR
510 520 530 540 550
LAIPHCWSEQ ERRFRGFFIT LAQPVEVNNE VINHVLIACA AADARHELKI
560 570 580
FSYLASILCQ HPAEIIAGLT GYEAFMELLH KG
Length:582
Mass (Da):66,000
Last modified:October 1, 1993 - v1
Checksum:i96F37F10C58C2A10
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L19201 Genomic DNA Translation: AAB03030.1
U00096 Genomic DNA Translation: AAC76879.1
AP009048 Genomic DNA Translation: BAE77412.1
PIRiS40841
RefSeqiNP_418333.1, NC_000913.3
WP_000931299.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76879; AAC76879; b3897
BAE77412; BAE77412; BAE77412
GeneIDi948389
KEGGiecj:JW3868
eco:b3897
PATRICifig|1411691.4.peg.2810

Entry informationi

Entry nameiFRVR_ECOLI
AccessioniPrimary (citable) accession number: P32152
Secondary accession number(s): Q2M8J4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: March 28, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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