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Protein

Sulfofructose kinase

Gene

yihV

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Phosphorylates 6-deoxy-6-sulfo-D-fructose (SF) to 6-deoxy-6-sulfo-D-fructose 1-phosphate (SFP).UniRule annotation1 Publication

Catalytic activityi

ATP + 6-deoxy-6-sulfo-D-fructose = ADP + 6-deoxy-6-sulfo-D-fructose 1-phosphate.UniRule annotation1 Publication

GO - Molecular functioni

  • 6-deoxy-6-sulfofructose kinase activity Source: EcoCyc
  • ATP binding Source: UniProtKB-KW
  • ribokinase activity Source: InterPro

GO - Biological processi

  • 6-sulfoquinovose(1-) catabolic process Source: EcoCyc
  • carbohydrate phosphorylation Source: EcoCyc
  • D-ribose metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciEcoCyc:EG11848-MONOMER.
ECOL316407:JW5568-MONOMER.
MetaCyc:EG11848-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Sulfofructose kinaseUniRule annotation (EC:2.7.1.184UniRule annotation)
Short name:
SF kinaseUniRule annotation
Gene namesi
Name:yihV
Ordered Locus Names:b3883, JW5568
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11848. yihV.

Pathology & Biotechi

Disruption phenotypei

Mutant fails to grow on sulfoquinovose as a sole carbon source.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000801491 – 298Sulfofructose kinaseAdd BLAST298

Proteomic databases

PaxDbiP32143.
PRIDEiP32143.

Expressioni

Inductioni

Induced during growth with sulfoquinovose.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4260966. 8 interactors.
STRINGi511145.b3883.

Structurei

3D structure databases

ProteinModelPortaliP32143.
SMRiP32143.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the carbohydrate kinase PfkB family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108MGF. Bacteria.
ENOG410YU6C. LUCA.
HOGENOMiHOG000235950.
InParanoidiP32143.
KOiK18478.
OMAiENKTMDD.
PhylomeDBiP32143.

Family and domain databases

Gene3Di3.40.1190.20. 1 hit.
HAMAPiMF_00999. SF_kinase. 1 hit.
InterProiIPR002173. Carboh/pur_kinase_PfkB_CS.
IPR011611. PfkB_dom.
IPR002139. Ribo/fructo_kinase.
IPR029056. Ribokinase-like.
IPR030877. SF_kinase.
[Graphical view]
PfamiPF00294. PfkB. 1 hit.
[Graphical view]
PRINTSiPR00990. RIBOKINASE.
SUPFAMiSSF53613. SSF53613. 1 hit.
PROSITEiPS00584. PFKB_KINASES_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P32143-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIRVACVGIT VMDRIYYVEG LPTESGKYVA RNYTEVGGGP AATAAVAAAR
60 70 80 90 100
LGAQVDFIGR VGDDDTGNSL LAELESWGVN TRYTKRYNQA KSSQSAIMVD
110 120 130 140 150
TKGERIIINY PSPDLLPDAE WLEEIDFSQW DVVLADVRWH DGAKKAFTLA
160 170 180 190 200
RQAGVMTVLD GDITPQDISE LVALSDHAAF SEPGLARLTG VKEMASALKQ
210 220 230 240 250
AQTLTNGHVY VTQGSAGCDW LENGGRQHQP AFKVDVVDTT GAGDVFHGAL
260 270 280 290
AVALATSGDL AESVRFASGV AALKCTRPGG RAGIPDCDQT RSFLSLFV
Length:298
Mass (Da):31,728
Last modified:December 15, 1998 - v2
Checksum:i24D347B04542909E
GO

Sequence cautioni

The sequence AAB03016 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L19201 Genomic DNA. Translation: AAB03016.1. Different initiation.
U00096 Genomic DNA. Translation: AAD13445.2.
AP009048 Genomic DNA. Translation: BAE77426.1.
PIRiS40827.
RefSeqiNP_418319.2. NC_000913.3.
WP_000621656.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAD13445; AAD13445; b3883.
BAE77426; BAE77426; BAE77426.
GeneIDi948382.
KEGGiecj:JW5568.
eco:b3883.
PATRICi32123269. VBIEscCol129921_3995.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L19201 Genomic DNA. Translation: AAB03016.1. Different initiation.
U00096 Genomic DNA. Translation: AAD13445.2.
AP009048 Genomic DNA. Translation: BAE77426.1.
PIRiS40827.
RefSeqiNP_418319.2. NC_000913.3.
WP_000621656.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP32143.
SMRiP32143.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260966. 8 interactors.
STRINGi511145.b3883.

Proteomic databases

PaxDbiP32143.
PRIDEiP32143.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD13445; AAD13445; b3883.
BAE77426; BAE77426; BAE77426.
GeneIDi948382.
KEGGiecj:JW5568.
eco:b3883.
PATRICi32123269. VBIEscCol129921_3995.

Organism-specific databases

EchoBASEiEB1794.
EcoGeneiEG11848. yihV.

Phylogenomic databases

eggNOGiENOG4108MGF. Bacteria.
ENOG410YU6C. LUCA.
HOGENOMiHOG000235950.
InParanoidiP32143.
KOiK18478.
OMAiENKTMDD.
PhylomeDBiP32143.

Enzyme and pathway databases

BioCyciEcoCyc:EG11848-MONOMER.
ECOL316407:JW5568-MONOMER.
MetaCyc:EG11848-MONOMER.

Miscellaneous databases

PROiP32143.

Family and domain databases

Gene3Di3.40.1190.20. 1 hit.
HAMAPiMF_00999. SF_kinase. 1 hit.
InterProiIPR002173. Carboh/pur_kinase_PfkB_CS.
IPR011611. PfkB_dom.
IPR002139. Ribo/fructo_kinase.
IPR029056. Ribokinase-like.
IPR030877. SF_kinase.
[Graphical view]
PfamiPF00294. PfkB. 1 hit.
[Graphical view]
PRINTSiPR00990. RIBOKINASE.
SUPFAMiSSF53613. SSF53613. 1 hit.
PROSITEiPS00584. PFKB_KINASES_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSQUV_ECOLI
AccessioniPrimary (citable) accession number: P32143
Secondary accession number(s): Q2M8I0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: December 15, 1998
Last modified: November 2, 2016
This is version 117 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.