Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Sulfofructosephosphate aldolase

Gene

yihT

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Cleaves 6-deoxy-6-sulfo-D-fructose 1-phosphate (SFP) to form dihydroxyacetone phosphate (DHAP) and 3-sulfolactaldehyde (SLA).UniRule annotation1 Publication

Catalytic activityi

6-deoxy-6-sulfo-D-fructose 1-phosphate = glycerone phosphate + 2-hydroxy-3-oxopropane-1-sulfonate.UniRule annotation1 Publication

GO - Molecular functioni

  • 6-deoxy-6-sulfofructose-1-phosphate aldolase activity Source: EcoCyc

GO - Biological processi

  • 6-sulfoquinovose(1-) catabolic process Source: EcoCyc
  • 6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde Source: EcoCyc

Keywordsi

Molecular functionLyase

Enzyme and pathway databases

BioCyciEcoCyc:EG11846-MONOMER
MetaCyc:EG11846-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Sulfofructosephosphate aldolaseUniRule annotation (EC:4.1.2.57UniRule annotation)
Short name:
SFP aldolaseUniRule annotation
Gene namesi
Name:yihT
Ordered Locus Names:b3881, JW3852
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11846 yihT

Pathology & Biotechi

Disruption phenotypei

Mutant fails to grow on sulfoquinovose as a sole carbon source.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002039691 – 292Sulfofructosephosphate aldolaseAdd BLAST292

Proteomic databases

PaxDbiP32141
PRIDEiP32141

Expressioni

Inductioni

Induced during growth with sulfoquinovose.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi42626398 interactors.
IntActiP32141 5 interactors.
STRINGi316385.ECDH10B_4071

Structurei

3D structure databases

ProteinModelPortaliP32141
SMRiP32141
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldolase LacD family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D2M Bacteria
COG3684 LUCA
HOGENOMiHOG000244296
InParanoidiP32141
KOiK01671
OMAiKDITRPS
PhylomeDBiP32141

Family and domain databases

Gene3Di3.20.20.701 hit
HAMAPiMF_01912 SFP_aldolase, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR002915 DeoC/FbaB/lacD_aldolase
IPR017291 SFP_aldolase_YihT
PfamiView protein in Pfam
PF01791 DeoC, 1 hit
PIRSFiPIRSF037840 Aldolase_YihT, 1 hit
SMARTiView protein in SMART
SM01133 DeoC, 1 hit

Sequencei

Sequence statusi: Complete.

P32141-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKYTINDIT RASGGFAMLA VDQREAMRMM FAAAGAPAPV ADSVLTDFKV
60 70 80 90 100
NAAKALSPYA SAILVDQQFC YRQVVEQNAI AKSCAMIVAA DEFIPGNGIP
110 120 130 140 150
VDSVVIDRKI NPLQIKQDGG KALKLLVLWR SDEDAQQRLD MVKEFNELCH
160 170 180 190 200
SHGLVSIIEP VVRPPRRGDK FDREQAIIDA AKELGDSGAD LYKVEMPLYG
210 220 230 240 250
KGPQQELLCA SQRLNDHINM PWVILSSGVD EKLFPRAVRV AMTAGASGFL
260 270 280 290
AGRAVWASVV GLPDNELMLR DVCAPKLQQL GDIVDEMMAK RR
Length:292
Mass (Da):31,983
Last modified:October 1, 1993 - v1
Checksum:i4A54012E39FF447F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L19201 Genomic DNA Translation: AAB03014.1
U00096 Genomic DNA Translation: AAD13443.1
AP009048 Genomic DNA Translation: BAE77428.1
PIRiS40825
RefSeqiNP_418317.1, NC_000913.3
WP_001046453.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAD13443; AAD13443; b3881
BAE77428; BAE77428; BAE77428
GeneIDi948373
KEGGiecj:JW3852
eco:b3881
PATRICifig|1411691.4.peg.2830

Similar proteinsi

Entry informationi

Entry nameiSQUT_ECOLI
AccessioniPrimary (citable) accession number: P32141
Secondary accession number(s): Q2M8H8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: March 28, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome