##gff-version 3 P32121 UniProtKB Chain 1 409 . . . ID=PRO_0000205199;Note=Beta-arrestin-2 P32121 UniProtKB Region 240 409 . . . Note=Interaction with TRAF6;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16378096;Dbxref=PMID:16378096 P32121 UniProtKB Region 363 409 . . . Note=Interaction with AP2B1 P32121 UniProtKB Motif 385 395 . . . Note=[DE]-X(1%2C2)-F-X-X-[FL]-X-X-X-R motif P32121 UniProtKB Modified residue 48 48 . . . Note=Phosphotyrosine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q91YI4 P32121 UniProtKB Modified residue 176 176 . . . Note=Hydroxyproline%3B by PHD2;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:21255264;Dbxref=PMID:21255264 P32121 UniProtKB Modified residue 181 181 . . . Note=Hydroxyproline%3B by PHD2;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:21255264;Dbxref=PMID:21255264 P32121 UniProtKB Modified residue 360 360 . . . Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P29067 P32121 UniProtKB Modified residue 382 382 . . . Note=Phosphothreonine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11877451;Dbxref=PMID:11877451 P32121 UniProtKB Alternative sequence 39 53 . . . ID=VSP_008194;Note=In isoform 3 and isoform 5. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 P32121 UniProtKB Alternative sequence 119 119 . . . ID=VSP_044697;Note=In isoform 4. T->TVRMPLPSEGQGAGAGTVSGVG;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 P32121 UniProtKB Alternative sequence 360 360 . . . ID=VSP_008195;Note=In isoform 2 and isoform 3. S->SAPTPTPPLPVPP;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|Ref.3;Dbxref=PMID:14702039 P32121 UniProtKB Mutagenesis 11 11 . . . Note=Abolishes interaction with CHUK%3B when associated with A-12%3B A-230 and A-231. K->A P32121 UniProtKB Mutagenesis 12 12 . . . Note=Abolishes interaction with CHUK%3B when associated with A-11%3B A-230 and A-231. K->A P32121 UniProtKB Mutagenesis 54 54 . . . Note=Inhibits internalization of CXCR4%3B no effect on interaction with CXCR4. V->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10644702;Dbxref=PMID:10644702 P32121 UniProtKB Mutagenesis 230 230 . . . Note=Abolishes interaction with CHUK%3B when associated with A-11%3B A-12 and A-231. K->A P32121 UniProtKB Mutagenesis 231 231 . . . Note=Abolishes interaction with CHUK%3B when associated with A-11%3B A-12 and A-230. K->A P32121 UniProtKB Mutagenesis 360 360 . . . Note=Reduces interaction with CHUK%3B when associated with A-382. S->A%2CD P32121 UniProtKB Mutagenesis 382 382 . . . Note=Reduces interaction with CHUK%3B when associated with A-360. T->A%2CD;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11877451;Dbxref=PMID:11877451 P32121 UniProtKB Mutagenesis 382 382 . . . Note=Loss of phosphorylation. T->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11877451;Dbxref=PMID:11877451 P32121 UniProtKB Sequence conflict 13 13 . . . Note=S->P;Ontology_term=ECO:0000305;evidence=ECO:0000305 P32121 UniProtKB Sequence conflict 189 189 . . . Note=R->P;Ontology_term=ECO:0000305;evidence=ECO:0000305 P32121 UniProtKB Sequence conflict 190 190 . . . Note=H->R;Ontology_term=ECO:0000305;evidence=ECO:0000305 P32121 UniProtKB Sequence conflict 192 192 . . . Note=L->P;Ontology_term=ECO:0000305;evidence=ECO:0000305 P32121 UniProtKB Sequence conflict 366 366 . . . Note=D->G;Ontology_term=ECO:0000305;evidence=ECO:0000305