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Protein

Putative colanic acid biosynthesis glycosyl transferase WcaI

Gene

wcaI

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Pathwayi: slime polysaccharide biosynthesis

This protein is involved in the pathway slime polysaccharide biosynthesis, which is part of Slime biogenesis.
View all proteins of this organism that are known to be involved in the pathway slime polysaccharide biosynthesis and in Slime biogenesis.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Lipopolysaccharide biosynthesis

Enzyme and pathway databases

BioCyciEcoCyc:EG11790-MONOMER.
ECOL316407:JW2035-MONOMER.
UniPathwayiUPA00936.

Protein family/group databases

CAZyiGT4. Glycosyltransferase Family 4.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative colanic acid biosynthesis glycosyl transferase WcaI
Gene namesi
Name:wcaI
Synonyms:yefD
Ordered Locus Names:b2050, JW2035
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11790. wcaI.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000659571 – 407Putative colanic acid biosynthesis glycosyl transferase WcaIAdd BLAST407

Proteomic databases

PaxDbiP32057.
PRIDEiP32057.

Interactioni

Protein-protein interaction databases

BioGridi4263310. 342 interactors.
DIPiDIP-11124N.
IntActiP32057. 1 interactor.
MINTiMINT-1309672.
STRINGi511145.b2050.

Structurei

3D structure databases

ProteinModelPortaliP32057.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4106CD9. Bacteria.
COG0438. LUCA.
HOGENOMiHOG000079950.
InParanoidiP32057.
KOiK03208.
OMAiWMAREGH.
PhylomeDBiP32057.

Family and domain databases

InterProiIPR023910. Colanic_acid_synth_WcaI.
IPR001296. Glyco_trans_1.
IPR028098. Glyco_trans_4-like_N.
[Graphical view]
PfamiPF13579. Glyco_trans_4_4. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR04007. wcaI. 1 hit.

Sequencei

Sequence statusi: Complete.

P32057-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKILVYGINY SPELTGIGKY TGEMVEWLAA QGHEVRVITA PPYYPQWQVG
60 70 80 90 100
ENYSAWRYKR EEGAATVWRC PLYVPKQPST LKRLLHLGSF AVSSFFPLMA
110 120 130 140 150
QRRWKPDRII GVVPTLFCAP GMRLLAKLSG ARTVLHIQDY EVDAMLGLGL
160 170 180 190 200
AGKGKGGKVA QLATAFERSG LHNVDNVSTI SRSMMNKAIE KGVAAENVIF
210 220 230 240 250
FPNWSEIARF QHVADADVDA LRNQLDLPDN KKIILYSGNI GEKQGLENVI
260 270 280 290 300
EAADRLRDEP LIFAIVGQGG GKARLEKMAQ QRGLRNMQFF PLQSYDALPA
310 320 330 340 350
LLKMGDCHLV VQKRGAADAV LPSKLTNILA VGGNAVITAE AYTELGQLCE
360 370 380 390 400
TFPGIAVCVE PESVEALVAG IRQALLLPKH NTVAREYAER TLDKENVLRQ

FINDIRG
Length:407
Mass (Da):44,914
Last modified:October 1, 1993 - v1
Checksum:i6EC5AA8D6DFB4962
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U38473 Genomic DNA. Translation: AAC77845.1.
U00096 Genomic DNA. Translation: AAC75111.1.
AP009048 Genomic DNA. Translation: BAA15906.1.
PIRiF55239.
RefSeqiNP_416554.1. NC_000913.3.
WP_000699693.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75111; AAC75111; b2050.
BAA15906; BAA15906; BAA15906.
GeneIDi946588.
KEGGiecj:JW2035.
eco:b2050.
PATRICi32119433. VBIEscCol129921_2127.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U38473 Genomic DNA. Translation: AAC77845.1.
U00096 Genomic DNA. Translation: AAC75111.1.
AP009048 Genomic DNA. Translation: BAA15906.1.
PIRiF55239.
RefSeqiNP_416554.1. NC_000913.3.
WP_000699693.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP32057.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263310. 342 interactors.
DIPiDIP-11124N.
IntActiP32057. 1 interactor.
MINTiMINT-1309672.
STRINGi511145.b2050.

Protein family/group databases

CAZyiGT4. Glycosyltransferase Family 4.

Proteomic databases

PaxDbiP32057.
PRIDEiP32057.

Protocols and materials databases

DNASUi946588.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75111; AAC75111; b2050.
BAA15906; BAA15906; BAA15906.
GeneIDi946588.
KEGGiecj:JW2035.
eco:b2050.
PATRICi32119433. VBIEscCol129921_2127.

Organism-specific databases

EchoBASEiEB1738.
EcoGeneiEG11790. wcaI.

Phylogenomic databases

eggNOGiENOG4106CD9. Bacteria.
COG0438. LUCA.
HOGENOMiHOG000079950.
InParanoidiP32057.
KOiK03208.
OMAiWMAREGH.
PhylomeDBiP32057.

Enzyme and pathway databases

UniPathwayiUPA00936.
BioCyciEcoCyc:EG11790-MONOMER.
ECOL316407:JW2035-MONOMER.

Miscellaneous databases

PROiP32057.

Family and domain databases

InterProiIPR023910. Colanic_acid_synth_WcaI.
IPR001296. Glyco_trans_1.
IPR028098. Glyco_trans_4-like_N.
[Graphical view]
PfamiPF13579. Glyco_trans_4_4. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR04007. wcaI. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiWCAI_ECOLI
AccessioniPrimary (citable) accession number: P32057
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: November 2, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.