P32003 (CYSE_BUCAP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Serine acetyltransferase
Short name=SAT
EC=2.3.1.30

Gene names

Name:	cysE
Ordered Locus Names:	BUsg_051

Organism

Buchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP]

Taxonomic identifier

198804 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera › Buchnera aphidicola › Buchnera aphidicola (Schizaphis graminum)

Protein attributes

Sequence length	261 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acetyl-CoA + L-serine = CoA + O-acetyl-L-serine.
Pathway	Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 1/2.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the transferase hexapeptide repeat family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Cysteine biosynthesis
Cellular component	Cytoplasm
Domain	Repeat
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	cysteine biosynthetic process from serine Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	serine O-acetyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 261	261	Serine acetyltransferase		PRO_0000068667

Sequences

	Sequence		Length	Mass (Da)
	P32003 [UniParc]. Last modified July 1, 1993. Version 1. Checksum: DC02685464A25944	FASTA	261	28,914
	10 20 30 40 50 60 MCSLEELELW NMIKHKAQKI LKKEPILSNF YQKSILNHKK LSHSLSCILS DKLSTSMISE 70 80 90 100 110 120 KDIYNIFNKI YANNISIINS VVKDIKAASQ RDPVVKHYLT PLLYLKGFHA LEAYRLSHYL 130 140 150 160 170 180 WNIKRYELSA YLQSRISTVF SVDIHPAASI GSGIMLDHAT GIVIGEGVII ENDVSIFHSV 190 200 210 220 230 240 TLGGTGSNTG KNRHPIIRKN VTIGAGAKIL GNIEVGQGVK VGAGSIVLKN IPPFVTVVGV 250 260 PAKIIKKIKN SNKNLFQKEK K

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence analysis of a DNA fragment from Buchnera aphidicola (an endosymbiont of aphids) containing genes homologous to dnaG, rpoD, cysE, and secB." Lai C.-Y., Baumann P. Gene 119:113-118(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"50 million years of genomic stasis in endosymbiotic bacteria." Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E. Science 296:2376-2379(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Sg.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M90644 Genomic DNA. Translation: AAA73232.1. AE013218 Genomic DNA. Translation: AAM67622.1.
PIR	JC1293.
RefSeq	NP_660411.2. NC_004061.1.
3D structure databases
ProteinModelPortal	P32003.
SMR	P32003. Positions 1-251.
ModBase	Search...
Protein-protein interaction databases
STRING	198804.BUsg051.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAM67622; AAM67622; BUsg_051.
GeneID	1005867.
KEGG	bas:BUsg051.
PATRIC	21246867. VBIBucAph100086_0051.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1045.
KO	K00640.
OMA	YPPPESD.
ProtClustDB	CLSK315065.
Enzyme and pathway databases
BioCyc	BAPH198804:GHMG-56-MONOMER.
UniPathway	UPA00136; UER00199.
Family and domain databases
InterPro	IPR001451. Hexapep_transf. IPR018357. Hexapep_transf_CS. IPR010493. Ser_AcTrfase_N. IPR005881. Ser_O-AcTrfase. IPR011004. Trimer_LpxA-like. [Graphical view]
Pfam	PF00132. Hexapep. 1 hit. PF06426. SATase_N. 1 hit. [Graphical view]
SMART	SM00971. SATase_N. 1 hit. [Graphical view]
SUPFAM	SSF51161. Trimer_LpxA_like. 1 hit.
TIGRFAMs	TIGR01172. cysE. 1 hit.
PROSITE	PS00101. HEXAPEP_TRANSFERASES. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CYSE_BUCAP

Accession

Primary (citable) accession number: P32003

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 1993
Last sequence update:	July 1, 1993
Last modified:	May 29, 2013
This is version 85 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program