P32002 (SECB_BUCAP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein-export protein SecB

Gene names

Name:	secB
Ordered Locus Names:	BUsg_050

Organism

Buchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP]

Taxonomic identifier

198804 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera › Buchnera aphidicola › Buchnera aphidicola (Schizaphis graminum)

Protein attributes

Sequence length	154 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA By similarity. HAMAP-Rule MF_00821
Subunit structure	Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the SecB family.

Ontologies

Keywords
Biological process	Protein transport Translocation Transport
Cellular component	Cytoplasm
Molecular function	Chaperone
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	protein folding Inferred from electronic annotation. Source: HAMAP protein tetramerization Inferred from electronic annotation. Source: InterPro protein transport Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 154	154	Protein-export protein SecB HAMAP-Rule MF_00821		PRO_0000055357

Sequences

	Sequence		Length	Mass (Da)
	P32002 [UniParc]. Last modified July 1, 1993. Version 1. Checksum: B65078561968A954	FASTA	154	18,037
	10 20 30 40 50 60 MSEEKLKKKS FEIQRIYIRD ASFEAPNTPN IFHKKWDPEI KFNLSTVSKK LKPNIFETNL 70 80 90 100 110 120 QVRVIVKSEE NLVFLCDVHQ VGIFFISCLD EQELKHCLGS YCPNILFPYA RTCISSLVSY 130 140 150 GSFPQLNLSP IDFDDIFCKN LKSKRNNFYQ KENI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence analysis of a DNA fragment from Buchnera aphidicola (an endosymbiont of aphids) containing genes homologous to dnaG, rpoD, cysE, and secB." Lai C.-Y., Baumann P. Gene 119:113-118(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"50 million years of genomic stasis in endosymbiotic bacteria." Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E. Science 296:2376-2379(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Sg.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M90644 Genomic DNA. Translation: AAA73231.1. AE013218 Genomic DNA. Translation: AAM67621.1.
PIR	JC1292.
RefSeq	NP_660410.1. NC_004061.1.
3D structure databases
ProteinModelPortal	P32002.
SMR	P32002. Positions 10-142.
ModBase	Search...
Protein-protein interaction databases
STRING	198804.BUsg050.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAM67621; AAM67621; BUsg_050.
GeneID	1005866.
KEGG	bas:BUsg050.
PATRIC	21246865. VBIBucAph100086_0050.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1952.
KO	K03071.
OMA	GFPPLMI.
ProtClustDB	PRK05751.
Enzyme and pathway databases
BioCyc	BAPH198804:GHMG-122-MONOMER.
Family and domain databases
Gene3D	3.10.420.10. 1 hit.
HAMAP	MF_00821. SecB.
InterPro	IPR003708. SecB. [Graphical view]
Pfam	PF02556. SecB. 1 hit. [Graphical view]
PRINTS	PR01594. SECBCHAPRONE.
SUPFAM	SSF54611. SecB. 1 hit.
TIGRFAMs	TIGR00809. secB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SECB_BUCAP

Accession

Primary (citable) accession number: P32002

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 1993
Last sequence update:	July 1, 1993
Last modified:	May 1, 2013
This is version 79 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program