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Reviewed, UniProtKB/Swiss-Prot P31973 (FENR_SYNP2)

Last modified June 16, 2009. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Ferredoxin--NADP reductase
      Short name=FNR
    EC=1.18.1.2
Gene names
Name: petH
Ordered Locus Names: SYNPCC7002_A0853
OrganismSynechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum) [Complete proteome] [HAMAP]
Taxonomic identifier32049 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Synechococcus

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Protein attributes

Sequence length402 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

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General annotation (Comments)

Catalytic activity

2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH.

Cofactor

FAD.

Subcellular location

Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note: May be bound to the thylakoid membrane or anchored to the thylakoid-bound phycobilisomes.

Sequence similarities

Belongs to the ferredoxin--NADP reductase type 1 family.

Contains 1 cpcD-like domain.

Contains 1 FAD-binding FR-type domain.

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 402402Ferredoxin--NADP reductase
PRO_0000167637

Regions

Domain18 – 7457CpcD-like
Domain120 – 245126FAD-binding FR-type
Nucleotide binding179 – 1824FAD
Nucleotide binding200 – 2023FAD
Nucleotide binding218 – 2203FAD
Nucleotide binding292 – 2932NADP By similarity
Nucleotide binding322 – 3232NADP By similarity
Nucleotide binding332 – 3365NADP By similarity
Nucleotide binding361 – 3622NADP By similarity

Sites

Binding site1821NADP By similarity
Binding site2021NADP By similarity
Binding site2061FAD By similarity
Binding site2601FAD By similarity
Binding site2601NADP; via amide nitrogen By similarity
Binding site3321NADP By similarity
Binding site4001NADP By similarity

Secondary structure

1 ...................................................... 402
Helix Strand Turn

Details...

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Sequences

Sequence LengthMass (Da)Tools
P31973-1 [UniParc].

Last modified July 1, 1993. Version 1.
Checksum: 5203060291BAFAE7

FASTA40245,015
        10         20         30         40         50         60 
MYGITSTANS TGNQSYANRL FIYEVVGLGG DGRNENSLVR KSGTTFITVP YARMNQEMQR 

        70         80         90        100        110        120 
ITKLGGKIVS IRPAEDAAQI VSEGQSSAQA SAQSPMASST KIVHPKTTDT SVPVNIYRPK 

       130        140        150        160        170        180 
TPFLGKCIEN YELVDEGGSG TVRHVTFDIS EGDLRYLEGQ SIGIIPPGED KNGKPHKLRL 

       190        200        210        220        230        240 
YSIASTRHGD MEDNKTVSLC VRQLEYQDPE SGETVYGVCS TYLCNLPVGT DDVKITGPVG 

       250        260        270        280        290        300 
KEMLLPDDED ATVVMLATGT GIAPFRAFLW RMFKEQHEDY KFKGKAWLIF GVPYTANILY 

       310        320        330        340        350        360 
KDDFEKMAAE NPDNFRLTYA ISREQKTADG GKVYVQSRVS EYADELFEMI QKPNTHVYMC 

       370        380        390        400 
GLKGMQPPID ETFTAEAEKR GLNWEEMRRS MKKEHRWHVE VY

« Hide

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References

« Hide 'large scale' references
[1]"Molecular characterization of ferredoxin-NADP+ oxidoreductase in cyanobacteria: cloning and sequence of the petH gene of Synechococcus sp. PCC 7002 and studies on the gene product."
Schluchter W.M., Bryant D.A.
Biochemistry 31:3092-3102(1992) [PubMed: 1554697] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE, CHARACTERIZATION.
[2]"Complete sequence of Synechococcus sp. PCC 7002."
Li T., Zhao J., Zhao C., Liu Z., Zhao F., Marquardt J., Nomura C.T., Persson S., Detter J.C., Richardson P.M., Lanz C., Schuster S.C., Wang J., Li S., Huang X., Cai T., Yu Z., Luo J., Zhao J., Bryant D.A.
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]"Isolation and characterization of the ndhF gene of Synechococcus sp. strain PCC 7002 and initial characterization of an interposon mutant."
Schluchter W.M., Zhao J., Bryant D.A.
J. Bacteriol. 175:3343-3352(1993) [PubMed: 8501038] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-18.

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Cross-references

Sequence databases

M86234 Genomic DNA. Translation: AAA27323.1.
CP000951 Genomic DNA. Translation: ACA98857.1.
M99378 Genomic DNA. Translation: AAA27310.1.
RefSeqYP_001734113.1.

3D structure databases

EntryMethodResolution (Å)ChainPositionsPDBsum
2B5OX-ray2.50A/B1-402[»]
ModBaseSearch...

Genome annotation databases

GeneID6056783.
GenomeReviewsGene locus SYNPCC7002_A0853 in contig CP000951_GR.
KEGGsyp:SYNPCC7002_A0853.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAP31973. GRMYIQD.

Family and domain databases

InterProIPR017927. Fd_Rdtase_FAD-bd.
IPR001709. Flavoprot_Pyr_Nucl_cyt_Rdtase.
IPR012146. Frd-NADP+_RD.
IPR015701. FRD_Red.
IPR001433. OxRdtase_FAD/NAD_bd.
IPR008213. Phycobilisome_lnk_CpcD-like.
[Graphical view]
PANTHERPTHR19384:SF1. FRD_Red. 1 hit.
PfamPF01383. CpcD. 1 hit.
PF00175. NAD_binding_1. 1 hit.
[Graphical view]
PIRSFPIRSF000361. Frd-NADP+_RD. 1 hit.
PRINTSPR00371. FPNCR.
PROSITEPS51441. CPCD_LIKE. 1 hit.
PS51384. FAD_FR. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameFENR_SYNP2
AccessionPrimary (citable) accession number: P31973
Secondary accession number(s): B1XII6
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: July 1, 1993
Last modified: June 16, 2009
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents