P31967 (CPCE_SYNP2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phycocyanobilin lyase subunit alpha
EC=4.-.-.-

Alternative name(s):
Phycocyanin operon protein CpcE

Gene names

Name:	cpcE
Ordered Locus Names:	SYNPCC7002_A2213

Organism

Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum) [Complete proteome] [HAMAP]

Taxonomic identifier

32049 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Cyanobacteria › Oscillatoriophycideae › Chroococcales › Synechococcus

Protein attributes

Sequence length	268 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Required for the chromophorylation of the cpcA gene product.
Subunit structure	CpcE and CpcF associate to form a lyase.
Sequence similarities	Belongs to the CpcE/RpcE/PecE family.

Ontologies

Keywords
Cellular component	Phycobilisome
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular_component	phycobilisome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	lyase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 268	268	Phycocyanobilin lyase subunit alpha		PRO_0000199270
Experimental info
	Sequence conflict	173	1	R → P in AAA27308. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P31967 [UniParc]. Last modified June 10, 2008. Version 2. Checksum: 9AD7AFC6A301D1DA	FASTA	268	29,233
	10 20 30 40 50 60 MSDWQMAEAW TLEEAIANIQ QTEDTGKRYY AAWWFGKFRV QDERAVNALL AALKDETDRS 70 80 90 100 110 120 PDGGYPLRRN AAKALGKLGN LAAVQPLIES LESPDYYVRE SAAQSLEMLG DRQAIPALQA 130 140 150 160 170 180 LLAGGVAAAV KAEGKPHLVQ PYEAVIEALG TIGATAAIAE IEPFLDHEFA KIRYAALRAL 190 200 210 220 230 240 YQLTQEAHYA EQLMEALNGN QLQLRRSALL DLGAIGYVPA GQAIAKAYAE NSLKLISLKG 250 260 ILESHLQRTA ETLDADGLQL LELMDSLL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The cpcE and cpcF genes of Synechococcus sp. PCC 7002. Construction and phenotypic characterization of interposon mutants." Zhou J., Gasparich G.E., Stirewalt V.L., de Lorimier R., Bryant D.A. J. Biol. Chem. 267:16138-16145(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], CHARACTERIZATION.
[2]	"Complete sequence of Synechococcus sp. PCC 7002." Li T., Zhao J., Zhao C., Liu Z., Zhao F., Marquardt J., Nomura C.T., Persson S., Detter J.C., Richardson P.M., Lanz C., Schuster S.C., Wang J., Li S., Huang X., Cai T., Yu Z., Luo J., Zhao J., Bryant D.A. Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27264 / PCC 7002 / PR-6.
[3]	"Phycocyanin alpha-subunit phycocyanobilin lyase." Fairchild C.D., Zhao J., Zhou J., Colson S.E., Bryant D.A., Glazer A.N. Proc. Natl. Acad. Sci. U.S.A. 89:7017-7021(1992) [PubMed] [Europe PMC] [Abstract] Cited for: CHARACTERIZATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M93569 Genomic DNA. Translation: AAA27308.1. CP000951 Genomic DNA. Translation: ACB00194.1.
RefSeq	YP_001735449.1. NC_010475.1.
3D structure databases
ProteinModelPortal	P31967.
ModBase	Search...
Protein-protein interaction databases
STRING	32049.SYNPCC7002_A2213.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACB00194; ACB00194; SYNPCC7002_A2213.
GeneID	6055870.
KEGG	syp:SYNPCC7002_A2213.
PATRIC	23819064. VBISynSp37135_2465.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1413.
HOGENOM	HOG000276576.
KO	K02288.
OMA	WLGRFRV.
ProtClustDB	CLSK892932.
Family and domain databases
Gene3D	1.25.10.10. 2 hits.
InterPro	IPR011989. ARM-like. IPR016024. ARM-type_fold. IPR004155. PBS_lyase_HEAT. [Graphical view]
Pfam	PF03130. HEAT_PBS. 4 hits. [Graphical view]
SMART	SM00567. EZ_HEAT. 6 hits. [Graphical view]
SUPFAM	SSF48371. ARM-type_fold. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CPCE_SYNP2

Accession

Primary (citable) accession number: P31967
Secondary accession number(s): B1XIU2

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 1993
Last sequence update:	June 10, 2008
Last modified:	May 1, 2013
This is version 63 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program