Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P31942

- HNRH3_HUMAN

UniProt

P31942 - HNRH3_HUMAN

Protein

Heterogeneous nuclear ribonucleoprotein H3

Gene

HNRNPH3

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 148 (01 Oct 2014)
      Sequence version 2 (19 Sep 2002)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Involved in the splicing process and participates in early heat shock-induced splicing arrest. Due to their great structural variations the different isoforms may possess different functions in the splicing reaction.

    GO - Molecular functioni

    1. nucleotide binding Source: InterPro
    2. poly(A) RNA binding Source: UniProtKB
    3. protein binding Source: UniProt
    4. RNA binding Source: UniProtKB

    GO - Biological processi

    1. epithelial cell differentiation Source: UniProt
    2. mRNA splicing, via spliceosome Source: UniProtKB
    3. RNA processing Source: ProtInc
    4. RNA splicing Source: ProtInc

    Keywords - Molecular functioni

    Ribonucleoprotein

    Keywords - Biological processi

    mRNA processing

    Keywords - Ligandi

    RNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Heterogeneous nuclear ribonucleoprotein H3
    Short name:
    hnRNP H3
    Alternative name(s):
    Heterogeneous nuclear ribonucleoprotein 2H9
    Short name:
    hnRNP 2H9
    Gene namesi
    Name:HNRNPH3
    Synonyms:HNRPH3
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 10

    Organism-specific databases

    HGNCiHGNC:5043. HNRNPH3.

    Subcellular locationi

    Nucleus 1 Publication

    GO - Cellular componenti

    1. nucleus Source: UniProt
    2. spliceosomal complex Source: UniProtKB

    Keywords - Cellular componenti

    Nucleus

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA162391325.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 346346Heterogeneous nuclear ribonucleoprotein H3PRO_0000081861Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei1 – 11N-acetylmethionine1 Publication
    Modified residuei121 – 1211Asymmetric dimethylarginine1 Publication
    Modified residuei216 – 2161Phosphoserine7 Publications
    Modified residuei287 – 2871Omega-N-methylarginine1 Publication
    Modified residuei298 – 2981Phosphoserine3 Publications
    Modified residuei314 – 3141Phosphothreonine1 Publication

    Keywords - PTMi

    Acetylation, Methylation, Phosphoprotein

    Proteomic databases

    MaxQBiP31942.
    PaxDbiP31942.
    PRIDEiP31942.

    PTM databases

    PhosphoSiteiP31942.

    Expressioni

    Gene expression databases

    ArrayExpressiP31942.
    BgeeiP31942.
    CleanExiHS_HNRNPH3.
    GenevestigatoriP31942.

    Organism-specific databases

    HPAiHPA038264.

    Interactioni

    Protein-protein interaction databases

    BioGridi109430. 65 interactions.
    IntActiP31942. 46 interactions.
    MINTiMINT-5004191.

    Structurei

    3D structure databases

    ProteinModelPortaliP31942.
    SMRiP31942. Positions 10-97, 194-270.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini16 – 9378RRM 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini195 – 27076RRM 2PROSITE-ProRule annotationAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi108 – 344237Gly-richAdd
    BLAST

    Sequence similaritiesi

    Contains 2 RRM (RNA recognition motif) domains.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    eggNOGiNOG262593.
    HOVERGENiHBG055557.
    InParanoidiP31942.
    KOiK12898.
    OMAiPYDRPLG.
    OrthoDBiEOG7BS4BZ.
    PhylomeDBiP31942.
    TreeFamiTF316157.

    Family and domain databases

    Gene3Di3.30.70.330. 2 hits.
    InterProiIPR012677. Nucleotide-bd_a/b_plait.
    IPR000504. RRM_dom.
    [Graphical view]
    SMARTiSM00360. RRM. 2 hits.
    [Graphical view]
    PROSITEiPS50102. RRM. 2 hits.
    [Graphical view]

    Sequences (6)i

    Sequence statusi: Complete.

    This entry describes 6 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: P31942-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MDWVMKHNGP NDASDGTVRL RGLPFGCSKE EIVQFFQGLE IVPNGITLTM    50
    DYQGRSTGEA FVQFASKEIA ENALGKHKER IGHRYIEIFR SSRSEIKGFY 100
    DPPRRLLGQR PGPYDRPIGG RGGYYGAGRG SMYDRMRRGG DGYDGGYGGF 150
    DDYGGYNNYG YGNDGFDDRM RDGRGMGGHG YGGAGDASSG FHGGHFVHMR 200
    GLPFRATEND IANFFSPLNP IRVHIDIGAD GRATGEADVE FVTHEDAVAA 250
    MSKDKNNMQH RYIELFLNST PGGGSGMGGS GMGGYGRDGM DNQGGYGSVG 300
    RMGMGNNYSG GYGTPDGLGG YGRGGGGSGG YYGQGGMSGG GWRGMY 346
    Length:346
    Mass (Da):36,926
    Last modified:September 19, 2002 - v2
    Checksum:iF7D14C2947930E9E
    GO
    Isoform 2 (identifier: P31942-2) [UniParc]FASTAAdd to Basket

    Also known as: 2H9A

    The sequence of this isoform differs from the canonical sequence as follows:
         132-146: Missing.

    Show »
    Length:331
    Mass (Da):35,239
    Checksum:iA3BA8D0F5FC07369
    GO
    Isoform 3 (identifier: P31942-3) [UniParc]FASTAAdd to Basket

    Also known as: 2H9B

    The sequence of this isoform differs from the canonical sequence as follows:
         1-49: Missing.

    Show »
    Length:297
    Mass (Da):31,525
    Checksum:iAAE63A29063E5153
    GO
    Isoform 4 (identifier: P31942-4) [UniParc]FASTAAdd to Basket

    Also known as: 2H9C

    The sequence of this isoform differs from the canonical sequence as follows:
         1-131: Missing.

    Show »
    Length:215
    Mass (Da):22,322
    Checksum:i969F8FE2710D2646
    GO
    Isoform 5 (identifier: P31942-5) [UniParc]FASTAAdd to Basket

    Also known as: 2H9D

    The sequence of this isoform differs from the canonical sequence as follows:
         1-131: Missing.
         259-276: QHRYIELFLNSTPGGGSG → RKWCLWHTILFPKREFIK
         277-346: Missing.

    Show »
    Length:145
    Mass (Da):16,084
    Checksum:i286234CBE7C9C996
    GO
    Isoform 6 (identifier: P31942-6) [UniParc]FASTAAdd to Basket

    Also known as: 2H9E

    The sequence of this isoform differs from the canonical sequence as follows:
         1-137: Missing.
         138-145: RGGDGYDG → MCFSLNYT
         259-276: QHRYIELFLNSTPGGGSG → RKWCLWHTILFPKREFIK
         277-346: Missing.

    Show »
    Length:139
    Mass (Da):15,413
    Checksum:iF1E137E637675D93
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti163 – 1631N → S.
    Corresponds to variant rs2273903 [ dbSNP | Ensembl ].
    VAR_020333
    Natural varianti284 – 2841G → A.
    Corresponds to variant rs16925347 [ dbSNP | Ensembl ].
    VAR_052226

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 137137Missing in isoform 6. 1 PublicationVSP_005841Add
    BLAST
    Alternative sequencei1 – 131131Missing in isoform 4 and isoform 5. 3 PublicationsVSP_005839Add
    BLAST
    Alternative sequencei1 – 4949Missing in isoform 3. 1 PublicationVSP_005838Add
    BLAST
    Alternative sequencei132 – 14615Missing in isoform 2. 3 PublicationsVSP_005840Add
    BLAST
    Alternative sequencei138 – 1458RGGDGYDG → MCFSLNYT in isoform 6. 1 PublicationVSP_005842
    Alternative sequencei259 – 27618QHRYI…GGGSG → RKWCLWHTILFPKREFIK in isoform 5 and isoform 6. 1 PublicationVSP_005843Add
    BLAST
    Alternative sequencei277 – 34670Missing in isoform 5 and isoform 6. 1 PublicationVSP_005844Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L32610 mRNA. Translation: AAD45179.1.
    AF132360 Genomic DNA. Translation: AAF68843.1.
    AF132360 Genomic DNA. Translation: AAF68844.1.
    AF132360 Genomic DNA. Translation: AAF68845.1.
    AF132360 Genomic DNA. Translation: AAF68846.1.
    AF132360 Genomic DNA. Translation: AAF68847.1.
    AF132360 Genomic DNA. Translation: AAF68848.1.
    AF132361 mRNA. Translation: AAF68849.1.
    AF132362 mRNA. Translation: AAF68850.1.
    AF132363 mRNA. Translation: AAF68851.1.
    AF132364 mRNA. Translation: AAF68852.1.
    AK091411 mRNA. Translation: BAG52353.1.
    AK291547 mRNA. Translation: BAF84236.1.
    AL117395 mRNA. Translation: CAB55897.1.
    CH471083 Genomic DNA. Translation: EAW54281.1.
    CH471083 Genomic DNA. Translation: EAW54282.1.
    BC004511 mRNA. Translation: AAH04511.2.
    BC039824 mRNA. Translation: AAH39824.1.
    CCDSiCCDS7278.1. [P31942-1]
    CCDS7279.1. [P31942-2]
    PIRiT17207.
    RefSeqiNP_036339.1. NM_012207.2. [P31942-1]
    NP_067676.2. NM_021644.3. [P31942-2]
    XP_005269805.1. XM_005269748.2. [P31942-1]
    XP_005269806.1. XM_005269749.2. [P31942-2]
    XP_005269808.1. XM_005269751.2. [P31942-4]
    XP_005269809.1. XM_005269752.2. [P31942-4]
    XP_006717879.1. XM_006717816.1. [P31942-1]
    XP_006717880.1. XM_006717817.1. [P31942-2]
    UniGeneiHs.643472.

    Genome annotation databases

    EnsembliENST00000265866; ENSP00000265866; ENSG00000096746. [P31942-1]
    ENST00000354695; ENSP00000346726; ENSG00000096746. [P31942-2]
    GeneIDi3189.
    KEGGihsa:3189.
    UCSCiuc001jnw.4. human. [P31942-1]
    uc001jnx.4. human. [P31942-2]

    Polymorphism databases

    DMDMi23503095.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L32610 mRNA. Translation: AAD45179.1 .
    AF132360 Genomic DNA. Translation: AAF68843.1 .
    AF132360 Genomic DNA. Translation: AAF68844.1 .
    AF132360 Genomic DNA. Translation: AAF68845.1 .
    AF132360 Genomic DNA. Translation: AAF68846.1 .
    AF132360 Genomic DNA. Translation: AAF68847.1 .
    AF132360 Genomic DNA. Translation: AAF68848.1 .
    AF132361 mRNA. Translation: AAF68849.1 .
    AF132362 mRNA. Translation: AAF68850.1 .
    AF132363 mRNA. Translation: AAF68851.1 .
    AF132364 mRNA. Translation: AAF68852.1 .
    AK091411 mRNA. Translation: BAG52353.1 .
    AK291547 mRNA. Translation: BAF84236.1 .
    AL117395 mRNA. Translation: CAB55897.1 .
    CH471083 Genomic DNA. Translation: EAW54281.1 .
    CH471083 Genomic DNA. Translation: EAW54282.1 .
    BC004511 mRNA. Translation: AAH04511.2 .
    BC039824 mRNA. Translation: AAH39824.1 .
    CCDSi CCDS7278.1. [P31942-1 ]
    CCDS7279.1. [P31942-2 ]
    PIRi T17207.
    RefSeqi NP_036339.1. NM_012207.2. [P31942-1 ]
    NP_067676.2. NM_021644.3. [P31942-2 ]
    XP_005269805.1. XM_005269748.2. [P31942-1 ]
    XP_005269806.1. XM_005269749.2. [P31942-2 ]
    XP_005269808.1. XM_005269751.2. [P31942-4 ]
    XP_005269809.1. XM_005269752.2. [P31942-4 ]
    XP_006717879.1. XM_006717816.1. [P31942-1 ]
    XP_006717880.1. XM_006717817.1. [P31942-2 ]
    UniGenei Hs.643472.

    3D structure databases

    ProteinModelPortali P31942.
    SMRi P31942. Positions 10-97, 194-270.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 109430. 65 interactions.
    IntActi P31942. 46 interactions.
    MINTi MINT-5004191.

    PTM databases

    PhosphoSitei P31942.

    Polymorphism databases

    DMDMi 23503095.

    Proteomic databases

    MaxQBi P31942.
    PaxDbi P31942.
    PRIDEi P31942.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000265866 ; ENSP00000265866 ; ENSG00000096746 . [P31942-1 ]
    ENST00000354695 ; ENSP00000346726 ; ENSG00000096746 . [P31942-2 ]
    GeneIDi 3189.
    KEGGi hsa:3189.
    UCSCi uc001jnw.4. human. [P31942-1 ]
    uc001jnx.4. human. [P31942-2 ]

    Organism-specific databases

    CTDi 3189.
    GeneCardsi GC10P070090.
    HGNCi HGNC:5043. HNRNPH3.
    HPAi HPA038264.
    MIMi 602324. gene.
    neXtProti NX_P31942.
    PharmGKBi PA162391325.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG262593.
    HOVERGENi HBG055557.
    InParanoidi P31942.
    KOi K12898.
    OMAi PYDRPLG.
    OrthoDBi EOG7BS4BZ.
    PhylomeDBi P31942.
    TreeFami TF316157.

    Miscellaneous databases

    ChiTaRSi HNRNPH3. human.
    GeneWikii HNRPH3.
    GenomeRNAii 3189.
    NextBioi 12680.
    PROi P31942.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi P31942.
    Bgeei P31942.
    CleanExi HS_HNRNPH3.
    Genevestigatori P31942.

    Family and domain databases

    Gene3Di 3.30.70.330. 2 hits.
    InterProi IPR012677. Nucleotide-bd_a/b_plait.
    IPR000504. RRM_dom.
    [Graphical view ]
    SMARTi SM00360. RRM. 2 hits.
    [Graphical view ]
    PROSITEi PS50102. RRM. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning of human 2H9 heterogeneous nuclear ribonucleoproteins. Relation with splicing and early heat shock-induced splicing arrest."
      Mahe D., Mahl P., Gattoni R., Fischer N., Mattei M.-G., Stevenin J., Fuchs J.-P.
      J. Biol. Chem. 272:1827-1836(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), SUBCELLULAR LOCATION.
    2. "The hnRNP 2H9 gene, which is involved in the splicing reaction, is a multiply spliced gene."
      Honore B.
      Biochim. Biophys. Acta 1492:108-119(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORMS 1; 2; 3; 4; 5 AND 6).
    3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 4).
      Tissue: Brain and Placenta.
    4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4).
      Tissue: Uterus.
    5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
      Tissue: Ovary and Skin.
    7. Bienvenut W.V., Lilla S., von Kriegsheim A., Lempens A., Kolch W.
      Submitted (DEC-2008) to UniProtKB
      Cited for: PROTEIN SEQUENCE OF 1-6; 56-76; 85-90; 98-104; 175-200; 223-253 AND 262-323, ACETYLATION AT MET-1, METHYLATION AT ARG-287, IDENTIFICATION BY MASS SPECTROMETRY.
      Tissue: Ovarian carcinoma.
    8. Lubec G., Vishwanath V., Chen W.-Q., Sun Y.
      Submitted (DEC-2008) to UniProtKB
      Cited for: PROTEIN SEQUENCE OF 56-67; 206-222; 233-253 AND 262-287, IDENTIFICATION BY MASS SPECTROMETRY.
      Tissue: Brain, Cajal-Retzius cell and Fetal brain cortex.
    9. "Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes."
      Rasmussen H.H., van Damme J., Puype M., Gesser B., Celis J.E., Vandekerckhove J.
      Electrophoresis 13:960-969(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 94-104 AND 288-298.
      Tissue: Keratinocyte.
    10. "A post-translational modification of nuclear proteins, N(G),N(G)-dimethyl-Arg, found in a natural HLA class I peptide ligand."
      Yague J., Vazquez J., Lopez de Castro J.A.
      Protein Sci. 9:2210-2217(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 116-127, METHYLATION AT ARG-121.
    11. "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells."
      Rush J., Moritz A., Lee K.A., Guo A., Goss V.L., Spek E.J., Zhang H., Zha X.-M., Polakiewicz R.D., Comb M.J.
      Nat. Biotechnol. 23:94-101(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    12. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
      Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-216, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    13. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
      Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R., Greff Z., Keri G., Stemmann O., Mann M.
      Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-216, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    14. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-216, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    15. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-216, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    16. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
      Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-216; SER-298 AND THR-314, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Leukemic T-cell.
    17. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-216 AND SER-298, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    18. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    19. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
      Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-216 AND SER-298, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiHNRH3_HUMAN
    AccessioniPrimary (citable) accession number: P31942
    Secondary accession number(s): A8K682
    , B3KRE1, Q9BSX1, Q9NP53, Q9NP96, Q9NPA7, Q9NPI4, Q9UFU4, Q9Y4J5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 1, 1993
    Last sequence update: September 19, 2002
    Last modified: October 1, 2014
    This is version 148 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. Human chromosome 10
      Human chromosome 10: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3