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Protein

Inner membrane ABC transporter ATP-binding protein YddA

Gene

yddA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi400 – 407ATPPROSITE-ProRule annotation8

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciEcoCyc:YDDA-MONOMER.
ECOL316407:JW5242-MONOMER.

Protein family/group databases

TCDBi3.A.1.203.11. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane ABC transporter ATP-binding protein YddA
Alternative name(s):
CDS102
Gene namesi
Name:yddA
Ordered Locus Names:b1496, JW5242
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11742. yddA.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 3CytoplasmicSequence analysis3
Transmembranei4 – 24HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini25 – 31PeriplasmicSequence analysis7
Transmembranei32 – 52HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini53 – 70CytoplasmicSequence analysisAdd BLAST18
Transmembranei71 – 91HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini92 – 151PeriplasmicSequence analysisAdd BLAST60
Transmembranei152 – 172HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini173 – 187CytoplasmicSequence analysisAdd BLAST15
Transmembranei188 – 208HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini209 – 290PeriplasmicSequence analysisAdd BLAST82
Transmembranei291 – 311HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini312 – 561CytoplasmicSequence analysisAdd BLAST250

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000931631 – 561Inner membrane ABC transporter ATP-binding protein YddAAdd BLAST561

Proteomic databases

PaxDbiP31826.
PRIDEiP31826.

Interactioni

Protein-protein interaction databases

BioGridi4260785. 207 interactors.
STRINGi511145.b1496.

Structurei

3D structure databases

ProteinModelPortaliP31826.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 337ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST303
Domaini367 – 561ABC transporterPROSITE-ProRule annotationAdd BLAST195

Sequence similaritiesi

Belongs to the ABC transporter superfamily.Curated
Contains 1 ABC transmembrane type-1 domain.PROSITE-ProRule annotation
Contains 1 ABC transporter domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CQ0. Bacteria.
COG4178. LUCA.
HOGENOMiHOG000255118.
InParanoidiP31826.
KOiK02471.
OMAiVHIRDNA.
PhylomeDBiP31826.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF06472. ABC_membrane_2. 1 hit.
PF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF90123. SSF90123. 1 hit.
PROSITEiPS50929. ABC_TM1F. 1 hit.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P31826-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MITIPITLRM LIAKYLCLLK PFWLRKNNKT SVLLIIIILA MILGVVKIQV
60 70 80 90 100
WLNDWNNDFF NALSQKETDK LWQLVLWFPA LLGIFVLISV NKTWLIKLLT
110 120 130 140 150
IRWREWLTDY YLNRWFADKN YYFTQIYGEH KNTDNPDQRI AEDILLLISK
160 170 180 190 200
TLSLSFGFIQ SLSMLITFTV ILWESAGTLS FTVGGTEWNI QGYMVYTVVL
210 220 230 240 250
IVIGGTLFTH KVGKRIRPLN VEKQRSEATF RTNLVQHNKQ AELIALSNAE
260 270 280 290 300
SLQRQELSDN FHTIKENWHR LMNRQRWLDY WQNIYSRSLS VLPYFLLLPQ
310 320 330 340 350
FISGQINLGG LMKSRQAFML VSNNLSWFIY KYDELAELAA VIDRLYEFHQ
360 370 380 390 400
LTEQRPTNKP KNCQHAVQVA DASIRTPDNK IILENLNFHV SPGKWLLLKG
410 420 430 440 450
YSGAGKTTLL KTLSHCWPWF KGDISSPADS WYVSQTPLIK TGLLKEIICK
460 470 480 490 500
ALPLPVDDKS LSEVLHQVGL GKLAARIHDH DRWGDILSSG EKQRIALARL
510 520 530 540 550
ILRRPKWIFL DETTSHLEEQ EAIRLLRLVR EKLPTSGVIM VTHQPGVWNL
560
ADDICDISAV L
Length:561
Mass (Da):64,985
Last modified:November 1, 1997 - v2
Checksum:i92E47426294413F5
GO

Sequence cautioni

The sequence CAA50732 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74569.1.
AP009048 Genomic DNA. Translation: BAA15167.2.
X71917 Genomic DNA. Translation: CAA50732.1. Different initiation.
PIRiC64903.
RefSeqiNP_416013.1. NC_000913.3.
WP_000628576.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74569; AAC74569; b1496.
BAA15167; BAA15167; BAA15167.
GeneIDi945945.
KEGGiecj:JW5242.
eco:b1496.
PATRICi32118286. VBIEscCol129921_1563.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74569.1.
AP009048 Genomic DNA. Translation: BAA15167.2.
X71917 Genomic DNA. Translation: CAA50732.1. Different initiation.
PIRiC64903.
RefSeqiNP_416013.1. NC_000913.3.
WP_000628576.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP31826.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260785. 207 interactors.
STRINGi511145.b1496.

Protein family/group databases

TCDBi3.A.1.203.11. the atp-binding cassette (abc) superfamily.

Proteomic databases

PaxDbiP31826.
PRIDEiP31826.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74569; AAC74569; b1496.
BAA15167; BAA15167; BAA15167.
GeneIDi945945.
KEGGiecj:JW5242.
eco:b1496.
PATRICi32118286. VBIEscCol129921_1563.

Organism-specific databases

EchoBASEiEB1693.
EcoGeneiEG11742. yddA.

Phylogenomic databases

eggNOGiENOG4105CQ0. Bacteria.
COG4178. LUCA.
HOGENOMiHOG000255118.
InParanoidiP31826.
KOiK02471.
OMAiVHIRDNA.
PhylomeDBiP31826.

Enzyme and pathway databases

BioCyciEcoCyc:YDDA-MONOMER.
ECOL316407:JW5242-MONOMER.

Miscellaneous databases

PROiP31826.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF06472. ABC_membrane_2. 1 hit.
PF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF90123. SSF90123. 1 hit.
PROSITEiPS50929. ABC_TM1F. 1 hit.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYDDA_ECOLI
AccessioniPrimary (citable) accession number: P31826
Secondary accession number(s): P76133, P76876
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: November 1, 1997
Last modified: November 2, 2016
This is version 133 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.