P31778 (HRPB_RALSO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Regulatory protein HrpB

Gene names

Name:	hrpB
Ordered Locus Names:	RSp0873
ORF Names:	RS01644

Encoded on

Plasmid megaplasmid Rsp

Organism

Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum) [Complete proteome] [HAMAP]

Taxonomic identifier

267608 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Ralstonia › Ralstonia solanacearum

Protein attributes

Sequence length	477 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Function	Positive regulation of hypersensitive response genes involved in plant pathogenicity and partly of its own synthesis in minimal medium.
Sequence similarities	Contains 1 HTH araC/xylS-type DNA-binding domain.

Ontologies

Keywords
Biological process	Hypersensitive response elicitation Transcription Transcription regulation
Ligand	DNA-binding
Molecular function	Activator
Technical term	Complete proteome Plasmid
Gene Ontology (GO)
Biological_process	modulation by symbiont of host defense-related programmed cell death Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular_function	sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 477	477	Regulatory protein HrpB		PRO_0000194525
Regions
	DNA binding	392 – 411	20	H-T-H motif By similarity

Sequences

	Sequence		Length	Mass (Da)
	P31778 [UniParc]. Last modified July 1, 1993. Version 1. Checksum: D4E5FECA713A511B	FASTA	477	53,268
	10 20 30 40 50 60 MLGNIYFALA SGLAARERLP EYANAVFAAD FDRAYQLVDH HSSQRGKSDD YAGVLAMADA 70 80 90 100 110 120 SLLLECDEEA EEGFRLAQRL IRHSDDQLRV VSCRNTGWQA LLRDRYAAAA SCFSRMAEDD 130 140 150 160 170 180 GATWTQQVEG LIGLALVHHQ LGQQDASDDA LRAAREAADG RSDRGWLATI DLIIYEFAVQ 190 200 210 220 230 240 AGIRCSNRLL EHAFWQSAEM GATLLANHGG RNGWTPTVSQ GVPMPALIQR RAEYLSLLRR 250 260 270 280 290 300 MADGDRAAID PLMATLNHSR KLGSRLLMQT KVEVVLAALS GEQYDVAGRV FDQICNRETT 310 320 330 340 350 360 YGARRWNFDF LYCRAKMAAQ RGDAAGALKF YTTYMQDALR CLRTETVNVR RASAAVPVAS 370 380 390 400 410 420 RASDDVSARL SAKYRRAYRY IIENIERSDL TTREVAAHIN VTERALQLAF KSAVGMSPSS 430 440 450 460 470 VIRRMRLEGI RSDLLDSERN PSNIIDTASR WGIRSRSALV KGYRKQFNEA PSETIWR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Evidence that the hrpB gene encodes a positive regulator of pathogenicity genes from Pseudomonas solanacearum." Genin S., Gough C.L., Zischek C., Boucher C.A. Mol. Microbiol. 6:3065-3076(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: GMI1000.
[2]	"Genome sequence of the plant pathogen Ralstonia solanacearum." Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M., Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M., Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M., Moisan A. , Robert C., Saurin W., Schiex T., Siguier P., Thebault P., Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A. Nature 415:497-502(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GMI1000.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ245811 Genomic DNA. Translation: CAB58260.1. AL646053 Genomic DNA. Translation: CAD18024.1.
PIR	S28010.
RefSeq	NP_522434.1. NC_003296.1.
3D structure databases
ProteinModelPortal	P31778.
ModBase	Search...
Protein-protein interaction databases
STRING	267608.RSp0873.
Protein family/group databases
AraC-XylS	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAD18024; CAD18024; RSp0873.
GeneID	1223180.
KEGG	rso:RSp0873.
PATRIC	20267343. VBIRalSol70888_4343.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2207.
HOGENOM	HOG000226752.
OMA	SCRNTGW.
ProtClustDB	CLSK630583.
Family and domain databases
Gene3D	1.10.10.60. 1 hit.
InterPro	IPR009057. Homeodomain-like. IPR018060. HTH_AraC. IPR018062. HTH_AraC-typ_CS. [Graphical view]
SMART	SM00342. HTH_ARAC. 1 hit. [Graphical view]
SUPFAM	SSF46689. Homeodomain_like. 1 hit.
PROSITE	PS00041. HTH_ARAC_FAMILY_1. 1 hit. PS01124. HTH_ARAC_FAMILY_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HRPB_RALSO

Accession

Primary (citable) accession number: P31778

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 1993
Last sequence update:	July 1, 1993
Last modified:	May 1, 2013
This is version 92 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program