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P31766

- GALR_HAEIN

UniProt

P31766 - GALR_HAEIN

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Protein
HTH-type transcriptional regulator GalR
Gene
galR, galS, HI_0821
Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 3 out of 5 - Protein predictedi

Functioni

Repressor of the galactose operon. Binds galactose as an inducer.

Pathwayi

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi4 – 2320H-T-H motif Reviewed prediction
Add
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. sequence-specific DNA binding transcription factor activity Source: InterPro

GO - Biological processi

  1. galactose metabolic process Source: UniProtKB-UniPathway
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Carbohydrate metabolism, Galactose metabolism, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

UniPathwayiUPA00214.

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional regulator GalR
Alternative name(s):
Galactose operon repressor
Gene namesi
Name:galR
Synonyms:galS
Ordered Locus Names:HI_0821
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000000579: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 332332HTH-type transcriptional regulator GalR
PRO_0000107953Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi71421.HI0821.

Structurei

3D structure databases

ProteinModelPortaliP31766.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 5656HTH lacI-type
Add
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1609.
KOiK02529.
OMAiAFDDAPW.
OrthoDBiEOG6SJJMM.
PhylomeDBiP31766.

Family and domain databases

Gene3Di1.10.260.40. 1 hit.
InterProiIPR010982. Lambda_DNA-bd_dom.
IPR028082. Peripla_BP_I.
IPR000843. Tscrpt_reg_HTH_LacI.
[Graphical view]
PfamiPF00356. LacI. 1 hit.
[Graphical view]
PRINTSiPR00036. HTHLACI.
SMARTiSM00354. HTH_LACI. 1 hit.
[Graphical view]
SUPFAMiSSF47413. SSF47413. 1 hit.
SSF53822. SSF53822. 1 hit.
PROSITEiPS00356. HTH_LACI_1. 1 hit.
PS50932. HTH_LACI_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P31766-1 [UniParc]FASTAAdd to Basket

« Hide

MSTIRDVAKL ANVSVATVSR VLNHSLSVSE NTRLVVEQAI AQLAYQPNAN    50
AQALAVQNTD TIGVVVTDVT DAFFAILVKA VDKVAEAHQK TILIGIGYHH 100
AEKEREAINT LLRKRCSSLV VHSKALSDDE LSHYLNTVQG MVIINRVIKG 150
YEHRCVSLDN QKGTYLATEM LIRYGHQHIA YIGSNHAIFD EVERRNGYLA 200
ALKDHNYPII EQAITLNSPD FEGGEKAMID LLSYNKNLTA VVAYNDSMAA 250
GAISVLNENN ISVPSQFSII GFDDMPIARY LIPKLTTIRY PIDLMATYAA 300
KLALSLTDEK IITPPVVQFN PTLVRRFSVE SR 332
Length:332
Mass (Da):36,708
Last modified:November 1, 1995 - v2
Checksum:i0F431000946AF8A5
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti35 – 351V → A in CAA46729. 1 Publication
Sequence conflicti38 – 381Q → R in CAA46729. 1 Publication
Sequence conflicti208 – 2081P → L in CAA46729. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X65934 Genomic DNA. Translation: CAA46729.1.
L42023 Genomic DNA. Translation: AAC22480.1.
PIRiF64096.
RefSeqiNP_438981.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC22480; AAC22480; HI_0821.
GeneIDi949832.
KEGGihin:HI0821.
PATRICi20190297. VBIHaeInf48452_0862.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X65934 Genomic DNA. Translation: CAA46729.1 .
L42023 Genomic DNA. Translation: AAC22480.1 .
PIRi F64096.
RefSeqi NP_438981.1. NC_000907.1.

3D structure databases

ProteinModelPortali P31766.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 71421.HI0821.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC22480 ; AAC22480 ; HI_0821 .
GeneIDi 949832.
KEGGi hin:HI0821.
PATRICi 20190297. VBIHaeInf48452_0862.

Phylogenomic databases

eggNOGi COG1609.
KOi K02529.
OMAi AFDDAPW.
OrthoDBi EOG6SJJMM.
PhylomeDBi P31766.

Enzyme and pathway databases

UniPathwayi UPA00214 .

Family and domain databases

Gene3Di 1.10.260.40. 1 hit.
InterProi IPR010982. Lambda_DNA-bd_dom.
IPR028082. Peripla_BP_I.
IPR000843. Tscrpt_reg_HTH_LacI.
[Graphical view ]
Pfami PF00356. LacI. 1 hit.
[Graphical view ]
PRINTSi PR00036. HTHLACI.
SMARTi SM00354. HTH_LACI. 1 hit.
[Graphical view ]
SUPFAMi SSF47413. SSF47413. 1 hit.
SSF53822. SSF53822. 1 hit.
PROSITEi PS00356. HTH_LACI_1. 1 hit.
PS50932. HTH_LACI_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The gal locus from Haemophilus influenzae: cloning, sequencing and the use of gal mutants to study lipopolysaccharide."
    Maskell D.J., Szabo M.J., Deadman M.E., Moxon E.R.
    Mol. Microbiol. 6:3051-3063(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: RM 7004 / Serotype B.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Entry informationi

Entry nameiGALR_HAEIN
AccessioniPrimary (citable) accession number: P31766
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: November 1, 1995
Last modified: July 9, 2014
This is version 103 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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