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Protein

HTH-type transcriptional regulator GalR

Gene

galR

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score: -Protein predictedi

Functioni

Repressor of the galactose operon. Binds galactose as an inducer.

Pathwayi: galactose metabolism

This protein regulates the pathway galactose metabolism, which is part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the pathway galactose metabolism and in Carbohydrate metabolism.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi4 – 23H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Repressor
Biological processCarbohydrate metabolism, Galactose metabolism, Transcription, Transcription regulation

Enzyme and pathway databases

BioCyciHINF71421:G1GJ1-862-MONOMER
UniPathwayiUPA00214

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional regulator GalR
Alternative name(s):
Galactose operon repressor
Gene namesi
Name:galR
Synonyms:galS
Ordered Locus Names:HI_0821
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000000579 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001079531 – 332HTH-type transcriptional regulator GalRAdd BLAST332

Interactioni

Protein-protein interaction databases

STRINGi71421.HI0821

Structurei

3D structure databases

ProteinModelPortaliP31766
SMRiP31766
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 56HTH lacI-typePROSITE-ProRule annotationAdd BLAST56

Phylogenomic databases

eggNOGiENOG41060NJ Bacteria
COG1609 LUCA
KOiK02529
OMAiMHGVETA
PhylomeDBiP31766

Family and domain databases

CDDicd01392 HTH_LacI, 1 hit
InterProiView protein in InterPro
IPR000843 HTH_LacI
IPR010982 Lambda_DNA-bd_dom_sf
IPR028082 Peripla_BP_I
PfamiView protein in Pfam
PF00356 LacI, 1 hit
PRINTSiPR00036 HTHLACI
SMARTiView protein in SMART
SM00354 HTH_LACI, 1 hit
SUPFAMiSSF47413 SSF47413, 1 hit
SSF53822 SSF53822, 1 hit
PROSITEiView protein in PROSITE
PS00356 HTH_LACI_1, 1 hit
PS50932 HTH_LACI_2, 1 hit

Sequencei

Sequence statusi: Complete.

P31766-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTIRDVAKL ANVSVATVSR VLNHSLSVSE NTRLVVEQAI AQLAYQPNAN
60 70 80 90 100
AQALAVQNTD TIGVVVTDVT DAFFAILVKA VDKVAEAHQK TILIGIGYHH
110 120 130 140 150
AEKEREAINT LLRKRCSSLV VHSKALSDDE LSHYLNTVQG MVIINRVIKG
160 170 180 190 200
YEHRCVSLDN QKGTYLATEM LIRYGHQHIA YIGSNHAIFD EVERRNGYLA
210 220 230 240 250
ALKDHNYPII EQAITLNSPD FEGGEKAMID LLSYNKNLTA VVAYNDSMAA
260 270 280 290 300
GAISVLNENN ISVPSQFSII GFDDMPIARY LIPKLTTIRY PIDLMATYAA
310 320 330
KLALSLTDEK IITPPVVQFN PTLVRRFSVE SR
Length:332
Mass (Da):36,708
Last modified:November 1, 1995 - v2
Checksum:i0F431000946AF8A5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti35V → A in CAA46729 (PubMed:1282642).Curated1
Sequence conflicti38Q → R in CAA46729 (PubMed:1282642).Curated1
Sequence conflicti208P → L in CAA46729 (PubMed:1282642).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X65934 Genomic DNA Translation: CAA46729.1
L42023 Genomic DNA Translation: AAC22480.1
PIRiF64096
RefSeqiNP_438981.1, NC_000907.1
WP_005663077.1, NC_000907.1

Genome annotation databases

EnsemblBacteriaiAAC22480; AAC22480; HI_0821
GeneIDi949832
KEGGihin:HI0821
PATRICifig|71421.8.peg.862

Similar proteinsi

Entry informationi

Entry nameiGALR_HAEIN
AccessioniPrimary (citable) accession number: P31766
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: November 1, 1995
Last modified: March 28, 2018
This is version 118 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health