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Protein

Putative metabolite transport protein YaaU

Gene

yaaU

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

  • organic hydroxy compound transport Source: GO_Central
  • response to oxidative stress Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:YAAU-MONOMER.
ECOL316407:JW0044-MONOMER.

Protein family/group databases

TCDBi2.A.1.1.114. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Putative metabolite transport protein YaaU
Gene namesi
Name:yaaU
Synonyms:yabE
Ordered Locus Names:b0045, JW0044
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11566. yaaU.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 18CytoplasmicSequence analysisAdd BLAST18
Transmembranei19 – 39Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini40 – 53PeriplasmicSequence analysisAdd BLAST14
Transmembranei54 – 74Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini75 – 84CytoplasmicSequence analysis10
Transmembranei85 – 105Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini106 – 113PeriplasmicSequence analysis8
Transmembranei114 – 134Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini135 – 145CytoplasmicSequence analysisAdd BLAST11
Transmembranei146 – 166Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini167 – 173PeriplasmicSequence analysis7
Transmembranei174 – 194Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini195 – 241CytoplasmicSequence analysisAdd BLAST47
Transmembranei242 – 262Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini263 – 282PeriplasmicSequence analysisAdd BLAST20
Transmembranei283 – 303Helical; Name=8Sequence analysisAdd BLAST21
Topological domaini304 – 309CytoplasmicSequence analysis6
Transmembranei310 – 329Helical; Name=9Sequence analysisAdd BLAST20
Topological domaini330 – 334PeriplasmicSequence analysis5
Transmembranei335 – 357Helical; Name=10Sequence analysisAdd BLAST23
Topological domaini358 – 373CytoplasmicSequence analysisAdd BLAST16
Transmembranei374 – 394Helical; Name=11Sequence analysisAdd BLAST21
Topological domaini395 – 401PeriplasmicSequence analysis7
Transmembranei402 – 422Helical; Name=12Sequence analysisAdd BLAST21
Topological domaini423 – 443CytoplasmicSequence analysisAdd BLAST21

GO - Cellular componenti

  • integral component of membrane Source: GO_Central
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000504811 – 443Putative metabolite transport protein YaaUAdd BLAST443

Proteomic databases

PaxDbiP31679.
PRIDEiP31679.

Interactioni

Protein-protein interaction databases

BioGridi4262202. 172 interactors.
STRINGi511145.b0045.

Structurei

3D structure databases

ProteinModelPortaliP31679.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105C54. Bacteria.
ENOG410XQKC. LUCA.
HOGENOMiHOG000077075.
InParanoidiP31679.
KOiK08368.
OMAiCLVIPSQ.
PhylomeDBiP31679.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P31679-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQPSRNFDDL KFSSIHRRIL LWGSGGPFLD GYVLVMIGVA LEQLTPALKL
60 70 80 90 100
DADWIGLLGA GTLAGLFVGT SLFGYISDKV GRRKMFLIDI IAIGVISVAT
110 120 130 140 150
MFVSSPVELL VMRVLIGIVI GADYPIATSM ITEFSSTRQR AFSISFIAAM
160 170 180 190 200
WYVGATCADL VGYWLYDVEG GWRWMLGSAA IPCLLILIGR FELPESPRWL
210 220 230 240 250
LRKGRVKECE EMMIKLFGEP VAFDEEQPQQ TRFRDLFNRR HFPFVLFVAA
260 270 280 290 300
IWTCQVIPMF AIYTFGPQIV GLLGLGVGKN AALGNVVISL FFMLGCIPPM
310 320 330 340 350
LWLNTAGRRP LLIGSFAMMT LALAVLGLIP DMGIWLVVMA FAVYAFFSGG
360 370 380 390 400
PGNLQWLYPN ELFPTDIRAS AVGVIMSLSR IGTIVSTWAL PIFINNYGIS
410 420 430 440
NTMLMGAGIS LFGLLISVAF APETRGMSLA QTSNMTIRGQ RMG
Length:443
Mass (Da):48,667
Last modified:November 1, 1997 - v2
Checksum:iAEF484D8B109DE05
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC73156.1.
AP009048 Genomic DNA. Translation: BAB96613.2.
PIRiE64725.
RefSeqiNP_414587.1. NC_000913.3.
WP_001183198.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73156; AAC73156; b0045.
BAB96613; BAB96613; BAB96613.
GeneIDi944766.
KEGGiecj:JW0044.
eco:b0045.
PATRICi32115189. VBIEscCol129921_0046.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC73156.1.
AP009048 Genomic DNA. Translation: BAB96613.2.
PIRiE64725.
RefSeqiNP_414587.1. NC_000913.3.
WP_001183198.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP31679.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262202. 172 interactors.
STRINGi511145.b0045.

Protein family/group databases

TCDBi2.A.1.1.114. the major facilitator superfamily (mfs).

Proteomic databases

PaxDbiP31679.
PRIDEiP31679.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73156; AAC73156; b0045.
BAB96613; BAB96613; BAB96613.
GeneIDi944766.
KEGGiecj:JW0044.
eco:b0045.
PATRICi32115189. VBIEscCol129921_0046.

Organism-specific databases

EchoBASEiEB1527.
EcoGeneiEG11566. yaaU.

Phylogenomic databases

eggNOGiENOG4105C54. Bacteria.
ENOG410XQKC. LUCA.
HOGENOMiHOG000077075.
InParanoidiP31679.
KOiK08368.
OMAiCLVIPSQ.
PhylomeDBiP31679.

Enzyme and pathway databases

BioCyciEcoCyc:YAAU-MONOMER.
ECOL316407:JW0044-MONOMER.

Miscellaneous databases

PROiP31679.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYAAU_ECOLI
AccessioniPrimary (citable) accession number: P31679
Secondary accession number(s): P31578, P75628
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: November 1, 1997
Last modified: November 30, 2016
This is version 134 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.