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P31679 (YAAU_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 100. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative metabolite transport protein yaaU
Gene names
Name:yaaU
Synonyms:yabE
Ordered Locus Names:b0045, JW0044
OrganismEscherichia coli (strain K12)
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length443 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Subcellular location

Cell inner membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]

Ontologies

Keywords
   Biological processTransport
   Cellular componentCell inner membrane
Cell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiontransmembrane transporter activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 443443Putative metabolite transport protein yaaU
PRO_0000050481

Regions

Topological domain1 – 1818Cytoplasmic Potential
Transmembrane19 – 3921Helical; Name=1; Potential
Topological domain40 – 5314Periplasmic Potential
Transmembrane54 – 7421Helical; Name=2; Potential
Topological domain75 – 8410Cytoplasmic Potential
Transmembrane85 – 10521Helical; Name=3; Potential
Topological domain106 – 1138Periplasmic Potential
Transmembrane114 – 13421Helical; Name=4; Potential
Topological domain135 – 14511Cytoplasmic Potential
Transmembrane146 – 16621Helical; Name=5; Potential
Topological domain167 – 1737Periplasmic Potential
Transmembrane174 – 19421Helical; Name=6; Potential
Topological domain195 – 24147Cytoplasmic Potential
Transmembrane242 – 26221Helical; Name=7; Potential
Topological domain263 – 28220Periplasmic Potential
Transmembrane283 – 30321Helical; Name=8; Potential
Topological domain304 – 3096Cytoplasmic Potential
Transmembrane310 – 32920Helical; Name=9; Potential
Topological domain330 – 3345Periplasmic Potential
Transmembrane335 – 35723Helical; Name=10; Potential
Topological domain358 – 37316Cytoplasmic Potential
Transmembrane374 – 39421Helical; Name=11; Potential
Topological domain395 – 4017Periplasmic Potential
Transmembrane402 – 42221Helical; Name=12; Potential
Topological domain423 – 44321Cytoplasmic Potential

Sequences

Sequence LengthMass (Da)Tools
P31679 [UniParc].

Last modified November 1, 1997. Version 2.
Checksum: AEF484D8B109DE05

FASTA44348,667
        10         20         30         40         50         60 
MQPSRNFDDL KFSSIHRRIL LWGSGGPFLD GYVLVMIGVA LEQLTPALKL DADWIGLLGA 

        70         80         90        100        110        120 
GTLAGLFVGT SLFGYISDKV GRRKMFLIDI IAIGVISVAT MFVSSPVELL VMRVLIGIVI 

       130        140        150        160        170        180 
GADYPIATSM ITEFSSTRQR AFSISFIAAM WYVGATCADL VGYWLYDVEG GWRWMLGSAA 

       190        200        210        220        230        240 
IPCLLILIGR FELPESPRWL LRKGRVKECE EMMIKLFGEP VAFDEEQPQQ TRFRDLFNRR 

       250        260        270        280        290        300 
HFPFVLFVAA IWTCQVIPMF AIYTFGPQIV GLLGLGVGKN AALGNVVISL FFMLGCIPPM 

       310        320        330        340        350        360 
LWLNTAGRRP LLIGSFAMMT LALAVLGLIP DMGIWLVVMA FAVYAFFSGG PGNLQWLYPN 

       370        380        390        400        410        420 
ELFPTDIRAS AVGVIMSLSR IGTIVSTWAL PIFINNYGIS NTMLMGAGIS LFGLLISVAF 

       430        440 
APETRGMSLA QTSNMTIRGQ RMG

« Hide

References

[1]"Systematic sequencing of the Escherichia coli genome: analysis of the 0-2.4 min region."
Yura T., Mori H., Nagai H., Nagata T., Ishihama A., Fujita N., Isono K., Mizobuchi K., Nakata A.
Nucleic Acids Res. 20:3305-3308(1992) [PubMed: 1630901] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12.
[2]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[3]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], SEQUENCE REVISION.
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		U00096 Genomic DNA. Translation: AAC73156.1.
AP009048 Genomic DNA. Translation: BAB96613.2.
PIRE64725.
RefSeqNP_414587.1. NC_000913.2.

3D structure databases

ProteinModelPortalP31679.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBESCT00000002066; EBESCP00000002066; EBESCG00000001686.
EBESCT00000016502; EBESCP00000015793; EBESCG00000015562.
GeneID944766.
GenomeReviewsGene locus JW0044 in contig AP009048_GR.
Gene locus b0045 in contig U00096_GR.
KEGGecj:JW0044.
eco:b0045.
PATRIC32115189. VBIEscCol129921_0046.

Organism-specific databases

EchoBASEEB1527.
EcoGeneEG11566. yaaU.

Phylogenomic databases

eggNOGCOG0477.
GeneTreeEBGT00050000008817.
HOGENOMHBG516586.
OMAELDAQWI.
PhylomeDBP31679.
ProtClustDBCLSK879551.

Enzyme and pathway databases

BioCycEcoCyc:YAAU-MONOMER.

Gene expression databases

GenevestigatorP31679.

Family and domain databases

InterProIPR020846. MFS_dom.
IPR016196. MFS_dom_general_subst_transpt.
IPR005828. Sub_transporter.
[Graphical view]
KOK08368.
PfamPF00083. Sugar_tr. 1 hit.
[Graphical view]
SUPFAMSSF103473. MFS_gen_substrate_transporter. 1 hit.
PROSITEPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. False negative.
PS00217. SUGAR_TRANSPORT_2. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameYAAU_ECOLI
AccessionPrimary (citable) accession number: P31679
Secondary accession number(s): P31578, P75628
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: November 1, 1997
Last modified: January 25, 2012
This is version 100 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents