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Protein

Bacteriophage adsorption protein A

Gene

nfrA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

(Microbial infection) Allows N4 phage attachment by binding to the viral non-contractile sheath protein.1 Publication

Enzyme and pathway databases

BioCyciEcoCyc:EG11740-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Bacteriophage adsorption protein ACurated
Alternative name(s):
Bacteriophage N4 adsorption protein A
Gene namesi
Name:nfrA
Ordered Locus Names:b0568, JW0557
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11740 nfrA

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_000002180928 – 990Bacteriophage adsorption protein AAdd BLAST963

Proteomic databases

PaxDbiP31600
PRIDEiP31600

Interactioni

Subunit structurei

(Microbial infection) Interacts with N4 phage non-contractile sheath protein; this interaction is essential for viral adsorption to the host.1 Publication

Protein-protein interaction databases

BioGridi4259890, 194 interactors
DIPiDIP-10332N
IntActiP31600, 11 interactors
STRINGi316385.ECDH10B_0634

Structurei

3D structure databases

ProteinModelPortaliP31600
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati81 – 114TPR 1Add BLAST34
Repeati612 – 645TPR 2Add BLAST34
Repeati646 – 679TPR 3Add BLAST34

Keywords - Domaini

Repeat, Signal, TPR repeat

Phylogenomic databases

eggNOGiENOG41090FC Bacteria
COG0457 LUCA
HOGENOMiHOG000117813
KOiK11739
OMAiWDHALGE

Family and domain databases

Gene3Di1.25.40.10, 2 hits
InterProiView protein in InterPro
IPR025137 NfrA_C
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
PfamiView protein in Pfam
PF13283 NfrA_C, 1 hit
SMARTiView protein in SMART
SM00028 TPR, 2 hits
SUPFAMiSSF48452 SSF48452, 4 hits
PROSITEiView protein in PROSITE
PS50005 TPR, 3 hits
PS50293 TPR_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P31600-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKENNLNRVI GWSGLLLTSL LSTSALADNI GTSAEELGLS DYRHFVIYPR
60 70 80 90 100
LDKALKAQKN NDEATAIREF EYIHQQVPDN IPLTLYLAEA YRHFGHDDRA
110 120 130 140 150
RLLLEDQLKR HPGDARLERS LAAIPVEVKS VTTVEELLAQ QKACDAAPTL
160 170 180 190 200
RCRSEVGQNA LRLAQLPVAR AQLNDATFAA SPEGKTLRTD LLQRAIYLKQ
210 220 230 240 250
WSQADTLYNE ARQQNTLSAA ERRQWFDVLL AGQLDDRILA LQSQGIFTDP
260 270 280 290 300
QSYITYATAL AYRGEKARLQ HYLIENKPLF TTDAQEKSWL YLLSKYSANP
310 320 330 340 350
VQALANYTVQ FADNRQYVVG ATLPVLLKEG QYDAAQKLLA TLPANEMLEE
360 370 380 390 400
RYAVSVATRN KAEALRLARL LYQQEPANLT RLDQLTWQLM QNEQSREAAD
410 420 430 440 450
LLLQRYPFQG DARVSQTLMA RLASLLESHP YLATPAKVAI LSKPLPLAEQ
460 470 480 490 500
RQWQSQLPGI ADNCPAIVRL LGDMSPSYDA AAWNRLAKCY RDTLPGVALY
510 520 530 540 550
AWLQAEQRQP SAWQHRAVAY QAYQVEDYAT ALAAWQKISL HDMSNEDLLA
560 570 580 590 600
AANTAQAAGN GAARDRWLQQ AEKRGLGSNA LYWWLHAQRY IPGQPELALN
610 620 630 640 650
DLTRSINIAP SANAYVARAT IYRQRHNVPA AVSDLRAALE LEPNNSNTQA
660 670 680 690 700
ALGYALWDSG DIAQSREMLE PAHKGLPDDP ALIRQLAYVN QRLDDMPATQ
710 720 730 740 750
HYARLVIDDI DNQALITPLT PEQNQQRFNF RRLHEEVGRR WTFSFDSSIG
760 770 780 790 800
LRSGAMSTAN NNVGGAAPGK SYRSYGQLEA EYRIGRNMLL EGDLLSVYSR
810 820 830 840 850
VFADTGENGV MMPVKNPMSG TGLRWKPLRD QIFFIAVEQQ LPLNGQNGAS
860 870 880 890 900
DTMLRASASF FNGGKYSDEW HPNGSGWFAQ NLYLDAAQYI RQDIQAWTAD
910 920 930 940 950
YRVSWHQKVA NGQTIEPYAH VQDNGYRDKG TQGAQLGGVG VRWNIWTGET
960 970 980 990
HYDAWPHKVS LGVEYQHTFK AINQRNGERN NAFLTIGVHW
Length:990
Mass (Da):111,308
Last modified:July 1, 1993 - v1
Checksum:iAAA616665D1C2E72
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L16945 Unassigned DNA Translation: AAC36849.1
U82598 Genomic DNA Translation: AAB40766.1
U00096 Genomic DNA Translation: AAC73669.1
AP009048 Genomic DNA Translation: BAA35202.1
PIRiB49351
RefSeqiNP_415100.1, NC_000913.3
WP_000662357.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73669; AAC73669; b0568
BAA35202; BAA35202; BAA35202
GeneIDi944741
KEGGiecj:JW0557
eco:b0568
PATRICifig|1411691.4.peg.1706

Similar proteinsi

Entry informationi

Entry nameiNFRA_ECOLI
AccessioniPrimary (citable) accession number: P31600
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: July 1, 1993
Last modified: March 28, 2018
This is version 136 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

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