P31531 (1A1C_SOYBN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
1-aminocyclopropane-1-carboxylate synthase
Short name=ACC synthase
EC=4.4.1.14

Alternative name(s):
S-adenosyl-L-methionine methylthioadenosine-lyase

Gene names

Name:

ACS1

Organism

Glycine max (Soybean) (Glycine hispida)

Taxonomic identifier

3847 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › fabids › Fabales › Fabaceae › Papilionoideae › Phaseoleae › Glycine

Protein attributes

Sequence length	484 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Catalyzes the formation of 1-aminocyclopropane-1-carboxylate, a direct precursor of ethylene in higher plants.
Catalytic activity	S-adenosyl-L-methionine = 1-aminocyclopropane-1-carboxylate + methylthioadenosine.
Cofactor	Pyridoxal phosphate.
Pathway	Alkene biosynthesis; ethylene biosynthesis via S-adenosyl-L-methionine; ethylene from S-adenosyl-L-methionine: step 1/2.
Subunit structure	Homodimer.
Sequence similarities	Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

Ontologies

Keywords
Biological process	Ethylene biosynthesis Fruit ripening
Ligand	Pyridoxal phosphate S-adenosyl-L-methionine
Molecular function	Lyase
Gene Ontology (GO)
Biological process	ethylene biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW ripening Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	1-aminocyclopropane-1-carboxylate synthase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro transferase activity, transferring nitrogenous groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 484	484	1-aminocyclopropane-1-carboxylate synthase		PRO_0000123919
Amino acid modifications
	Modified residue	279	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	P31531 [UniParc]. Last modified July 1, 1993. Version 1. Checksum: 152F7AD12B992987	FASTA	484	54,731
	10 20 30 40 50 60 MGLMDVDQTQ LLSKMVIGDG HGEASPYFDG WKAYDENPFH PKENPNGVIQ MGLAENQLTS 70 80 90 100 110 120 DLVEDWILNN PEASICTPEG INDFRAIANF QDYHGLPEFR NAVAKFMGRT RGNRVTFDPD 130 140 150 160 170 180 RIVMSGGATG AHEVTTFCLA DPGDAFLVPI PYYPGFDRDL RWRTGIKLVP VMCDSSNNFK 190 200 210 220 230 240 LTKQALEDAY EKAKEDNIRV KGLLITNPSN PLGTVMDRNT LRTVMSFINE KRIHLVSDEI 250 260 270 280 290 300 YSATVFSHPS FISIAEILEE DTDIECDRNL VHIVYSLSKD MGFPGFRVGI IYSYNDAVVH 310 320 330 340 350 360 CARKMSSFGL VSTQTQYLLA SMLNDDEFVE SFLVESAKRL AQRHRVFTGG LAKVGIKCLQ 370 380 390 400 410 420 SNAGLFVWMD LRQLLKKPTL DSEMELWRVI IDEVKINVSP GSSFHCTEPG WFRVCYANMD 430 440 450 460 470 480 DMAVQIALQR IRNFVLQNKE IMVPNKKHCW HSNLRLSLKT RRFDDIMMSP HSPIPQSPLV KATI

References

[1]	Liu D., Li N., Mattoo A.K. Submitted (JUN-1992) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Century. Tissue: Leaf.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X67100 mRNA. Translation: CAA47474.1.
PIR	S25002.
RefSeq	NP_001236858.1. NM_001249929.1.
UniGene	Gma.33875.
3D structure databases
ProteinModelPortal	P31531.
SMR	P31531. Positions 11-435.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	Gmax_FGT32853; Gmax_FGP32853; Gmax_FG32853.
GeneID	547976.
Gene expression databases
Genevestigator	P31531.
Family and domain databases
InterPro	IPR001176. ACC_synthase. IPR004839. Aminotransferase_I/II. IPR004838. NHTrfase_class1_PyrdxlP-BS. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 2 hits.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
PRINTS	PR00753. ACCSYNTHASE.
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
PROSITE	PS00105. AA_TRANSFER_CLASS_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

1A1C_SOYBN

Accession

Primary (citable) accession number: P31531

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 1993
Last sequence update:	July 1, 1993
Last modified:	December 14, 2011
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program