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P31522 (PSAA_YERPE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
pH 6 antigen
Alternative name(s):
Adhesin
Antigen 4
Gene names
Name:psaA
Ordered Locus Names:YPO1303, y2882, YP_1289
OrganismYersinia pestis [Reference proteome] [HAMAP]
Taxonomic identifier632 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia

Protein attributes

Sequence length158 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Fibrillar structure, part of fimbriae, necessary for full virulence.

Subunit structure

Forms a homopolymer composed of subunits assembled in a large structure.

Subcellular location

Fimbrium.

Induction

Expressed inside macrophages under acidic pH and at 37 degrees Celsius.

Sequence caution

The sequence AAM86433.1 differs from that shown. Reason: Erroneous initiation.

The sequence AAS61532.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processVirulence
   Cellular componentFimbrium
   DomainSignal
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processpathogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentpilus

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2626
Chain27 – 158132pH 6 antigen
PRO_0000009240

Secondary structure

........................... 158
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P31522 [UniParc].

Last modified July 1, 1993. Version 1.
Checksum: E475AEE11C5DC2FC

FASTA15817,233
        10         20         30         40         50         60 
MKMKCFAKNA LAVTTLMIAA CGMANASTVI NSKDVSGEVT VKQGNTFHVD FAPNTGEIFA 

        70         80         90        100        110        120 
GKQPGDVTMF TLTMGDTAPH GGWRLIPTGD SKGGYMISAD GDYVGLYSYM MSWVGIDNNW 

       130        140        150 
YINDDSPKDI KDHLYVKAGT VLKPTTYKFT GRVEEYVF 

« Hide

References

« Hide 'large scale' references
[1]"Yersinia pestis pH 6 antigen forms fimbriae and is induced by intracellular association with macrophages."
Lindler L.E., Tall B.D.
Mol. Microbiol. 8:311-324(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: KIM5 / Biovar Mediaevalis.
[2]Cherepavov P.A.
Submitted (MAY-1996) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: EV 76.
[3]"Genome sequence of Yersinia pestis, the causative agent of plague."
Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G., Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L., Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M., Chillingworth T., Cronin A., Davies R.M. expand/collapse author list , Davis P., Dougan G., Feltwell T., Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S., Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S., Barrell B.G.
Nature 413:523-527(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CO-92 / Biovar Orientalis.
[4]"Genome sequence of Yersinia pestis KIM."
Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P., Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D., Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A., Nilles M.L. expand/collapse author list , Matson J.S., Blattner F.R., Perry R.D.
J. Bacteriol. 184:4601-4611(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: KIM10+ / Biovar Mediaevalis.
[5]"Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R. expand/collapse author list , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 91001 / Biovar Mediaevalis.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M86713 Genomic DNA. Translation: AAA27662.1.
X97759 Genomic DNA. Translation: CAA66355.1.
AL590842 Genomic DNA. Translation: CAL19956.1.
AE009952 Genomic DNA. Translation: AAM86433.1. Different initiation.
AE017042 Genomic DNA. Translation: AAS61532.1. Different initiation.
PIRAB0159.
S32926.
RefSeqNP_670182.1. NC_004088.1.
NP_992655.1. NC_005810.1.
YP_002346328.1. NC_003143.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4F8LX-ray1.50A27-158[»]
4F8NX-ray2.50A27-158[»]
4F8OX-ray1.90A27-158[»]
4F8PX-ray2.05A/B27-158[»]
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING214092.YPO1303.

Protocols and materials databases

DNASU1147829.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM86433; AAM86433; y2882.
AAS61532; AAS61532; YP_1289.
GeneID1147829.
1174145.
2766170.
KEGGype:YPO1303.
ypk:y2882.
ypm:YP_1289.

Phylogenomic databases

eggNOGNOG72060.
HOGENOMHOG000219282.
OMATIKQGNT.
OrthoDBEOG6GR38Z.

Enzyme and pathway databases

BioCycYPES214092:GKDD-1292-MONOMER.

Family and domain databases

PROSITEPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePSAA_YERPE
AccessionPrimary (citable) accession number: P31522
Secondary accession number(s): Q0WHB0
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: July 1, 1993
Last modified: May 14, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references