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Protein

Uncharacterized HTH-type transcriptional regulator YieP

Gene

yieP

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi40 – 59H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:EG11733-MONOMER.
ECOL316407:JW5608-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized HTH-type transcriptional regulator YieP
Gene namesi
Name:yieP
Ordered Locus Names:b3755, JW5608
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11733. yieP.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000506821 – 230Uncharacterized HTH-type transcriptional regulator YiePAdd BLAST230

Proteomic databases

PaxDbiP31475.
PRIDEiP31475.

Interactioni

Protein-protein interaction databases

BioGridi4262602. 21 interactors.
STRINGi511145.b3755.

Structurei

3D structure databases

ProteinModelPortaliP31475.
SMRiP31475.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 80HTH gntR-typePROSITE-ProRule annotationAdd BLAST69

Sequence similaritiesi

Contains 1 HTH gntR-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4107EJG. Bacteria.
COG2186. LUCA.
HOGENOMiHOG000273996.
OMAiMTRENFD.
PhylomeDBiP31475.

Family and domain databases

CDDicd07377. WHTH_GntR. 1 hit.
Gene3Di1.10.10.10. 1 hit.
1.20.120.530. 1 hit.
InterProiIPR011711. GntR_C.
IPR008920. TF_FadR/GntR_C.
IPR000524. Tscrpt_reg_HTH_GntR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF07729. FCD. 1 hit.
PF00392. GntR. 1 hit.
[Graphical view]
PRINTSiPR00035. HTHGNTR.
SMARTiSM00895. FCD. 1 hit.
SM00345. HTH_GNTR. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF48008. SSF48008. 1 hit.
PROSITEiPS50949. HTH_GNTR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P31475-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLSAQQLAA QKNLSYVLAE KLAQRILKGE YEPGTILPGE IELGEQFGVS
60 70 80 90 100
RTAVREAVKT LTAKGMVLPR PRIGTRVMPQ SNWNFLDQEL LTWWMTEENF
110 120 130 140 150
HQVIDHFLVM RICLEPQACL LAATVGTAEQ KAHLNTLMAE MAALKENFRR
160 170 180 190 200
ERWIEVDMAW HEHIYEMSAN PFLTSFASLF HSVYHTYFTS ITSDTVIKLD
210 220 230
LHQAIVDAII QSDGDAAFKA CQALLRSPDK
Length:230
Mass (Da):26,076
Last modified:October 11, 2004 - v3
Checksum:i671FE97B115C6FD4
GO

Sequence cautioni

The sequence AAA62108 differs from that shown. Reason: Frameshift at position 21.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti123Missing in AAA62108 (PubMed:7686882).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L10328 Genomic DNA. Translation: AAA62108.1. Frameshift.
U00096 Genomic DNA. Translation: AAT48205.1.
AP009048 Genomic DNA. Translation: BAE77533.1.
RefSeqiWP_001131164.1. NZ_LN832404.1.
YP_026245.1. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAT48205; AAT48205; b3755.
BAE77533; BAE77533; BAE77533.
GeneIDi948263.
KEGGiecj:JW5608.
eco:b3755.
PATRICi32123009. VBIEscCol129921_3880.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L10328 Genomic DNA. Translation: AAA62108.1. Frameshift.
U00096 Genomic DNA. Translation: AAT48205.1.
AP009048 Genomic DNA. Translation: BAE77533.1.
RefSeqiWP_001131164.1. NZ_LN832404.1.
YP_026245.1. NC_000913.3.

3D structure databases

ProteinModelPortaliP31475.
SMRiP31475.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262602. 21 interactors.
STRINGi511145.b3755.

Proteomic databases

PaxDbiP31475.
PRIDEiP31475.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAT48205; AAT48205; b3755.
BAE77533; BAE77533; BAE77533.
GeneIDi948263.
KEGGiecj:JW5608.
eco:b3755.
PATRICi32123009. VBIEscCol129921_3880.

Organism-specific databases

EchoBASEiEB1684.
EcoGeneiEG11733. yieP.

Phylogenomic databases

eggNOGiENOG4107EJG. Bacteria.
COG2186. LUCA.
HOGENOMiHOG000273996.
OMAiMTRENFD.
PhylomeDBiP31475.

Enzyme and pathway databases

BioCyciEcoCyc:EG11733-MONOMER.
ECOL316407:JW5608-MONOMER.

Miscellaneous databases

PROiP31475.

Family and domain databases

CDDicd07377. WHTH_GntR. 1 hit.
Gene3Di1.10.10.10. 1 hit.
1.20.120.530. 1 hit.
InterProiIPR011711. GntR_C.
IPR008920. TF_FadR/GntR_C.
IPR000524. Tscrpt_reg_HTH_GntR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF07729. FCD. 1 hit.
PF00392. GntR. 1 hit.
[Graphical view]
PRINTSiPR00035. HTHGNTR.
SMARTiSM00895. FCD. 1 hit.
SM00345. HTH_GNTR. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF48008. SSF48008. 1 hit.
PROSITEiPS50949. HTH_GNTR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYIEP_ECOLI
AccessioniPrimary (citable) accession number: P31475
Secondary accession number(s): Q2M873, Q6BF09
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: October 11, 2004
Last modified: November 2, 2016
This is version 121 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.