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Protein

Uncharacterized protein YieK

Gene

yieK

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei66 – 661Proton acceptorBy similarity
Active sitei129 – 1291By similarity
Active sitei131 – 1311Proton acceptorBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:EG11728-MONOMER.
ECOL316407:JW5613-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein YieK
Gene namesi
Name:yieK
Ordered Locus Names:b3718, JW5613
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11728. yieK.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 240240Uncharacterized protein YieKPRO_0000160191Add
BLAST

Proteomic databases

PaxDbiP31470.

Interactioni

Protein-protein interaction databases

BioGridi4263200. 3 interactions.
STRINGi511145.b3718.

Structurei

3D structure databases

ProteinModelPortaliP31470.
SMRiP31470. Positions 1-240.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4107VKM. Bacteria.
COG0363. LUCA.
HOGENOMiHOG000064978.
InParanoidiP31470.
OMAiNNQVFDQ.
OrthoDBiEOG615VH1.
PhylomeDBiP31470.

Family and domain databases

InterProiIPR006148. Glc/Gal-6P_isomerase.
IPR004547. Glucosamine6P_isomerase.
IPR018321. Glucosamine6P_isomerase_CS.
[Graphical view]
PANTHERiPTHR11280. PTHR11280. 1 hit.
PfamiPF01182. Glucosamine_iso. 1 hit.
[Graphical view]
PROSITEiPS01161. GLC_GALNAC_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P31470-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLIITEDYQ EMSRVAAHHL LGYMSKTRRV NLAITAGSTP KGMYEYLTTL
60 70 80 90 100
VKGKPWYDNC YFYNFDEIPF RGKEGEGVTI TNLRNLFFTP AGIKEENIQK
110 120 130 140 150
LTIDNYREHD QKLAREGGLD LVVLGLGADG HFCGNLPNTT HFHEQTVEFP
160 170 180 190 200
IQGEMVDIVA HGELGGDFSL VPDSYVTMGP KSIMAAKNLL IIVSGAGKAQ
210 220 230 240
ALKNVLQGPV TEDVPASVLQ LHPSLMVIAD KAAAAELALG
Length:240
Mass (Da):26,279
Last modified:October 11, 2004 - v3
Checksum:iEAFCCFC194DE4481
GO

Sequence cautioni

The sequence AAA62069.1 differs from that shown. Reason: Frameshift at position 17. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti233 – 2408AAAELALG → VPQN in AAA62069 (PubMed:7686882).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L10328 Genomic DNA. Translation: AAA62069.1. Frameshift.
U00096 Genomic DNA. Translation: AAT48202.1.
AP009048 Genomic DNA. Translation: BAE77570.1.
RefSeqiWP_000766900.1. NZ_LN832404.1.
YP_026242.1. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAT48202; AAT48202; b3718.
BAE77570; BAE77570; BAE77570.
GeneIDi948229.
KEGGiecj:JW5613.
eco:b3718.
PATRICi32122931. VBIEscCol129921_3841.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L10328 Genomic DNA. Translation: AAA62069.1. Frameshift.
U00096 Genomic DNA. Translation: AAT48202.1.
AP009048 Genomic DNA. Translation: BAE77570.1.
RefSeqiWP_000766900.1. NZ_LN832404.1.
YP_026242.1. NC_000913.3.

3D structure databases

ProteinModelPortaliP31470.
SMRiP31470. Positions 1-240.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263200. 3 interactions.
STRINGi511145.b3718.

Proteomic databases

PaxDbiP31470.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAT48202; AAT48202; b3718.
BAE77570; BAE77570; BAE77570.
GeneIDi948229.
KEGGiecj:JW5613.
eco:b3718.
PATRICi32122931. VBIEscCol129921_3841.

Organism-specific databases

EchoBASEiEB1679.
EcoGeneiEG11728. yieK.

Phylogenomic databases

eggNOGiENOG4107VKM. Bacteria.
COG0363. LUCA.
HOGENOMiHOG000064978.
InParanoidiP31470.
OMAiNNQVFDQ.
OrthoDBiEOG615VH1.
PhylomeDBiP31470.

Enzyme and pathway databases

BioCyciEcoCyc:EG11728-MONOMER.
ECOL316407:JW5613-MONOMER.

Miscellaneous databases

PROiP31470.

Family and domain databases

InterProiIPR006148. Glc/Gal-6P_isomerase.
IPR004547. Glucosamine6P_isomerase.
IPR018321. Glucosamine6P_isomerase_CS.
[Graphical view]
PANTHERiPTHR11280. PTHR11280. 1 hit.
PfamiPF01182. Glucosamine_iso. 1 hit.
[Graphical view]
PROSITEiPS01161. GLC_GALNAC_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "DNA sequence and analysis of 136 kilobases of the Escherichia coli genome: organizational symmetry around the origin of replication."
    Burland V.D., Plunkett G. III, Daniels D.L., Blattner F.R.
    Genomics 16:551-561(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], SEQUENCE REVISION TO N-TERMINUS.
    Strain: K12 / MG1655 / ATCC 47076.
  3. Cited for: SEQUENCE REVISION.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiYIEK_ECOLI
AccessioniPrimary (citable) accession number: P31470
Secondary accession number(s): Q2M836, Q6BF12
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: October 11, 2004
Last modified: January 20, 2016
This is version 101 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.